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pelvic pain
R-GU II
69
Medical
Graduate
10/27/2010

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Term
what characterizes acute pelvic pain?
Definition
acute pelvic pain usually has usually sudden onset, is mostly localized, has an associated event, lasts 2-3 months, can be treated conservatively, and is reproducible.
Term
what characterizes chronic pelvic pain?
Definition
chronic pelvic pain usually lasts 6+ months (duration may be arbitrary), lacks empirical validation, behavioral/emotional/biomechanical changes occur, and a combination of medical/sx/psychological care may be necessary.
Term
what is sub acute pelvic pain?
Definition
not acute or chronic, lasts between 2-6 months, mostly localized and intermittent and can be reproducible (even if etiology is unknown).
Term
what structures are often involved w/female pelvic pain?
Definition
uterus, fallopian tube, ovary and surrounding peritoneum
Term
what are pelvic pain "imitators"?
Definition
GI disorders, musculoskeletal abnormalities, CNS/PNS disease, vulvar vestibulitis/vulvodynia, and ureteral/bladder/urethral syndromes.
Term
what GI disorders can cause pelvic pain?
Definition
IBS, lactose intolerance, small bowel bacterial overgrowth, IBD, diverticular disease, levator ani syndrome, and endometriosis affecting the bowel
Term
what is the connection between IBS and dysmenorrhea?
Definition
61% of women w/dysmenorrhea have had some kind of functional bowel disorder (FBD), while only 20% w/dysmenorrhea had FBD. women w/IBS report increased symptoms w/menses. 50% of pts referred to gyn docs for pelvic pain have IBS (not good).
Term
does IBD have a relationship with menses?
Definition
no
Term
can endometriosis affect the bowel?
Definition
yes - pts w/endometriosis report painful bowel movement and in severe cases, endometriosis can cause bowel obstruction
Term
what musculoskeletal abnormalities can be associated with pelvic pain?
Definition
pelvic floor abnormalities, thoracolumbar syndrome, iliopectineal bursitis, fibromyalgia, myofascial pain syndromes, degenerative joint disease of the hip, pubic separations/strains, sacroiliac sprains/strains/displacements, diastasis recti (midline raphe of muscle is separated), and coccydynia
Term
what is the typical pelvic pain posture?
Definition
anteriorly tilted pelvis, increased lumbar lordosis, hyperextended knees, and center of gravity displaced anteriorly
Term
what is the function of the pelvic floor?
Definition
the pelvic floor supports the pelvic viscera by counteracting gravitational and intraabdominal forces
Term
what are symptoms of pelvic floor dysfunction (PFD)? what are they due to?
Definition
decreased strength, hypo/hypertonicity, and the levator ani (iliococcygeus/pubococcygeus) may also be involved. disuse and denervation appear to be the major factors in development of PFD - sedentary western lifestyles promoted prolonged sitting which stretches pelvic floor muscles (leads to hypotonicity), while squatting does not.
Term
what is the path of the pudendal nerve?
Definition
the pudendal nerve comes off S2,3,4 and goes through alcock's canal, and then innervates the pelvic floor muscles/sphincters.
Term
what peripheral nerves can get entrapped in the pelvis?
Definition
ilioinguinal, iliohypogastric, genitofemoral, lateral femoral cutaneous, epigastric
Term
what is the most common cause of peripheral neuropathy?
Definition
DM
Term
what are trigger points?
Definition
areas of nerve irritability where they penetrate muscle or are stuck in fascia which can mimic visceral pain disorders such as: heartburn, appendicitis, PID, ovarian cysts, dyspareunia, cholecystitis, bladder abnormalities, hernia, and peptic ulcer.
Term
what is fibromyalgia?
Definition
a form of non-articular rheumatism which shares characteristics w/myofascial pain syndrome and pts will often complain of coccygeal/pelvic pain, constipation, and diarrhea. global anxiety is also common to develop in these pts.
Term
what urinary tract abnormalities can cause pelvic pain?
Definition
post coital UTIs, urethritis (acute/chronic), urethral syndrome, urethral diverticulum, and interstitial cystitis
Term
what are the irritative voiding syndromes?
Definition
dysuria, frequency, suprapubic pain, and urgency
Term
what is interstitial cystitis?
Definition
a disease process usually found after numerous sx, workups w/CTs, etc that is characterized by *urgency/frequency/pelvic pain*. it is a dx of exclusion and diagnosed with a positive potassium sensitivity test and cystoscopy (petechiae may be seen along the bladder mucosa). this more often affects women.
Term
what are symptoms of urethral syndrome?
Definition
dysuria, frequency, urgency, suprapubic discomfort, voiding discomfort, and stranguria (painful, slow urination due to bladder/urethral spasms). often times there is no underlying pathology.
Term
who does urethral syndrome occur in?
Definition
women who have hypoestrogenism. also spasms from inflammatory problems/HSV.
Term
what are skene's duct?
Definition
ducts located at 4 & 8 o'clock outside the urethra which can get obstructed.
Term
what are the vulvar pain syndromes?
Definition
cyclic vulvovaginal candidiasis, vulvar vestibulitis, and essential vulvodynia.
Term
what is cyclic vulvovaginal candidiasis?
Definition
this is recurrent (most women respond to typical tx) and can result in pelvic pain/discomfort
Term
what is vulvar vestibulitis?
Definition
hyperesthesia of the vulva (limited to the vestibule - edge marked by hart's line), which occurs mostly in *younger women and erythema typically co-presents. these pts have pain w/sex, inserting a tampon, wearing tight jeans, riding horses, and riding a bicycle
Term
what is essential vulvodynia?
Definition
this is usually seen in *more mature women (perimenopausal), and its hallmarks include diffuse burning/itching/stinging. it is chronic and may be exacerbated by some kind of trauma (only a symptom - not a disease). dyspareunia is not a major problem. vulvar dermatoses (lichen sclerosis/planus and simplex chonicus) may initiated these symptoms, but once treated the vulvodynia may persist.
Term
what is dysesthetic vulvodynia?
Definition
end stage for no cause determined pudendal neuralgia
Term
what is IBS treated with?
Definition
medical management is directed toward the most predominant symptom (diarrhea or constipation). tricyclic antidepressants can help with spasms, *probiotics, psychological and OMT can also help.
Term
what is IBD treated with?
Definition
sulfas, steroids, sometimes segmental resection
Term
how is diverticular disease treated?
Definition
antibx and diet change
Term
how can pelvic floor dysfunction be treated?
Definition
education (muscular relaxation/contraction), biofeedback (EMG/skin electrodes), manual soft tissue massage (OMT, friction, thiels massage), trigger point injections (lidocaine, cortisone), magic spray'n'stretch, functional electrical stimulation (helps pts determine what muscles they need to work on relaxing/contracting), US, heat/ice, medication, and tricyclic antidepressants (improve sleep disturbances)
Term
what is one effective way of preventing pelvic pain?
Definition
c-section
Term
how are myofascial pain syndromes treated?
Definition
same as pelvic floor dysfunction (cortisone, marcaine, vapocoolant, OMT, functional electrical stimulation, and US)
Term
how is urethral syndrome treated?
Definition
if antibx don't work - can try urethral calibration/dilation, topical estrogen (in menopausal women), DMSO, anti-inflammatories, and muscle relaxants.
Term
can interstitial cystitis be cured?
Definition
no, therapy is only palliative and includes: amitriptyline, gabapentin, intravesical cocktails, electrical stimulation/nerve blocks, botox, and interstim (wires implanted in S2/S3 foramina which pt can activate to relax the bladder)
Term
what is one tx for vulvar vestibulitis?
Definition
vestibulectomy (includes hymenal ring out to labia)
Term
what is endometriosis?
Definition
a painful chronic disease where endometrial tissue (glands+stroma) grow outside the endometrium and proliferate during the secretory phase of the menstrual cycle. it is a benign but progressive disorder and usually starts in the 3rd-4th decade of life. remission is the goal of tx.
Term
what structures does endometriosis involve? what can happen to them?
Definition
the ovaries, fallopian tubes, ureters, peritoneum surrounding the pelvis, bladder, and bowel. more rarely: the lungs, C-section scars, appendix/appendectomy scars, episiotomy, cervix and vaginal cuff (in hysterectomy pts). any of these structures can develop peritoneal implants, fibrosis, adhesions, and formation of endometriomas
Term
what do women w/endometriosis report more of?
Definition
emotional distress, dysmenorrhea, infertility, emotional distress, depression, and dyspareunia
Term
what is the pathogenesis of endometriosis?
Definition
endometrial tissue implants on extra-endometrial tissue. when the menstrual cycle goes from proliferative to the luteal phase, these glands swell and increase blood supply = bleeding and eventually fibrosis/endometrioma formation (enveloped glandular tissue).
Term
where is the most common place for endometriosis to develop?
Definition
the ovaries
Term
what are the theories for endometriosis pathogenesis?
Definition
retrograde menstruation (menses efflux out of fallopian tubes -> peritoneum), metaplasia, embryonic rests of mullerian tissue (genetic), vascular/lymphatic transport, and immune dysfunction
Term
what factors may increase propensity for endometriosis?
Definition
cell invasiveness, immune system dysfunction, endocrine dysfunction, and higher numbers of endometrial cells reaching the peritoneal cavity.
Term
what signs/symptoms are associated with endometriosis?
Definition
dysmenorrhea (muscles and hormones are not in sync), dyspareunia (due to scarring on uterosacral ligaments), and infertility (scarring in fallopian tubes). pain and discomfort is determined by the areas of involvement.
Term
when are symptoms the most severe w/endometriosis?
Definition
endometriosis symptoms tend to be most severe a week prior to and during the menstrual cycle (improve after secretory phase and when menstruation occurs). some start at ovulation. severity of symptoms does not always correlate w/the extent of disease.
Term
what should be focused on in dx/tx of endometriosis?
Definition
need to discern/delineate goals, such as immediate fertility. focus attention on menstrual cycle, intercourse, and other activities which increase/affect pain.
Term
are staging and pain due to endometriosis related?
Definition
no - there is an inverse relationship between staging and pain.
Term
what does pain due to endometriosis depend on?
Definition
location, depth of invasion, inflammation, and whether there is stretching/scarring of tissue
Term
what are the types of endometriosis?
Definition
active (clear or red) and inactive (dark/gunpowder)
Term
what is medical management of endometriosis?
Definition
NSAIDs, OCPs (suppress ovulation), progestins (depo provera), and GnRH agonists
Term
what is surgical management of endometriosis?
Definition
consider preop US to ID endometriosis, operate in proliferative phase/suppress ovaries, administer bowel prep (may require bowel resection), acquire consent for possible laparotomy (if adhesions), ID all anatomy (check ureters, bowel, vessels, *diaphragm, *appendix, bladder, *cul-de-sac, *uterosacral ligaments), have a plan on method of tissue removal (cauterize/excise/ablate), and attempt adhesion prevention
Term
what is it called if diffuse pelvic endometriosis causes ovarian engorgement w/blood?
Definition
chocolate cyst
Term
how are superficial endometriotic lesions treated w/ablation? deep lesions?
Definition
superficial: destroy w/laser/elctrosx/thermal energy. deep: outline w/laser, pull up and undercut w/laser.
Term
what are likely areas of complications w/endometriosis?
Definition
bowel, ureters, vascular (superficial/deep epigastrics, iliac and great vessels), and bladder. (have a back up plan, b/c mistakes are going to occur)
Term
what is laparoscopic uterine suspension?
Definition
if the uterus is folded backwards into the cul-de-sac (retroverted uterus), endometriosis is more likely to cause pain, so this procedure lifts the uterus to prevent endometriosis/pain in that area by shortening the round ligaments via plication.
Term
what characterizes results with diagnostic sx for endometriosis?
Definition
a certain number of people have improvement, but pain quickly returns
Term
what characterizes results with resection/ablation for endometriosis?
Definition
about 50% are still improved 1 yr later
Term
what stage of endometriosis responds best to sx?
Definition
stage III (harder to see lesions in earlier stages)
Term
what are reasons for pain recurrence after sx for endometriosis?
Definition
depth of residual disease and microscopic/atypical lesions
Term
what *postop methods can enhance outcome of endometriosis sx?
Definition
OCPs/progestins, danazol (synthetic testosterone), and lupron - a GnRH agonist (MOA: negative feedback). sx only partial tx, so postop tx is recommended unless these pts want to get pregnant immediately.
Term
why does postop endometriosis tx involve lupron (leuprolide) more and more? how long is this tx?
Definition
rather than hysterectomy or oopherectomy, GnRH agonists can suppress estrogen production better via negative feedback. tx is 3-6 mos (longer than which, bone loss is a concern).
Term
is laparotomy in endometrial sx a failure?
Definition
no
Term
what characterizes sx for endometriosis?
Definition
sx is cytoreductive - not curative
Term
what are some examples of uterine adhesions, another source of pelvic pain?
Definition
omental adhesions/C-section scarring
Term
what characterizes uterine fibroids as a source of pelvic pain?
Definition
these are common (20-30% of women) and can cause inflammation/adhesion. they may be intramural/submucous/subserosal.
Term
what characterizes ovarian torsion as a source of pelvic pain?
Definition
peristalsis of the bowel can twist the ovaries - particularly w/PCOS
Term
what can omental adhesions cause in terms of pelvic pain?
Definition
PID
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