Term
|
Definition
| Spleen, Blood, Bone Marrow, Liver, Kidneys |
|
|
Term
|
Definition
| 90% water, 10% solutes (albumin, lytes, proteins) |
|
|
Term
| Protein contents in plasma |
|
Definition
| clotting factors, globulins, circulating antibodies, fibrinogen |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Chronic disease anemia patho |
|
Definition
| hemorrhage leads to cell loss while excessive fluid leads to dilution of RBC concentration |
|
|
Term
|
Definition
| a few days to a few weeks |
|
|
Term
|
Definition
| abnl % of neutrophils compared to total WBC |
|
|
Term
|
Definition
| Increase in # of circulating WBC often d/t infection |
|
|
Term
|
Definition
| Irregularly shaped, colorless, with sticky surface |
|
|
Term
|
Definition
| abnl decrease in # of platelets ex are sequestration, destruction (ITP), decreased production |
|
|
Term
|
Definition
| Deficiency of factor VIII |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Deficient component of factor VIII, generally is not serious |
|
|
Term
| Disseminated intravascular coagulation |
|
Definition
| results from cancer, sepsis, hypotension, OB complications, |
|
|
Term
|
Definition
| Cancerous disorder of plasma cells, pathologic fractures are common |
|
|
Term
|
Definition
| less than 5, more than 20 (nl 11-16) |
|
|
Term
|
Definition
| less than 15, more than 60 (nl is 35-44) |
|
|
Term
| Components of coagulation profile |
|
Definition
| Partial thromboplastin time, prothrombin time, platelet count, fibrinogen, platelet function analysis |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Done in posterior iliac crest when >3y old |
|
|
Term
| Transfusion reason packed RBC |
|
Definition
|
|
Term
| Transfusion reason fresh frozen plasma |
|
Definition
|
|
Term
|
Definition
| hemolytic, allergic, febrile |
|
|
Term
|
Definition
| immune response against transfused cells, antigens recognize foreign proteins stimulating B lymphocytes to produce antibodies |
|
|
Term
| In an allergic transfusion rxn, MD may order |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Products to treat hemophilia |
|
Definition
| fresh frozen plasma, cryoprecipitate, factor VIII, fibrin glue |
|
|
Term
|
Definition
| mixture of fibrinogen and thrombin, can be applied topically |
|
|
Term
|
Definition
|
|
Term
|
Definition
| thrombosis and hemorrhage occur, renal involvement=hematuria, pulmonary involvement, cutaneous involvement |
|
|
Term
|
Definition
|
|
Term
|
Definition
| antibodies destroy platelets, preceded by viral illness (flu, mono, varicella, URI, vaccine) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| older than 10 years, female |
|
|
Term
|
Definition
| IV gamma globulin 2-5 days to block antibody production, corticosteroids to enhance vascular stability, IV anti-D to stimulate platelet production |
|
|
Term
| sickling may be triggered by |
|
Definition
| fever and emotional or physical stress |
|
|
Term
|
Definition
| pain, splenomegaly, hemolytic crisis, stroke, kidney ischemia |
|
|
Term
|
Definition
| sudden and quickly progressing splenic enlargement, left upper quadrant pain vomiting |
|
|
Term
|
Definition
| trigger by virus or depletion of folc acid, diminished production and increased destruction of RBCs |
|
|
Term
| In bleeding disorders, demerol is contraindicated bc |
|
Definition
| increases the risk of seizures |
|
|
Term
|
Definition
| structural or quantitative abnlities in hemoglobin |
|
|
Term
|
Definition
| alpha or beta, depending on which part is lacking, cooley's anemia (severe) |
|
|
Term
| Thalassemia major cause of death |
|
Definition
| heart failure and infection |
|
|
Term
| Causes of aplastic anemia |
|
Definition
| exposure to drugs, chemicals, toxins, infection, idiopathic, Fanconi's |
|
|
Term
| Jaundice becomes visible when serum bilirubin levels |
|
Definition
|
|