Term
| Childhood cancers arise from which cell layer |
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Definition
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Term
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Definition
| Spontaneous bruising, prolonged fever, headaches in morning |
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Term
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Definition
| Type of cancer, location, extent of disease |
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Term
| Majority type of radiation therapy |
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Definition
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Term
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Definition
| Inhibits cells within the body to divide, leading to cell death |
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Term
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Definition
| PO, SQ, IM, IV, intrathecally |
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Term
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Definition
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Term
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Definition
| interfere with DNA production |
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Term
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Definition
| interferes with DNA production |
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Term
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Definition
| Prevent cells from dividing |
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Term
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Definition
| slow growth of some cancers |
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Term
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Definition
| hematopoietic stem cell transplant, involves umbilical cord blood and parent's stem cells |
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Term
| Cause of immunodeficiency in children with cancer |
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Definition
| lymphocyte production altered, splenic dysfunction (prevents maturation of WBCs), decreased immunoglobulin concentration |
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Term
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Definition
| Absolute neutrophil count decreases below 500 |
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Term
| Granulocyte colony stimulation factor (SQ) |
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Definition
| decreases duration of neutropenia by stimulation proliferation of progenitor cells of granulocytes (neutrophils) |
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Term
| Varicella immunization with exposure |
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Definition
| if child with no immunity has direct contact with a varicella individual, give immunization or acyclovir IV |
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Term
| Varicella immunization without exposure |
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Definition
| give three months after chemo, off prednisone |
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Term
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Definition
| Antiemetics, Trilafon, Thorazine, Phenergan block dopamine receptors from stimulating chemoreceptor trigger zones |
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Term
| Serotonin receptor antagonist |
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Definition
| Zofran, Kytril used when >3 years |
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Term
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Definition
| progressive inflammatory, ulcerative condition of oral gastric mucosa, occurs d/t interruption if cell renewal process |
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Term
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Definition
| Usually occurs within 10 days of chemo |
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Term
| Late effects of cancer therapy |
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Definition
| Sterility, thyroid, cardiovascular, respiratory |
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Term
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Definition
| Most common malignancy, cancer of blood or bone maarrow, usually WBCs, high survival rate |
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Term
| Acute Lymphoblastic leukemia |
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Definition
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Term
| Acute myelogenous leukemia |
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Definition
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Term
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Definition
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Term
| Chronic lymphocytic leukemia |
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Definition
| aalmost never affects children |
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Term
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Definition
| Initial WBC most significant, higher the count poorer the outcome (>100,000=poor) girls do better, under 2 over 10 |
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Term
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Definition
| Peripheral blood smear, bone marrow analysis, lumbar puncture |
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Term
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Definition
Induction: goal to achieve remission, 1 month
Consolidation: most intense, lasts 4-8 months
Maintenance: last 2-3 years |
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Term
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Definition
Cerebellar astrocytoma (50%)
Medullowblastoma
Brainstem glioma
ependymoma |
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Term
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Definition
| temozolamide, procarbazine, lomustine |
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Term
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Definition
| night sweats, weight loss, malaise, painless, firm nodes |
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Term
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Definition
| radiation to nodes, combo chemo for 6 months, prednisone, stem cell transplant |
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Term
| Neuroblastoma Age, survival, type of tumor |
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Definition
| 2 years, poorest survival rate, embryonic tumor |
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Term
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Definition
| CT or bone scan, 95% secrete catecholamines in the urine |
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Term
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Definition
| Most common intra-abdmonial/renal tumor in children, "silent" |
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Term
| Increased risk for Wilm's tumor |
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Definition
| Hypospadius, cryptorchidism, african american, femalse |
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Term
| Do not do this when assessing for Wilm's tumor |
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Definition
| DO NOT PALPATE THE ABDOMEN! |
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Term
| Osteogenic sarcoma metastasizes to: |
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Definition
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Term
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Definition
| tumor of flat bones (pelvis, chest, vertebrae) |
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Term
| Most common soft bone tissue tumor |
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Definition
| rhabdomyosarcoma (usually head and neck) |
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Term
| Intraocular tumor composed of embryonal retinal cells |
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Definition
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Term
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Definition
| strabismus, creamy white pupillary reflex, impaired vision, painful eyes, Cat eyes |
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