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Peds Test 1
Endocrine, Inborn Errors of Metabolism
36
Nursing
Graduate
05/27/2013

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Cards

Term
nl birthweight/length
Definition
6 lbs 2 oz to 9 lbs 2 oz
19 to 21 inches
Term
Hypophysis/Master gland
Definition
Pituitary
Term
Hormones of Posterior Pituiary
Definition
Oxytocin, vasopressin
Term
Diabetes Insipidus
Definition
Disorder of posterior pituitary, Inadequate ADH
Term
DI Causes
Definition
Hypothalamic lesion, craniotomy, idiopathic or familial
Term
First Sx od DI
Definition
Irritability, incessant crying, water will calm them
Term
Hypopituitarism/Growth Hormone Deficiency
Definition
Inhibits somatic growth, hypothalamus dysfunction
Term
GH deficiency clinical manifestations
Definition
Cherub facial features, frontal bossing, large eyes, button nose, small testes, look younger
Term
GH Deficiency Management
Definition
Biosynthetic growth hormone, thyroid extract, cortison.test and estrogens
Term
Creutzfeldt-Jakob Disease
Definition
Rare neurodegenerative condition reported in some patients after receiving human GH from cadavers
Term
Precocious Puberty
Definition
Girls: Breast development before 7.5 yrs
Pubic Hair: before 8.5 years
Menses: before 9.5 years
Boys: secondary sexual characteristics before age 9
Term
Tx of precocious puberty
Definition
LH is given monthly, decreases LH and FSH. Must be started prior to closure of epiphysis
Term
Delayed puberty
Definition
Girls: no breast development by 13, lack of menses within 5 yrs
Boys: secondary sex characteristics not started by 14 YOA
Term
Congenital reasons for delayed puberty
Definition
congenital adrenal hyperplasia
hypothyroidism
growth hormone deficiency
Term
Turner Syndrome
Definition
Females missing one x chromosome, diagnosed during puberty due to amenorrhea, low hair line, widely spaced nipples, edema of hands and feet
Term
Pituitary hyperfunction
Definition
Excess GH, overgrowth of long bones
Term
Acromegaly
Definition
Excess GH after epiphyseal closure
Term
Most common endocrine disorder of childhood
Definition
Juvenile hypothyroidism
Term
Clinical manifestations of juvenile hypothyroidism
Definition
decelerated growth, constipation, sleepiness, feeding difficulties, skin changes, periorbital edema, thick protruding tongue, large posterior fontanel
Term
Goiter (hypothyroidism)
Definition
Usually results from maternal ingestion of antithyroid medication during pregnancy
Term
Graves Disease
Definition
Most common cause of hyperthyroidism, enlarged thyroid gland and exopthalmos
Term
Graves Disease Tx
Definition
Propulthiouracil and methimazole (PTU, can cause Leukopenia)
Exercise restricted until levels are decreased or near normal (a-fib, CHF, tachy, brittle bones)
Term
Thyrotoxicosis
Definition
Thyroid Crisis; may occur from sudden release of hormone, unusual in children, but can be life threatening, Tx is antithyroid drugs
Term
Parathormone (PTH)
Definition
Maintains serum calcium
Term
Clinical Manifestations of hypoparathyroidism
Definition
dry, scaly skin with eruptions, brittle hair, thin nails with transverse grooves, positive Chvostek and/or Trousseau signs
Term
Hyperparathyroidism
Definition
Common factor is hypercalcemia, rare in children
Term
Adrenal Cortex hormones
Definition
Glucocorticoids, mineralcorticoids, sex steroids
Term
Acute Adrenocortical Insufficiency management
Definition
replacement of cortisol, body fluids, administer glucose solutions
Term
Chronic Adrenocorticol Insufficiency
Definition
rare in children, when it occurs usually the result of neoplasms. Sx appear after 90% of adrenal tissue is nonfunctional
Term
Addison Disease
Definition
Diagnosis based on replacement of cortisol and aldosterone
Term
Cushing Syndrome
Definition
caused by excessive circulating free cortisol
Term
Pediatric HTN
Definition
Consistently greater than 130/80
Term
Target BG levels
Definition
Toddler/preschool: 100-180
School age: 90-180
Adolescents: 90-130
Term
Acanthosis nigricans
Definition
hyperpigmentation and thickening of the skin into velvety irregular folds in the neck
Term
PKU
Definition
autosomal recessive defect found on chromosome 12
Term
PKU Tx
Definition
restrict protein intake.
maintain levels below 0.9 mmol/L, but at 0.2 for normal growth, avoid aspartame/Nutrsweet
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