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Peds Infections
KYCOM Block 11
105
Medical
Graduate
10/17/2013

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Term
define abscess
Definition
local collection of puss that becomes painful, warm, and tender
Term
what are the aerobic causes of abscess (5), what is the prevelence
Definition
50% aerobic
S. aureus 25%
GAS, strep, enterobacter, E. coli
Term
what are the anaerobic causes of abscess (2), what is the prevelence
Definition
25% anaerobic
bacteroides, fusobacterium
Term
what is the prevelence of a mixed, aerobic and anaerobic, abscess
Definition
25%
Term
what are the common causes of a perirectal abscess(4) and their prevelences
Definition
85% anaerobes
35% S. aureus
E. coli, strep
Term
what are the ddx of abscess, why
Definition
cellulitis: can progress to abscess
cyst: infected cyst is like an abscess
Term
what is lymphangitis, how can it be identified, what are the concerns
Definition
streaks showing infection moving through the lymph vessels
can get into blood and cause bacteremia and systemic infection
Term
what is the treatment for abscesses (3)
Definition
antibiotics, incision, drainage
Term
define adentitis
Definition
painful, hot, swollen node
Term
what do you do if you suspect adenitis (4)
Definition
look for source of the infection
if fluxcuant do aspiration
if purulent drain node
ultrasound may help determine
Term
what is paronychis
Definition
abscess caused by chewing on hangnail
Term
what are the overall most common, cervical, axillary, inguinal, and systemic causes of adenitis
Definition
overall tops: S. aureus, GAS

cervical: TB, influenza

Axillary: cat scratch, sporotrichosis

inguinal: anaerobes, enteric, plague

systemic: mono, toxoplasmosis, CMV, kawasaki, syphilis
Term
what are the two types of adenitis
Definition
lymphadenitis
mycobacterium adenitis
Term
what are the 4 signs of lymphadenitis
Definition
erythema
thin skin
fluctuance on palpation
central necrosis
Term
what are the 4 signs of mycobacterium adenitis
Definition
gradual node enlargement
little warmpth and iflammation
thick, discolored, tense, adherent skin
Term
what is the treatment for adenitis (3)
Definition
antibiotic trial
aspiration
drainage if fluctuant
Term
what do you do if the antibiotics for adenitis dont work
Definition
reactive adenitis would have resolved so consider persistant adenitis caused by Tb, cat scratch, mono, or malignancy
Term
what are the signs of bacteremia
Definition
infection without focus
Term
what do you do if you suspect bacteremia in a kid under 2 mo
Definition
full sepsis work up
Term
what do you do if you suspect bacteremia in a kid over 2 mo
Definition
bacteremia work up
Term
what are 5 causes of bacteremia and their prevelence
Definition
S. pneumoniae (90%)
influenza (10%)
salmonella, E. coli, S. aureus
Term
what are the parts to a bacteremia work up (5)
Definition
urinalysis
urine culture (males <6mo, females <2yo)
CXR
stool culture
blood culture with temp >39C
Term
what do you add to a bacteremia work up to make it a sepsis work up (3)
Definition
urine culture at any age
spinal tap
CBC
Term
what is the qualification for a fever of unknown origin
Definition
fever >100.4 at least twice a week for 3 weeks
at least one week of patient investigation without physical exam findings
Term
what is the initial work up for fever of unknown origiin (6)
Definition
history and physical
CBC
urinalysis and culture
CXR
TB test
ANA titer (autoimmune testing, in older kids)
Term
what is the work up in a return vision for fever of unknown origin (10)
Definition
CBC repeat
ESR
urinalysis and culture repeat
EBV screen
CXR review
blood culture
anti-streptolysin O
HIV antibody
Hep C antibody
twice daily temp recordings
Term
what is the initial work up for admitted fever of unknown origin (6)
Definition
LP (if antibiotics were unsuccessful or it is an infant)
blood culture repeat
sinus radiographs
opthalmic exam for iridocyclitis
liver enzyme test
multiple serologies
Term
what serologies might you do for an admitted fever of unknown origin patient (9)
Definition
CMV
toxoplasmosis
Hep A, B, C
tulaermia
brucellisis
leptospirosis
salmonellosis
Term
what is the work up for a inpatient fever of unknown origin after the first work up (7)
Definition
abdominal ultrasound
abdominal CT
gallium or indium scan
upper GI x-ray (older kid)
marrow test (if CBC abnormal)
techenium bone scan
Term
what is the most common pediatric infection
Definition
otitis media
Term
why is otitis media more common in kids (4)
Definition
eustachian tube is more horizontal and shorter because the cranium isnt completely developed
immune system isnt fully developed
they sick on thinks causing negative pressure
feeding supine allows entry of food near the eustachian tube
Term
what are the 3 layers of the TM
Definition
external epithelium
middle CT layer
inner respiratory ciliated epithelium
Term
contents of the middle ear and the boundries
Definition
ossicles
anterior: eustachian tube opening
lateral: TM
medial: connection to middle ear, nerves
posterior: opening to mastoid
superior: petrous bone
inferior: base of skull
Term
what are the signs of a ear infection (4)
Definition
painful, fever, minor head cold, fussy
Term
why is an ear infection painful
Definition
many nerve cells in the TM so when it stretches it causes lots of pain
Term
what are the signs in the TM of an ear infection
Definition
increased vasculature in pars flaxita that leats to erythemia
opaque
rirst retraction then bulging
reduced light reflex
landmarks obscured
mobility reduced due to fluid
Term
bullous otitis media: aka, define, 4 sings
Definition
myringitis

Ear infection due to unusual pathogen of childhood

Inflammation of epithelial layers causes excruciating pain

Bullous bleb blister like lesion obscures much of TM

Can rupture all three TM layers due to increased pressure spontaneously causing relief from pain and release of purelent goo
Term
two common causes of bullous otitis media
Definition
S. pneumo, myeloplasma
Term
most common cause of otitis media in non-immunized older kids
Definition
strep pneumonia
Term
most ocmmon cause of otitis media in immunized younger kids
Definition
influenza
Term
5 causes of otitis media common to least
Definition
strep pneumo 32%
non-pathogen (virus, allergies) 25%
influenza
moraxella, GAS
Term
5 complications of otitis media
Definition
fibrosis
conductive hearing loss
mastoiditis which can lead to meningitis or brain abscess
Term
main antibiotic used to treat otitis media
Definition
amoxicillin
TMP/SMX back up
Term
how do you determine to give antibiotics for otitis media
Definition
<6 mo give antibiotic

2mo – 2yo use judgment

2yo + wait 48 hours and give decongestant and anti-inflammatory first

If child looks sick use judgment at any age
Term
7 steps of otitis media treatment
Definition
1. antibiotics
2. If symptomatic 48 hours later change antibiotic
3. At 3 weeks if there is still effusion recheck in 3 weeks
4. At 6 weeks if there is still effusion change antibiotics
5. At 9 weeks if there is still effusion do tympanogram aor audiological testing. Add prednisone and give antibiotic with B-lactaminase resistance for 21 days
6. At 12 weeks if there is still effusion diagnose chronic otitis media, do tympanogram and audiological tests, refer to EENT
7. Tympanoscopy tubes: vent middle ear, improve hearing, reduce infection for patients with chronic otitis media
Term
what is the most comon cause of abscess
Definition
aerobic causes especially S. aureus
Term
what is the most common cause of lymphadenitis in axillary region
Definition
cat scratch
Term
what is the most common cause of general lymphadenitis
Definition
mono
Term
what are the two most common causes of bacteremia
Definition
S. pneumonia 90%
influenza 10%
Term
what is the most common cause of ear infection
Definition
strep pneumonia
Term
who gets acute sinusitis
Definition
kids >2yo
Term
5 signs of acute sinusitis
Definition
cough
nasal discharge
fever
facial pain
prolonged URI
Term
3 causes of sinusitis
Definition
strep pneumo
influenza
moraxella
Term
5 complications of sinusitis
Definition
cavernous sinus thrombosis
periorbital cellulitis
meningitis
maxillary osteomyelitis
brain abscess
Term
main cause of croup, 4 others
Definition
parainfluenza

influenza, RSV, adenovirus, pertussis
Term
croup aka
Definition
laryngitis
Term
what is the most common cause of upper airway obstruction in kids
Definition
crop
Term
what is croup
Definition
infection of the larynx
Term
what are 2 signs of croup
Definition
strier at rest
critical airway obstruction possible - epiglottis stenosis
Term
what is the at home tx for croup (3)
Definition
humidity
anti-pyretics
observation
Term
what is the hospital tx for croup (4)
Definition
humidity
recemic epinepherine
O2
deaxmethazone via intubation
Term
who gets broncholitis
Definition
2-10 mo
Term
broncholitis aka
Definition
laryngotrachelitis
Term
main cause of broncholitis, 2 more
Definition
main is RSV

adenovirus, parainfluenza
Term
3 signs of broncholitis
Definition
high TT
subcostal movement
wheeze
Term
1 complication of broncholitis
Definition
COPD
Term
tx broncholitis (2)
Definition
bronchodilator B2 agonist (albuterol)
oxygen as needed
Term
11 reasons to use ribivirin for RSV
Definition
complicated congenital heart disease
congenital abnormalities

premature baby
under 6wks

bronchopulmonary displasia
cystic fibrosis
on ventilator

immune deficient
transplant patient
cancer patient
severly ill patient
Term
who gets pneumonia
Definition
2% of infants <1yo
4% of children 1-5yo
Term
what is pneumonia
Definition
inflammation and infection of alveola and pleura
Term
4 symptoms of pneumonia
Definition
chest pain on cough
wet cough
crackles
Term
when do you admit pneumonia patient (8)
Definition
hypoxia, accessory muscle use, effusion

<3mo, <3yo with lobar, <5yo with multiple lobar

chronic diseasse

progression during treatment
Term
what are chronic diseases that you should admit the patient if you suspect pneumonia (8)
Definition
CF
malignancy
anemia
diabetes
cardiac
pulmonary
renal
immune disorder
Term
what is the diagnostic test for pneumonia
Definition
CXR confirms
can be treated off of clinical signs too (crackles)
Term
how is pneumonia treated in a pt <3mo, <20 wk, >5yo, 10-20yo
Definition
<3mo: IV ampicillin, cephtriaxone

<20wks: add erythromycin (to cover chalmydia)

>5yo: amoxicillin, IV amoxicillin and cephtriaxone if serious

10-20: add macrolide (erythromycin) to cover mycoplasm walking pneumonia
Term
who gets UTI
Definition
girls are at higher risk
uncurcumsized boys
kids are at greater risk
Term
what is the general concept of the cause of UTI
Definition
inadequate wash oout and increased adherence of bacteria
Term
what are 9 risk factors for uti
Definition
urothelial deficiency
hydronephrosis
obstruction
nephrolithiasis
vesicoureteral reflux
catheter or foreign body
non-retractable foreskin
fecal incontinence
poor hygiene
Term
what is the number one and 2 cause of uti
Definition
E. coli 80%
klebsiella
Term
what is the number 1 cause of uti in boys, why
Definition
poteus seen in 30% of boys under foreskin
Term
what is a common cause of uti in aldolecence
Definition
staph saphrophyticus
Term
what are 3 uncommon causes of uti
Definition
pseudomonas
enterococcus
staph aureus
Term
what are 5 signs of uti
Definition
cystitis
foul smelling urine
fever
chills
accidents after potty training
Term
what is cystitis (3)
Definition
dysuria (pain), frequency, enuresis
Term
what is a complication of uti
Definition
develop renal scaring if they get more than 1 uti
Term
how is urine collected for a uti sample
Definition
pee in cup unless 2mo - 2yo then use suprapubic collection
Term
what do you need to remember when culturing for UTI
Definition
get repeat sample so asymptomati bacteriria can be detected
Term
what is tested for from a urine sample (7)
Definition
WBC
leukocyte esterase
nitrite
bacteria
WBC casts
serum CRP
Term
how many WBC is too much in urine
Definition
>10
Term
why might someone have a uti and not have nitrite
Definition
urine isnt concentrated enough, bacteria isnt the kind that makes it (like pseudomonas)
Term
how much bacteria is diagnostic for uti
Definition
>50,000 CFU/mL to confirm
any bacteria in a urine aspiration
Term
what do casts in urine indicate
Definition
if WBC: uti or pyelonephritis
PMN or tamm horsfall are ok becase they prevent bacterial adherence
Term
why do we check serum CRP in uti check
Definition
it can be increased in pyelonephritis
Term
first antibiotic for uti, 3 runner ups, how long is the perscription
Definition
tmp/smx

amoxicillin, sulfisoxazole, cephalosporins

7-12d
Term
what group needs a different antibiotic redigmen for uti, why
Definition
infants <60 days old
need to cover enterococci and liseria
Term
what is the concern with uti antibiotic tx
Definition
elimination of bacteria with low virulence can cause overgrowth and more agressive strains
Term
how do you treat someone long term uti with vesicureteral reflux
Definition
if they do surgery do prophylaxis until resolution of the problem

if they dont do prophylaxis until 10 yo or until resolution
Term
how do you treat chronic uti in someone without vesicureteral reflux
Definition
look into other GI problems
if you find something continue prophylaxis for 1year
if you dont continue for 6mo
Term
what GI problems can cause chronic uti without vesicureteral reflux (4)
Definition
obstructive uropathy
neurigenic bladder
ureter duplication
calculi
Term
5 signs of pyelonephritis
Definition
high fever
flank pain
vomiting
elevated WBC and ESR
Term
tx pyelonephritis
Definition
cephalosporins (cephtriazone)
Term
what can cause uti symptoms without bacteria (11)
Definition
Urethritis, vulvovaginitis, balanitis, pinworm

Metal irritation, topical irritants (soap, loation), vaginal foreign body

medication, emotional stress, trauma (sexual), daytime frequency syndrome
Term
what is pyuria
Definition
urine with puss
Term
what can cause pyuria without bacteria
Definition
• Urine with puss
• Febrile systemic illness
• Concentrated urine
• Catheter or instrument irritation
• Inflammation
• Calculi
• Glomerulonephritis
• Interstitial nephritis
• Nonbacterial infection: candidia, Mycobacterium TB, ureaplasma
Term
describe the 5 grades of vesicuoreteral reflux
Definition
• Grade 1: cystourethrogram shows reflux only into ureter
• Grade 2: complete reflux into ureter, pelvis and calyces
• Grade 3: complete reflux and mild dilation of ureter and renal pelvis, only slight calyces
• Grade 4: reflux with moderate dilation of all parts, oblideration of sharp angle fornices
• Grade 5: dilation of all parts and oblideration of papillary impressions of calyces
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