Term
| occur promptly after the sensitized individual is exposed to an antigen and are mediated by specific IgE antibodies. Ex = allergic rhinitis, urticaria |
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Definition
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Term
| Involve antibodies directed against antigenic components of peripheral blood or tissue cells, or foreign antigens, resulting in cell destruction. Ex = autoimmune hemolytic anemia, Rh and ABO hemolytic disease of the newborn, Goodpasteur syndrome |
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Definition
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Term
| antigen-antibody complexes form and are deposited in the lining of blood vessels, stimulating tissue inflammation mediated by complement or activated white blood cells. Ex = serum sickness, the immune-complex-mediated renal diseases |
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Definition
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Term
| Involve T-Cell mediated tissue inflammation and typically occur 24-48 hours after exposure. Ex = PPD reactions, contact dermatitis |
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Definition
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Term
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Definition
| avoidance of offending allergens, environmental measures, antihistamines, nasal cromalyn, nasal corticosteroids, immunotherapy |
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Term
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Definition
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Term
atopic dermatitis distribution:
infants
children |
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Definition
infants = cheeks, trunk, hands, feet, extremities (extensor)
children = hands, feet, extremities (flexural) |
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Term
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Definition
| avoid known triggers and fragrant soaps, good skin care and hydration, soap substitutes, mild superfatted soaps, Burrow's solution (Aveeno), lubrican skin post bath, corticosteroids, antibiotics |
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Term
| moisturizes used for atopic dermatitis |
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Definition
| ointments (aquaphor), creams (eucerin), lotions (neutroderm) |
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Term
| antihistamines used in atopic dermatitis |
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Definition
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Term
| corticosteroid creams used in atopic dermatitis |
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Definition
| hydrocortisone, fluticasone, mometasone |
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Term
| abx used in atopic dermatitis |
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Definition
| cephalexin, dicloxacillin |
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Term
| what is the most common precipitnats of acute asthma in children? |
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Definition
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Term
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Definition
| smoking, strong emotions, furry pets, exercise, colds, pollen, change in weather, cockroaches, food, mold/mildew, dust, cold weather, strong smells |
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Term
| asthma with onset in children/adolescents, FHx usually +, skin test +, triggers related to specifc antigens, hx of eczema, allergic shiner, cough may be predominant response in children, favorable response to hyposensitization, IgE mediated |
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Definition
| extrinsic (allergic) asthma |
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Term
| how does extrinsic asthma response to tx? |
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Definition
| usually well, may become chronic. May improve mid-adolescence but usually recurs in adulthood |
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Term
| onset in adulthood (>35yo), FHx-, triggers related to infections or exercise, no hx of eczema, skin test -, no response to hyposensitization, dyspnea on exertion |
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Definition
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Term
| prognosis of intrinsic astham |
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Definition
| more chronic and severe than extrinsic asthma requiring more extensive tx. More often corticosteroid dependent |
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Term
| reasons for poor asthma control |
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Definition
inhaler technique, compliance, environmental changes.
consider another diagnosis.
consider increasing long-term therapy doses. |
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Term
sxs < or equal to 2d/wk
nighttime awakening < 2x/month
SOBA use < or equal to 2d/wk
Interference with ALD = none
Normal FEV1 between exacerbations, FEV1>80% predicted, FEV1/FVC > 85% |
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Definition
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Term
sxs > 2d/wk but not daily
nighttime awakening 3-4x/month
SOBA use >2d/wk but not daily
mild limitation of ADLs
FEV1 > or equal to 80%
FEV1/FVC > 80% |
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Definition
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Term
sxs daily
nighttime awakening > 1x/wk but not nightly
SOBA use > 2 d/wk but not daily
some limitation of ADLs
FEV1 = 60-80%
FEV1/FVC = 75-80% |
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Definition
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Term
sxs throughout the day
nighttime awakenings often 7x/wk
SOBA use several times/day
ADLs = extremely limited
FEV1 < 80%
FEB1/FVC < 75% |
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Definition
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Term
| tx of intermittent astham |
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Definition
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Term
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Definition
preferred = low dose ICS
alternative = cromalyn, LTRA, nedocromil, or theophylline |
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Term
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Definition
consider asthma specialist consult.
preferred = low dose ICS + either LABA, LTRA or theophylline OR medium dose ICS |
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Term
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Definition
consult with asthma specialist
preferred = medium dose ICS + LABA
alternative = medium dose ICS + either LTRA or theophylline |
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Term
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Definition
consult asthma specialist
preferred = high dose ICS + LABA
alternative = high dose ICS + LTRa or theophylline |
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Term
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Definition
consult asthma specialist
preferred = High dose ICS + LABA + oral systemic corticosteroid
alternative = high dose ICS + either LTRA or Theophylline + oral systemic corticosteroid |
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Term
asthma control 5-11:
sxs >2d/wk or multiple times on <2d/wk
nighttime awakening >2x/month
some limitation of ADLs
SOBA use >2d/wk
FEV1 = 60-80% predicted
FEV1/FVC = 75-80% |
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Definition
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Term
asthma control 5-11:
sxs < 2d/wk but not more than once on each day
nighttime awakening <1x/month
no interference with ADL
SOBA use <2d/wk
FEV1 >80% predicted/personal best
FEV1/FVC > 80% |
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Definition
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Term
asthma control 5-11yo
sxs throughout the day
nighttime awakening >2d/wk
ADLs = extremely limited
SOBA use several times/day
FEV1 <60% predicted
FEV1/FVC <75% |
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Definition
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Term
|
Definition
6-11yo = <200mcg/d
12+ = <250mcg/d |
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Term
| medium dose corticosteroids |
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Definition
6-11 = 201-400mcg/day
12+ = 251-500mcg/day |
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Term
| high dose corticosteroids |
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Definition
6-11 = >400mcg/day
12+ = >500mcg/day |
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