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PD: genetics
behavioral vs molecular
10
Psychology
Graduate
10/16/2012

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Cards

Term
behavioral genetics research questions
Definition
1950s- ask questions why are we all different, why are children like their parents, why are children of the same parents so different? what is the variation in the individual and the covariation between relatives?
Term
behavioral genetics methods (humans)
Definition
twin/family/adoption studies- attempts to ID causal effects as a natural way to control for other genes and environment; ID hereditability (range, i.e. IQ= 50-80%)
Term
behavioral genetics interaction and correlation
Definition
interaction- genetic sensitivity (w/in ind. and at different devl. times)
correlations: active, passive, evocative
Term
behavioral genetics methods (animals)
Definition
inbred strain comparison, selective breeding- can know how much you influence trait/ genes, can't know this with humans
Term
molecular genetics
Definition
1980s- additive, dominant, epistatic
Term
MG- linkage analyses
Definition
affected individual and family are more likely to have certain gene- mostly small alleles with little effect, many alleles in a single trait, disequilibrium
Term
association analyses
Definition
gene variant exists more in affected than non-affected, specific gene in small region, tend to be indirect (ie blue family are few that are direct)
Term
candidate gene
Definition
GWAS0 no selection bias, cost effective
Term
problems with molecular genetics
Definition
most studies have looked at 5HTTLPR, MOAI, LPR, Taq1A genes, expensive (although getting less expensive)
Term
problems with behavioral genetics
Definition
heredity is range, not precise number
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