Term
| Ketamine is an NMDA receptor ____. |
|
Definition
|
|
Term
| ______ is an NMDA antagonist used in anesthesia. |
|
Definition
|
|
Term
| PCP is an NMDA receptor _____. |
|
Definition
|
|
Term
| This sometimes recreational drug is an NMDA receptor antagonist: |
|
Definition
|
|
Term
| ____ is an NMDA receptor antagonist that is sometimes used as a recreational drug. |
|
Definition
|
|
Term
| This NMDA receptor antagonist was once used as an anesthetic, but has been phased out. |
|
Definition
|
|
Term
| Vigabatrin inhibits _____ _____, an enzyme that metabolizes GABA. |
|
Definition
|
|
Term
| Vigabatrin is clinically used to treat: |
|
Definition
|
|
Term
| This drug enhances GABA by inhibiting GABA metabolism: |
|
Definition
|
|
Term
| This GABA analog is sometimes used to treat seizures: |
|
Definition
|
|
Term
| This GABAb receptor agonist is used to treat Huntington's Disease: |
|
Definition
|
|
Term
| Baclofen, a ____ receptor agonist, is used clinically to treat___. |
|
Definition
| GABAb; Huntington's Disease |
|
|
Term
| Baclofen is a GABAb receptor _____ used to treat _____. |
|
Definition
| Agonist; Huntington's Disease |
|
|
Term
| Picrotoxin acts as a GABAa receptor ____. |
|
Definition
|
|
Term
| Picrotoxin is a ___-convulsant. |
|
Definition
|
|
Term
| Picrotoxin, a GABAa antagonist, ____ the opening frequency and mean open time of _____. |
|
Definition
|
|
Term
| This drug decreases the opening frequency and mean open time of Cl- channels. |
|
Definition
| Picrotoxin or Bicuculline |
|
|
Term
| Bicuculline acts as a ___-convulsant. |
|
Definition
|
|
Term
| Bicuculline, a GABAa receptor antagonist, ____ the opening frequency and mean open time of _____. |
|
Definition
|
|
Term
| Bicuculline, a GABAa receptor antagonist, decreases ______ and mean ______ of Cl- channels. |
|
Definition
| Opening frequency; mean open time |
|
|
Term
| This drug is a glycine receptor antagonist: |
|
Definition
|
|
Term
| Strychnine is a ______ receptor ____. |
|
Definition
|
|
Term
| Strychnine prevents ____ from entering the neuron inhibiting the _________. |
|
Definition
| Cl-; Inhibitory Post-Synaptic Potential (IPSP) |
|
|
Term
| _______ prevents Cl- from entering a neuron, inhibiting Inhibitory Post-Synaptic Potential. |
|
Definition
|
|
Term
| Diazepam is clinically used as a(n): |
|
Definition
| Anxiolytic, anti-convulsant, and sedative (long-acting) |
|
|
Term
| Alprazolam is clinicatlly used as a(n): |
|
Definition
| Anxiolytic, antidepressant |
|
|
Term
|
Definition
|
|
Term
| Temazepam is used as a _______ sedative and to induce ______. |
|
Definition
|
|
Term
| Triazolam is used as a ______ sedative and for re-occuring_______. |
|
Definition
|
|
Term
| Clonazepam is used as a(n): |
|
Definition
|
|
Term
| Buspirone is a _______ at the _______. |
|
Definition
| Partial agonist; 5HT1A receptor |
|
|
Term
| Buspirone is used as a(n)_________ with a (slow/fast) onset of action. |
|
Definition
|
|
Term
| Flumazenil is a benzodiazepine ________, used to treat___________. |
|
Definition
| Antagonist; benzodiazepine over-dose |
|
|
Term
| Phenobarbital is a (short/intermediate/long)-acting barbiturate. |
|
Definition
|
|
Term
| Phenobarbital is a long-acting barbiturate used to treat: |
|
Definition
|
|
Term
| Pentobarbital is a (short/intermediate/long)-acting barbiturate. |
|
Definition
|
|
Term
| Thiopental is a (short/intermediate/long)-acting barbiturate. |
|
Definition
|
|
Term
| Thiopental is clinically used as a(n): |
|
Definition
|
|
Term
| Paroxetine is an example of a: |
|
Definition
| Selective Serotonin Reuptake Inhibitor |
|
|
Term
| Paroxetine is used to treat: |
|
Definition
|
|
Term
| Venlafaxine XR acts by _________ and blocking _________. |
|
Definition
| Inhibition of serotonin reuptake; norepinephrine transporter |
|
|
Term
| Venlafaxine XR is used to treat: |
|
Definition
|
|
Term
| Zolpidem is classified as a: |
|
Definition
|
|
Term
| Zolpidem acts on the same receptors as: |
|
Definition
|
|
Term
| Zolpidem acts on _____ receptors. |
|
Definition
|
|
Term
| Zolpidem is used to treat: |
|
Definition
|
|
Term
| Zolpidem is the generic name for this brand drug: |
|
Definition
|
|
Term
| Eszopiclone is clinically used to treat: |
|
Definition
|
|
Term
| Unlike other sedative-hypnotics, eszopiclone is safe to use in what specific demographic groups? |
|
Definition
| Elderly and younger adults |
|
|
Term
| Eszopiclone is the generic name for this brand name: |
|
Definition
|
|
Term
| Eszopiclone is the generic name for this brand name drug: |
|
Definition
|
|
Term
| Ramelteon acts as a ________ agonist. |
|
Definition
|
|
Term
| Unlike zolpidem, ramelteon is not a ________. |
|
Definition
|
|
Term
| Ramelteon is the generic name for this drug: |
|
Definition
|
|
Term
| If you are missing your dreams about Abraham Lincoln and beavers, you should probably________. |
|
Definition
| Be put on ramelteon or seriously consider why you would be dreaming about Abraham Lincoln or beavers. |
|
|
Term
| This drug is a sedative-hypnotic that is known to cause distinct GI stress: |
|
Definition
|
|
Term
| Hydroxyzine is an ____________ used in patients with _______. |
|
Definition
| Antihistamine; history of addiction to sedatives, etc. |
|
|
Term
| Ethyl alcohol acts as a(n): |
|
Definition
| Anxiolytic, sedative, reason to look forward to Thursdays |
|
|
Term
| Atomoxetine is a selective ____. |
|
Definition
| (selective) NE reuptake inhibitor |
|
|
Term
| Strattera is the brand name for which drug? |
|
Definition
|
|
Term
| Atomoxetine is clinically used to treat: |
|
Definition
|
|
Term
| Cocaine inhibits ____ and ____. |
|
Definition
|
|
Term
| Ondansetron is a ________ receptor ________. |
|
Definition
| 5-HT3 receptor antagonist |
|
|
Term
| The Area Postrema controls: |
|
Definition
|
|
Term
| Ondansetron antagonists 5-HT action in the _______ of the medulla. |
|
Definition
|
|
Term
| Ondansetron is clinically used as an: |
|
Definition
|
|
Term
| Galantamine is a ____ inhibitor used to treat AD. |
|
Definition
|
|
Term
| Razadyne is the trade name of this ChE inhibitor used to treat AD. |
|
Definition
|
|
Term
| Galantamine promotes longer duration of ACh in the synaptic cleft by inhibiting: |
|
Definition
|
|
Term
| Exelon is the trade name of this drug used to treat AD: |
|
Definition
|
|
Term
| Rivastigmine is a cholinesterase inhibitor used to treat: |
|
Definition
|
|
Term
| Galantamine is a cholinesterase inhibitor used to treat: |
|
Definition
|
|
Term
| Rivastigmine is a ___ inhibitor used to treat AD. |
|
Definition
|
|
Term
| Aricept is the trade name of this drug used to treat AD: |
|
Definition
|
|
Term
| Donepezil is a _____ inhibitor used to treat AD. |
|
Definition
|
|
Term
| Donepezil promotes longer duration of ACh by: |
|
Definition
|
|
Term
| Namenda is the trade name of this drug used to treat AD. |
|
Definition
|
|
Term
| Memantine is an ______ used to reduce excitotoxicity, prolonging the life of neuronal cells. |
|
Definition
|
|
Term
| Memantine is an ________ used in conjunction with ChE inhibitors to treat AD. |
|
Definition
|
|
Term
| This drug is a precursor to DA that crosses the BBB and is converted to DA. |
|
Definition
|
|
Term
| Levodopa is clinically used to treat: |
|
Definition
|
|
Term
| Unlike DA, levodopa crosses the _____. |
|
Definition
|
|
Term
| Carbidopa inhibits ______ metabolism, increasing its effectiveness. |
|
Definition
|
|
Term
| Carbidopa does not cross the BBB, allowing for lower doses of: |
|
Definition
|
|
Term
| Carbidopa is used in conjunction with levodopa to treat: |
|
Definition
|
|
Term
| Sinemet is a combination drug of: |
|
Definition
|
|
Term
| Levodopa and carbidopa is marketed as a combo drug called: |
|
Definition
|
|
Term
| Sinemet is the gold standard therapy in the treatment of: |
|
Definition
|
|
Term
| Bromocriptine is a ____ used to induce normal DA effects in PD patiets. |
|
Definition
|
|
Term
| This drug is a DA agonist used to induce normal DA effects in PD patients: |
|
Definition
|
|
Term
| Bromocriptine is clinically used to treat: |
|
Definition
|
|
Term
| Pergolide is a _____ used to induce normal DA effects in PD patients. |
|
Definition
|
|
Term
| Pergolide is clinically used to treat: |
|
Definition
|
|
Term
| Amantadine is clinically used to treat: |
|
Definition
|
|
Term
| This drug used to treat PD is thought to sensitize DA receptors: |
|
Definition
|
|
Term
| Deprenyl (L-Deprenyl) is the trade name for this MAOI: |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Selegiline inhibits ____, avoiding a potential hypertensive crisis. |
|
Definition
|
|
Term
| Selegiline, an MAO-B inhibitor acts by: |
|
Definition
| Prolonging the existence of DA in the synaptic cleft |
|
|
Term
| Selegiline is an MAO-B inhibitor used to treat: |
|
Definition
|
|
Term
| Entacapone is a ______ used in patients with PD. |
|
Definition
|
|
Term
| This COMT inhibitor increases the concentration of DA in the syaptic cleft. |
|
Definition
|
|
Term
| Entacapone is clinically used to treat: |
|
Definition
|
|
Term
| This drug is a combination product of Sinemet and entacapone used to treat PD. |
|
Definition
|
|
Term
| Stalevo and MAOIs may cause: |
|
Definition
|
|
Term
| Benztropine is a _____ used to decrease the release of ACh and treat PD. |
|
Definition
|
|
Term
| This drug is a mAChR antagonist used to treat PD: |
|
Definition
|
|
Term
| This drug is given to PD patients with past histories of abuse, DA disorders, psychological disorders, or anything contraindicated by DA enhancing drugs. |
|
Definition
|
|
Term
| Trihexyphenidyl is a _____ used to treat PD. |
|
Definition
|
|
Term
| Trihexyphenidyl is a mAChR antagonist clinically used to treat: |
|
Definition
|
|
Term
| Haloperidol is a ___ used in the treatment of Huntington's Disease. |
|
Definition
|
|
Term
| This DA antagonist is clinically used to treat Huntington's Disease. |
|
Definition
|
|
Term
| This DA antagonist used to treat Huntington's Disease decreases hyper-responsiveness of DA neurons. |
|
Definition
|
|
Term
| This GABA-B receptor agonist is used primarily to reduce muscle movements and spasticity in patients with Huntington's Disease. |
|
Definition
|
|
Term
| Baclofen is a _____ used to treat dyskinesia associated with Huntington's Disease. |
|
Definition
|
|
Term
| This corticosteroid is used to supress T-cells and inflammation in MS patients. |
|
Definition
|
|
Term
| This drug therapy suppresses T-cell proliferation, enhances BBB function, and reduces BBB permeability: |
|
Definition
|
|
Term
| Interferon-beta is used in the treatment of: |
|
Definition
|
|
Term
| This drug therapy reduces access of T-Cells to the brain in MS patients: |
|
Definition
|
|
Term
| Copaxone is the trade name for this MS drug. |
|
Definition
|
|
Term
| Glatiramer acetate is clinically used to treat: |
|
Definition
|
|
Term
| Glatiramer acetate's MOA in treating MS: |
|
Definition
| Reduce the effects of T-cells degrading myelin shethes |
|
|
Term
| This anti-neoplastic agent is used in the treatment of MS. |
|
Definition
|
|
Term
| Novantrone is the trade name of this drug: |
|
Definition
|
|
Term
| Mitoxantrone ______ to treat MS. (MOA) |
|
Definition
| Suppresses T-cells and B-cells |
|
|
