Term
| These types of drugs decrease sympathetic neuronal activity: |
|
Definition
|
|
Term
| Phenoxybenzamine and phentolamine are examples of: |
|
Definition
| Non-selective alpha-blocking drugs |
|
|
Term
| Prazosin and yohimbine are examples of: |
|
Definition
| Selective alpha-blocking drugs |
|
|
Term
| These types of drugs block the action of norephinephrine and epinephrine, causing vasodilation and a decrease in blood pressure: |
|
Definition
|
|
Term
| These receptors are predominant on vascular smooth muscle: |
|
Definition
|
|
Term
| Alpha-1 blockade can result in these response reflexes: |
|
Definition
| Reflex tachycardia; postural hypotension |
|
|
Term
| This condition is a sudden drop in blood pressure due to the effects of gravity: |
|
Definition
|
|
Term
| This drug is an IRREVERSIBLE, non-selective alpha receptor blocker: |
|
Definition
|
|
Term
| This non-selective, irreversible alhpa blocker is used to treat pheochromocytoma: |
|
Definition
|
|
Term
| Phenoxybenzamine is used in the treatment of: |
|
Definition
|
|
Term
| This drug is a potent competitive REVERSIBLE, non-selective alpha blocker: |
|
Definition
|
|
Term
| This competitive reversible, non-selective alpha blocker is used to treat pheochromocytoma: |
|
Definition
|
|
Term
| Phentolamine is clinically used to treat: |
|
Definition
|
|
Term
| This drug is a potent alpha-1 receptor antagonist: |
|
Definition
|
|
Term
| This selective alpha-1 antagonist is used to treat severe cases of chronic hypertension: |
|
Definition
|
|
Term
| This drug is a selective alhpa-2 receptor antagonist: |
|
Definition
|
|
Term
| This selective alpha-2 antagonist is clinically used to treat male impotence: |
|
Definition
|
|
Term
| Postural hypotension, reflex tachycardia, inhibition of ejaculation, and nasal stuffiness are side effects of: |
|
Definition
|
|
Term
| Propranolol and timolol are examples of: |
|
Definition
| Non-selective B-antagonists |
|
|
Term
| These drugs competitively block the effects of Epi/NE: |
|
Definition
|
|
Term
| Beta-1 blockers are clinically used to treat: |
|
Definition
|
|
Term
| The term chronotropic refers to: |
|
Definition
|
|
Term
| The term inotropic refers to: |
|
Definition
|
|
Term
| This drug is a non-selective beta antagonist that causes blocks positive chronotropic (heart rate) and inotropic (contractility) effects on the heart: |
|
Definition
|
|
Term
| This non-selective beta blocker is used to treat HTN, angina, arrhythmia, post-MI, etc. |
|
Definition
|
|
Term
| Side effects of propranolol in asthma patients includes: |
|
Definition
| Worsening of asthma symptoms because of Beta-2 antagonism |
|
|
Term
| Side effects of propranolol in diabetics includes: |
|
Definition
| Insulin induced hypoglycemia; inhibition of gluconeogenesis and glycogenolysis |
|
|
Term
| Propranolol is contraindicated in heart disease patients with which diseases? |
|
Definition
| Sinus bradycardia, partial heart block, congestive heart failure |
|
|
Term
| True or False: Patients who take propranolol for extended periods of time are at risk for rebound effects/withdrawal. |
|
Definition
|
|
Term
| Timolol is an example of this type of drug: |
|
Definition
| Non-selective B-antagonist |
|
|
Term
| This non-selective B-antagonist is used clinically to treat HTN, angina, and topically to treat glaucoma: |
|
Definition
|
|
Term
| Timolol, a non-selective B-antagonist, is clinically used to treat what? |
|
Definition
| HTN, angina, and topically to treat glaucoma |
|
|
Term
| Atenolol, bisoprolol, and metoprolol are examples of: |
|
Definition
|
|
Term
| Which of these should be administered to a patient with hypertension and asthma: metoprolol or propranolol? |
|
Definition
|
|
Term
| These drugs have greater affinity for beta receptors in the heart and cause a decrease in heart rate and contractility: |
|
Definition
|
|
Term
| Acute bronchospasm, bradycardia, and withdrawal symptoms are all possible side effects with these drugs: |
|
Definition
|
|
Term
| Beta-1 antagonists are clinically used to treat what diseases: |
|
Definition
| HTN, angina, heart failure, migraine prophylaxis (metoprolol and atenolol), and tremor (metoprolol) |
|
|
Term
| This class of drugs is used to inhibit the synthesis, storage, and release or norepinephrine: |
|
Definition
| Indirect-acting sympatholytic drugs |
|
|
Term
| Indirect-acting sympatholytic drugs are primarily used to treat: |
|
Definition
|
|
Term
| Metyrosine inhibits this enzyme: |
|
Definition
|
|
Term
| The inhibition of tyrosine hydroxylase by this drug inhibits the production of dopamine, NE, and Epi: |
|
Definition
|
|
Term
| This drug used in the treatment of HTN associated with pheochromocytoma inhibits the release of Epi/NE. |
|
Definition
|
|
Term
| Carbidopa decreases the release of dopamine by inhibiting this enzyme: |
|
Definition
|
|
Term
| This drug is given in conjunction with L-Dopa to increase L-Dopa's bioavailability: |
|
Definition
|
|
Term
| Carbidopa, along with L-Dopa, is used in the treatment of this disease: |
|
Definition
|
|
Term
| This drug is used with low dose diuretics to treat mild HTN: |
|
Definition
|
|
Term
|
Definition
| Decreasing the storage of NE in storage vesicles |
|
|
Term
| This drug decreases the release of NE, and has been discontinued in the US: |
|
Definition
|
|
Term
| Guanethidine, like tyramine, displaces this molecule: |
|
Definition
|
|
Term
| Guanethidine, which is discontinued in the US, can cause these side effects: |
|
Definition
| Decreased BP, HR, & CO; postural hypotension; increased gut motility & MASSIVE DIARRHEA; nasal stuffiness; impaired ejaculation. |
|
|
Term
| Bretylium is clinically used as: |
|
Definition
| An IV treatment of ventricular dysrhythmias |
|
|
Term
| This drug decreases the release of NE, and blocks NE reuptake: |
|
Definition
|
|
Term
| Methyldopa and clonidine are alhpa-2 agonists that do what? |
|
Definition
| Decrease sympathetic outflow in the CNS |
|
|
Term
| Activation of alpha-2 receptors in the hypothalamus and medulla by these drugs causes an increase in sympathetic outflow from the CNS. Consequentially, this decreases the total peripheral resistance, heart rate, and cardiac output, leading to a reduction in blood pressure. |
|
Definition
|
|
