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PCOL SEM1
ANS
5
Pharmacology
Undergraduate 2
09/12/2010
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Cards

Term

Muscarinic receptors:

M1 act on what in the body?

M2 ?

M3 ?

 Definition

M1 CNS; Stomach (gastric parietal cells)

 

M2: CNS ; Heart; Smooth Muscle mss.

 

M3: Exocrine glands; bladder; Smooth Muscle mss.; blood vessels (endothelium)
Term
the antidote to Atropine (which crosses the BBB)  overdose is?
 Definition
Phyostogmine or pilocarpine
Term

In organophosphate poisoning symptoms include  (Sludge)

(Salivation, Lacrimation, Urination, Diaphoresis, Gastrointestinal motility, Emesis)

What drug can you treat this with?

 Definition

 

 

Atropine
Term
Atripine Toxcity = what effects
 Definition

 

Xerostomia; Mydriasis; Blurred vision; Tachycardia; Hot Flushed skin; Agitation; Delirium; Hallucination; Excitation; Rapid respiration followed by depression (respiratory failure death)
Term

 

 

 

 

Name the types of drugs that are

parasympathomimetic

 Definition

Muscarinic Agonists

(a) Achetylcholine & Choline esters (Bethancol & Carbachol)

     (b) Cholinomimetic alkaloids (Pilocarpine)

 

1.2. Anticholinesterases 

Short - Edrophonium (tensilon)

Med - Phyostigmine, Neostigmine,Pyridostigmine

Long - Dyflos, parathion, Ecothiopate

1.3. Nicotinic Agonists -Nicotine, Lobeline, Anticholinesterases
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