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Pathophysiology
Ch 39 Disorders of the Integument
28
Health Care
Undergraduate 2
09/09/2008

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Cards

Term
Alopecia: Male & Female
Definition
hair loss
Male: inherited, irreversible, loss in central scalp
Female: thinning of central hair (onset 20-20years old)
Term
1st Degree Burn
Definition
Superficial skin(Only epithelial)- no loss of protective function
Term
2nd degree burn: Partial-thickness & Deep-thickness
Definition
Partial- destruction of epidermis and some dermis. Blister formation and pain.
Deep- destruc. of epidermis and dermis. appear waxy. takes weeks to heal.
Term
3rd degree burn
Definition
Destruction of epidermis, dermis, and subcutaneous tissue. Bone or muscle may be destroyed. Dry, Leathery appearance with swelling.
Term
Cardiovascular Burn Response
Definition
Fluid and protein move out of the vascular compartment
Results:
Decreased cardiac output
elevated hematocrit
elevated WBCs
hypoproteinemia
Term
Cellular burn response
Definition
impairment of Na-K pumps
Results:
cellular swelling w/ decreased potassium and disruption of transmembrane potential
Term
ABCD rule
Definition
Asymmetry
Border irregularity
Color variation
Diameter > 6mm
Term
Kaposi sarcoma
Definition
vascular malignancy assoc. w/HIV and AIDS
Purplish-brown macules--> dev into plaques and nodules
pruritic and painful
75% involvement of lymph nodes of GI tract and lungs
Term
Basal Cell Carcinoma
Origination:
Characteristics:
Definition
O: Interfollicular basal cells, Hair follicles, and sebaceous glands.
C: depressed centers and rolled borders
Do not metastasize beyond skin, grow by direct extension
Term
Basal Cell Carcinoma
Origination:
Characteristics:
Definition
O: Interfollicular basal cells, Hair follicles, and sebaceous glands.
C: depressed centers and rolled borders
Do not metastasize beyond skin, grow by direct extension
Term
Squamous Cell Carcinoma: Clinical
Definition
confined to epidermis
C: red, scaling, keratotic, slightly elevated lesion; irregular border; chronic crusty ulcerations; raised erythematous borders
Term
Malignant Melanoma
Definition
rapidly progressing malignant tumor of the melanocytes. Metastasis occurs through lymph nodes.
Term
Seborrheic keratosis
Definition
O: Benign proliferation of basal cells
C: smooth or wary in appearance; tan to waxy yellow, flesh-colored, dark-brown; oval and greasy.
Term
Keratoacanthoma
Origination
Characteristics
Definition
O: arises from hair follicles
C: dome-shaped, crusty lesions filled with keratin.
Term
Actinic keratosis
Origination
Characteristics
Definition
CAN TURN MALIGNANT
O: skin surface
C: pigmented patch of rough, adherent scale
Term
Nevi
Origination
Characteristics
Definition
CAN TURN MALIGNANT
O: skin
C: pigmented or non-pigmented lesions that form from melanocytes beginnning at age 3-5.
Term
Urticaria
Characteristics
origination
Definition
C: whaels, hives, welts
O: hypersensitivity reactions to drugs, systemic diseases, or physical agents
Term
Scleroderma: Systemic
Origination
Characteristics
Definition
O: sclerosis of the visceral organs(kidneys, GI Tract, lungs)
C: hard, hypopigmented, taut, shiny, and tautly connected to underlying tissue.
Term
Scleroderma: Cutaneous
Origination
Characteristics
Definition
O: face hands, neck, and upper chest
C: hard, hypopigmented, tut, shiny, and tightly connected to underlying tissue.
Term
Folliculitis
Definition
bacterial infection of the hair follicle
Term
Furuncles
Definition
Infection of the hair follicle that extends to the surrounding tissue
Term
Carbuncles
Definition
collection of infected hair follicles that forms a draining abscess
Term
Cellulitis
Definition
diffuse infection of the dermis and sucutaneous tisssue
Term
Erysipelas
Definition
Superficial streptococcal infection of the skin (face, ears, and lower legs)
Term
Impetigo
Definition
bullous or ulcerative lesion caused by Staphylococcus or streptococcus
Term
Herpes Simplex Virus: HSV1
Definition
causes cold sores; can affect cornea, mouth, labia
Term
Herpes Simplex Virus: HSV2
Definition
genital lesions; usually spread by sexual contact
Term
Erythema multiforne: types
Definition
acute inflammation of skin and mucous membranes with lesions. Stevens-Johnson syndrome-common w/antibiotics can be fatal
Toxic epidermal necrolysis-skin sloughs off
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