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Pathophysiology
Cell Biology
60
Nursing
Undergraduate 3
09/04/2015

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Cards

Term
What do cells do?
Definition

1. Movement

2. Conductivity

3. Metabolic absorption

4. Secretion

5. Excretion

6. Respiration

7. Reproduction

8. Communication

Term
Cells multiply by what process?
Definition
Mitosis
Term
Nucleus
Definition

control center of cell

 

where genetic information from DNA is transcribed to RNA

 

surrounded by nuclear membrane (allows passage of substances)

 

Term
Nucleolus
Definition
Assembles ribosomes which make proteins
Term
Cytoplasm
Definition

Mostly water containing chemical compounds and structures (minerals, gases, organic molecules, cell organelles)

 

Many chemical reactions take place here

Term
Plasma (cell) membrane
Definition

critical component of cell

 

essential for communication and function

 

double phospholipid layer which is impermeable except to lipid-soluable substances, unless helped by other molecules or processes

Term
Ribosomes
Definition

Protein factories

 

build proteins out of amino acids/protein synthesis

Term
Lysosomes
Definition

housekeeper

 

contain enzymes that break down cells and substances

 

digestive bags-digest unwanted substances in cell with enzymes

Term
Peroxisomes
Definition
breakdown toxic products in cell
Term
mitochondria
Definition

power house of cell

 

makes energy/cell respiration -> ATP

 

involved in controlling cell growth and death

Term
Mitochondria have their own DNA that comes from...
Definition

the mother

 

can trace maternal lineage through mitochondrial DNA

Term
Golgi apparatus
Definition

storage warehouse/ post office

 

can synthesize large carbohydrates

 

sorts and packages proteins, like insulin, for secretion

Term
Endoplasmic reticulum
Definition

system of channels for transport

 

rough: for protein synthesis from attached ribosomes

 

smooth: for fat transport and sex hormone synthesis

Term
Cytoskeleton
Definition

controls cell shape, movement, and internal organization

 

permit movement of substances in a cell

 

microtubules (cilia, flagella, centrioles)

 

microfilaments (support, anchor, contractile ability)

 

Term
cilia
Definition
move substances
Term
flagella
Definition
move cells
Term
Centrioles
Definition

form spindle fibers during cell division

 

guide duplicated chromosomes to daughter cells

Term
Alzheimer's markers
Definition
Neurofibrillary tangles and amyloid plaques
Term
Cell communication
Definition

needed to maintain homeostasis

 

signal through hormones, neurotransmitters, and other chemical messengers that bind with specific cell receptors

 

 

Term
Cell receptors
Definition

proteins that bind with specific substances, like hormones

 

variety of receptors on surface of plasma membranes and inside

 

trigger reactions

 

allow substances into cells

Term
cell-to-cell adhesion
Definition

allow groups of cells to stick together

 

involves extracellular matrix - complex structure of collagen and other proteins like structure in between cells to form tissue

 

matrix is secreted by fibroblasts which are essential for healing

 

decreased adhesion occurs in cancer and leads to metastasis (cells break off and travel)

Term
specialized cell junctions
Definition
permit molecules to pass from cell to cell
Term
cellular metabolism
Definition

take O2 and nutrients from food (protein, carbs, fats) to make energy

 

anabolism: requires energy-building up

catabolism: releases energy-breaking down

Term
anaerobic metabolism
Definition

doesn't require oxygen

 

needed for cells that don't have mitochondria

 

doesn't supply most of our energy needs, but may provide a boost

Term
aerobic metabolism
Definition

utilizes oxygen

 

supplies 90% of body's energy needs

 

occurs in mitochondria

Term
energy in the form of ATP is produced by...
Definition
glycolysis, citric acid cycle, and oxidation
Term
glycolysis
Definition

making ATP for energy from glucose

 

anaerobic

 

not a lot of energy produced but produces other neccessary molecules

 

neccessary sometimes even if O2 is available

Term
citric acid cycle (Krebs)
Definition

aerobic

 

utilizes nutrients

 

 

Term
oxidation (electron transport chain)
Definition

aerobic

 

combines O2 and H+ to get H2O and ATP

Term
waste products from ATP production
Definition

urea

NH3

water

CO2

Term
membrane transport
Definition
movement of water and solutes across semipermeable into or out of cells
Term
types of passive transport
Definition

diffusion

 

facilitated diffusion

 

osmosis

Term
diffusion
Definition

easiest type of transport

 

higher to lower solute concentration

 

down a concentration gradient

 

 

Term
facilitated diffusion
Definition

also down concentration gradient

 

for moleclues that are too big or arent lipid soluble

 

facilitated by carrier protein

 

 

Term
osmosis
Definition

movement of water from higher to lower concentration

 

solutes in fluids act like water magnets

Term
hypertonic solution
Definition
more solute outside so water flows out of cells
Term
isotonic solution
Definition
same concentration outside the cell as inside
Term
hypotonic
Definition
less solute outside cell, water fows into cell and swells or bursts
Term
active transport
Definition

requires energy

 

lower to higher concentration

 

needed for muscle conraction and nerve impulses

 

NA+/K+ pump

Term
filtration
Definition
highr pressure to lower pressure
Term
phagocytosis
Definition
cell eating
Term
pinocytosis
Definition
smaller substances taken in
Term
Tissue
Definition

groups of cells with similar structure and function

 

occurs after concenption when fertilized egg undergoes divisions and changes into different types of cells through cell differentiation

Term
Basic types of tissue
Definition

epithelial

connective

nerve

muscle

Term
epithelial tissue
Definition

basement membrane-anchor

 

line surfaces and structures/form glands

 

named according to shape, arrangement, function

 

cells are closely packed

 

usually high rate of turnover

 

 

Term
simple epithelial
Definition

single layer linig or covering a structure

 

endothelium: lines vessels

mesothelium: lines cavities

Term
stratified epithelial
Definition

more than one layer

 

barrier to pathogens

 

bottom layer undergoes mitosis before top layer

 

mucous membranes, ducts of glands, respiritory passages, bladder

 

transitional stratified can change shapes/stretch

Term
glandular epithelial
Definition

specialized to produce secretions

 

Term
glands
Definition

organs or cells that secrete something

 

can be unicellular (goblet cells that produce mucous)

or multicellular

Term
endocrine
Definition

ductless

 

pituitary, thyroid, adrenal

Term
exocrine
Definition

have ducts

 

sweat, mammary, GI tract

Term
connective tissue
Definition

binds and supports tissues and organs and serves as storage site for excess nutrients

 

most abundant tissue in body

Term
areolar/loose connective tissue
Definition
most abundant tissue are fibroblasts
Term
fibroblasts
Definition
make filler substances like collagen, elastin
Term
adipose tissue
Definition

store triglycerides

 

fill spaces, keep organs in place

 

good insulator

 

white fat/brown fat-each metabolized differently

Term
specialized connective tissue
Definition

bone

blood

cartilage

Term
muscle tissue
Definition

smooth, striated, and cardiac

 

Term
smooth (visceral)
Definition

involuntary

 

digestive tract, arteries and veins, ureters

Term
striated (skeletal)
Definition

voluntary

 

movement

 

one of the most abundant tissues in body

 

 

Term
cardiac muscle
Definition

has featured of striated and smooth

 

involuntary

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