Term
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Definition
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Term
| endocrine deficiency syndrome that has partial or complete loss of anterior lobe pituitary function is called _________ |
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Definition
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Term
| tx and Dx for Hypopituitarism |
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Definition
Diagnosis: imaging tests, measurement of pituitary hormone levels
(basally & via various provocative stimuli) Unusual sensitivity to insulin
Fasting hypoglycemia
GH level
Levels of other pituitary hormones
Treatment: depends on cause
tumor removal
administration of replacement hormone |
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Term
| Etiology of hypopituitarism : 4 of them |
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Definition
Pituitary tumors
Vascular thrombosis leading to necrosis
Idiopathic or autoimmune disease
Less common causes – sarcoidosis, syphilis, tuberculosis, hemochromatosis & fungal infection |
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Term
| which hormone is lost first in hypopituitarism? |
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Definition
Growth hormone (GH) is usually lost first, then gonadotropins, and finally thyroid-stimulating hormone (TSH) and ACTH.
ADH deficiency is rare in primary pituitary disease but is common with stalk and hypothalamic lesions.
Function of all target glands decreases when all hormones are deficient (panhypopituitarism). |
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Term
what is this condition?
Children leads to delayed puberty
Premenopausal women: amenorrhea, decrease libido, regression of secondary sexual characteristics, and infertility.
Men: erectile dysfunction, testicular atrophy, decrease libido, regression of secondary sexual characteristics, and decreased spermatogenesis --> infertility |
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Definition
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Term
name this condition
pituitary dwarfism, poor sexual development, adrenal insufficiency, hypothyroidism and pale skin. |
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Definition
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Term
| _________ deficiency may contribute to decreased energy but is usually asymptomatic and clinically undetectable in adults. |
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Definition
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Term
| ______________ condition comes with such symptoms as facial puffiness, hoarse voice, bradycardia, and cold intolerance, lazy feelings, obesity, loss of energy |
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Definition
| TSH deficiency: hypothyroidism |
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Term
| what hormone deficiency would cause : hypoadrenalism with fatigue, hypotension, and intolerance to stress and infection? |
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Definition
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Term
| lesion in what part of the brain could result in hypopituitarism, can also disturb the centers that control appetite, producing a syndrome resembling anorexia nervosa, or sometimes hyperphagia with massive obesity |
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Definition
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Term
name syndrome that Affects postpartum women
Pituitary necrosis from hypovolemia and shock occurring in the immediate peripartum period.
S&S: lactation does not start after childbirth, fatigue , loss of pubic and axillary hair. |
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Definition
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Term
what condition is caused by hemorrhagic infarction of pituitary gland?
symptoms may include severe HA, stiff neck,fever, visual field defects, oculomotor palsies. pt may go in to somnolence or coma. |
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Definition
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Term
| Pituitary apoplexy could cause what to vascular system and CSF? |
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Definition
May present with vascular collapse because of deficient ACTH and cortisol.
The CSF often contains blood, and MRI documents hemorrhage. |
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Term
swelling of soft tissue, peripheral nerves are englarged
delayed puberty and hypogonadism is freq
it begins in childhood before closure of epiphyses. common you can answer this..what is it |
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Definition
| Pituitary giantism. GH hypersecretion |
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Term
this condition of excessive excessive secretion of growth hormone that are nearly always due to a pituitary adenoma happens after epiphyses is closed.(so not in childhood)
it produce distinctive facial and other features |
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Definition
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Term
| Many growth hormone (GH) secreting adenomas contain a mutant form of the ____ protein. |
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Definition
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Term
| acromegaly starts between what age? |
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Definition
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Term
| what bone is often distinctively enlarged in acromegaly? |
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Definition
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Term
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Definition
Peripheral neuropathies
HA, HTN, increase risk of cancer
bitemporal hemianopia
main organs including thyroid, spleen, pancrease are larger than normal |
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Term
| excess of _____ alone is enough to stimulate lactation (galactorrhea) |
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Definition
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Term
| there are like 15 slides on acromegaly ..so read that from PPT |
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Definition
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Term
| three main types of pituitary tumors are.. |
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Definition
Pituitary Adenomas
Craniopharyngiomas
Meningiomas |
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Term
| clinical features of pituitary tumors |
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Definition
excess hormone
insufficient hormone
neurological effects
microademonas
type 1 wermer syndrome |
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Term
| what happens in cushing syndrome? |
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Definition
caused by hypercortisolism which can increase ATCH due to pituitary adenoma/hyperplasia.
it causes moon facies, buffalo hump, hyperglycemia, osteoporosis, muscle wasting weakness, purple striae |
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Term
| what are two Disorders of Antidiuretic Hormone ? |
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Definition
Central diabetes insipidis – deficiency of ADH due to a hypothalamic-pituitary disorder
Syndrome of inappropriate secretion of ADH (SIADH) – increased secretion of ADH |
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Term
| clinical features of DI : 3 P's |
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Definition
| polyuria, polyphagia & polydipsia |
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Term
| two types of DI and its etiology |
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Definition
central and nephrogenic.
Etiology: 50% idiopathic, could be due to injury to the hypothalmus-pituitary area & encephalitis. |
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Term
diagnosis of DI
managment of DI : 3 drugs |
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Definition
Diagnosis:
Measurement of plasma osmolarity
Water deprivation test
drugs
Desmopressin (dDAVP)
Chlorpropamid.
Thiazide diuretics. |
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Term
| ADH levels and response to exogenous ADH help distinguish ___________ |
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Definition
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| The only symptoms in primary CDI are ___________ and ___________ |
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Definition
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Term
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Definition
| Patients with CDI are generally unable to concentrate urine to greater than the plasma osmolality but are able to increase their urine osmolality by > 50% after vasopressin administration. |
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Term
| water deprivation test for NDI |
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Definition
| Patients with NDI are unable to concentrate urine to greater than the plasma osmolality and show no additional response to vasopressin |
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Term
| SIADH's most common caused by .. |
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Definition
ectopic ADH production by small cell bronchogenic carcinoma and other tumor.
other causes: stroke, head injury, encephalitis and pharmacologic agents |
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Term
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Definition
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Term
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Definition
| nausea, Retching, and Vomiting (what the hell?) |
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Term
| two most common type of gastritis |
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Definition
acute superficial gastritis
chronic atrophic gastritis |
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Term
| 4 things could cause A. superficial Gastritis |
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Definition
H.Pylori
NASIDs
Caffeine
Alcohol |
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Term
| Chronic atrophic gastritis is characterized by: |
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Definition
Chronic atrophic gastritis is characterized by:
Progressive atrophy of the glandular epithelium
Loss of parietal and chief cells
Hypochlorhydria or achlorhydria |
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Term
| what happens in zollinger ellison syndrome? you should know this its very uncommon...lol |
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Definition
an uncommon cause of peptic ulcers.
Caused by a gastrin-secreting neoplasm (gastrinoma)
Resulting in extreme gastric hyperacidity |
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