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Pathophysiology Bacteria
60 Medically Important Bacteria
60
Medical
Graduate
11/09/2015

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Term
Bacillus anthracis
Definition
Gram Positive Rods Facultative Anaerobe Causes: Anthrax Forms spores. Often found in animals (carcasses) and in the dirt.
Term
Brucella species
Definition

Gram Negative Coccobacilli

Facultative Intracellular

Causes: Brucellosis (a zoonosis)

Flagelated. Transmitted to humans by contact with infected animal.

Diagnosis: Serology or Culture
Term
Borrelia burgdorferi
Definition
Diderm Anaerobic Causes: Lyme Disease (Bulls Eye Rash) Spirochete. Spread by ticks. High virulence.
Term
Bordatella pertussis
Definition
Gram Negative Coccobacillus (Short Rods) Aerobic Causes: Pertussis (Whooping Cough) Spread by airborne droplets. Humans are the only host. Effective by Pertussis Toxin? Diagnose: PCR. serology. Culture.
Term
Bacteroides fragilis
Definition
Gram Negative Rods Obligate Anaerobe Causes: Peritoneal infections, bacteremia, abscesses. Normal Flora: Colon, Throat, Vagina. Usually commensal, but infectious if displaced into bloodstream (surgery, trauma). Below diaphragm.
Term
Bartonella Species
Definition
Gram Negative Facultative Intracellular Parasite? Causes: Cat Scratch disease (B. henselae [rod]) Can infect healthy people, but also opportunistic. Transmitted by vectors (ticks, fleas, mosquitos)
Term
Campylobacter Species
Definition

Gram Negative Spirals.

Microaerophilic

Causes: Bloody diarrhea. In the colon. Treat with antibiotics.

Term
Chlamydophila pneumoniae
Definition

Gram Negative 

Obligate Intracellular

Found: 

Major cause of pneumonia

Term
Chlamydia trachomatis
Definition
Gram Negative Ovoid Obligate Intracellular Causes: Trachoma (eye infection), urethritis, pelvic inflammatory disease, ectopic pregnancy, neonatal pneumonia, conjunctiva, LGV (lymph infection: buboes around groin, neck, or anus) Look for inclusion bodies on gram stain!
Term
Clostridium botulinum
Definition
Gram Positive Rod Anaerobic Causes: Botulism Produces Botulinum Toxin (Neurotoxin) Normal Flora (Colon).
Term
Clostridium difficile
Definition
Gram Positive Rods Anaerobe Causes: Pseudomembranous colitis, C. Diff diarrhea Found in water, feces, soil, most surfaces, etc. Normal Flora: Colon
Term
Clostridium tetani
Definition
Gram Positive Rods Obligate anaerobe Causes: Tetanus Creates spores. Found in soil, dust, sediment. Normal Flora: Colon
Term
Corynebacterium diphtheriae
Definition
Gram Positive Rods Aerobic Causes: Diphtheria Produces Diphtheria toxin (inhibits protein synthesis) ....
Term
Coxiella burnetti
Definition
Gram Negative Coccobacillus Obligate Intracellular Causes: Q Fever Found in sheep/cattle/goat waste
Term
Ehrlichia chaffeensis
Definition
Gram Negative Cocci Obligate Intracellular Causes: Ehrlichiosis (Fever, headache, fatigue, muscle aches. Treat with Doxy) Zoonotic. Tick borne illness.
Term
Eikenella species
Definition
Gram Negative Facultative Anaerobe Causes: Eikenella infection (periodontitis, osteomyelitis, etc) Normal Flora: Mouth.
Term
Enterobacter Species
Definition
Gram Negative Rods Facultative Anaerobic Causes: Pneumonia, Urinary Tract Infection Opportunistic and often nosocomial. Sometimes drug resistant.
Term
Enterococcus Species
Definition

Gram Positive Cocci Facultative Anaerobes

Normal Flora: Colon.
Term
Escherichia Coli
Definition
Gram Negative Rods. Facultative anaerobe. Culture: Lactose-fermenting, beta-hemolytic Produces Shiga toxin Causes: UTI, Traveler's Diarrhea, Neonatal Meningitis Normal Flora: Colon, vagina,
Term
Francisella tularensis
Definition
Gram Negative coccobacillus (Zoonosis) Aerobic Causes: Tularemia Source: Rabbits, Deer, Ticks (Contact or Tick Bite) Diagnosis: Serology
Term
Gardnerella vaginalis
Definition
Gram Variable Facultative Anaerobe Causes: Bacterial Vaginosis (disruption of Normal Flora) Selective Media: Colistin-oxolinic acid blood agar (Grows on Chocolate agar and HBT agar) Normal Flora: Vagina
Term
Haemophilus ducreyi
Definition
Gram Negative coccobacillus Causes: Chancroid (STI causing painful genital ulcers, green feces) Generally opportunistic. Cultured on chocolate agar.
Term
Haemophilus influenzae
Definition
Gram Negative Coccobacillus Facultative Anaerobe. Causes: bacteremia, pneumonia, epiglottitis, acute bacterial meningitis, Otitis Media. Opportunistic Pathogen! Normal Flora: Throat. Diagnose: Culture. capsular polysaccharide in serum or spinal fluid.
Term
Helicobacter Pylori
Definition
Gram Negative Helix microaerophilic Causes: Gastritis, Peptic ulcer Stained with: Gram, Giemsa, haematoxilyn-eosin, WS Silver, Orange, and Phase-contrast Found in the stomach?
Term
Klebsiella pneumonia
Definition
Gram negative rods Facultative anaerobe Normal Flora: Mouth, Skin, Intestines Causes: Primary Pneumonia, UTI Stain: Gram Stain (Made for K. pneumonia)
Term
Lactobacillus Species
Definition

Gram Positive Bacilli Facultative Anaerobes or Microaerophilics Normal Flora: Mouth, Colon, Vagina

Opportunistic. Causes: Dental carries, infections?

Term
Legionella pneumophila
Definition
Gram Negative pleomorphic Aerobic Causes: Legionnaires Disease (Pneumonia Subtype) Stain: Prolonged Stain time!
Term
Listeria monocytogenes
Definition
Gram Positive Rods No anaerobic growth, no spore, no exotoxins. Food Borne! Causes: Meningitis, Sepsis Stain: Gram Neonate/Immunosuppression predisposing factors.
Term
Moraxella catarrhalis
Definition
Gram Negative Diplococcus Aerobe Causes: Meningitis, Otitis media, sinusitis Diagnose: Culture
Term
Morganella
Definition
Gram Negative Rod Stain: Blood or McConkey Usually nosocomial/opportunistic Causes: UTI (outside tract)
Term
Mycobacterium Atypicals
Definition
M. kansasii: TB-like syndrome M. marinum: Swimming pool granuloma M. avium-intracellulare complex: TB-like syndrome in immunocompromised
Term
Mycobacterium tuberculosis
Definition
Requires acid-fast stain
Term
Mycobacterium pneumoniae
Definition
No cell wall. Classified as parasite. Causes: Mycoplasma Pneumonia (atypical pneumonia related to cold-agglutinin disease),
Term
Neisseria gonorrhoeae
Definition

Gram Negative Coccus (Usually in pairs) Facultative intracellular Causes: Gonorrhea (dysuria, discharge, pain)

Normal Flora: Mouth, Nasopharynx. Culture: Fastidious (Require chocolate agar with CO2 Urine tests/sample. Gram stain.

Term
Neisseria meningitidis
Definition
Gram Negative Coccos Causes: Meningitis (fever, headache, neck stiffness, coma), meningococcal disease (septicemia) Diagnosis: Chocolate Agar/Thayer-Martin Agar, Exclusively human. Normal Flora: Mouth, Nasopharynx. Medical emergency.
Term
Nocardia
Definition
Gram Positive Bacillus Catalase positive, Cause: Nocardiosis (lung/systemic infection, weakened immune system) Stain: Ziehl-Neelson stain, weakly acid-fast. Found in soil.
Term
Pasteurella multocida
Definition
Gram Negative Coccobacillus Causes: Infection from cat/dog bites, bacteremia, and meningitis. Rapidly spreading cellulitis. Look for lymphangitis. Penicillin-sensitive. Found in animals and humans. Diagnosis: Wound Culture.
Term
Prevotella melaninogenica
Definition
Gram Negative Coccobacilli Obligate Anaerobic, Opportunistic Normal Flora: Dental. Found in the rumen of cattle/sheep. Cause: Deep tissue infections! Sepsis. Opportunistic infections (oral abscesses, gut infections, respiratory infections, female genitalia infections.
Term
Proteus
Definition
Gram Negative Bacillus Found in decomposing animal matter, sewage, human/animal waste, manure soil. Opportunistic pathogens often causing sepsis and urinary tract infections. Often nosocomial. Culture: MacConkey agar. Includes: P. vulgaris, P. penneri, P. mirabilis
Term
Providencia
Definition
Gram Negative Opportunistic. Cause: Urinary tract infections (particularly in patients with long-term catheters or severe burns).
Term
Pseudomonas aeruginosa
Definition
Gram negative bacillus Aerobic Opportunistic. Often cross-infection causing (on hospital supplies), Implicated in hot tub rash. Can cause fatal results in organs. Otitis media. Found: Soil, water, skin flora, man-made environments.
Term
Rickettsia
Definition
Gram Negative Pleomorphic (cocci, rods, stringlike) Obligate Intracellular Parasite Carried by arthropods (chiggers, ticks, lice, etc) Causes: Typhoid fever, Rickettsialpox, Boutonneuse fever, African tick bite fever, Rocky mountain spotted fever, Flinders Island spotted fever, Queensland tick typhus.
Term
Serratia marcescens
Definition
Gram Negative Bacillus Found: Dirt, "Sterile" places, subgingival biofilm of teeth. Causes: (Opportunistic) Hospital Acquired Infections: catheter-associated bacteremia, UTI, pneumonia. (Respiratory/UTI in adults, GI in kids)
Term
Shigella dysenteriae
Definition
Gram Negative Bacillus Facultative anaerobe Found: Contaminated food/water (fecal-oral) Causes: Shigellosis (bacterial dysentary) Cultured: Selective Plates (XLD agar, DCA agar, Hektoen enteric agar. Toxin: Shiga Toxin
Term
Staphylococcus Aureus
Definition
Gram Positive Cocci Facultative Anaerobe Found: Normal Flora (Skin, nostril) Causes: Infections from skin (impetigo, cellulitis) to organ systems (pneumonia, meningitis, sepsis)
Term
Staphylococcus epidermidis
Definition
Gram Positive Cocci Facultative anaerobe Found: Normal Flora (Skin, Nostril) Causes: Hospital-Acquired/Opportunistic infections
Term
Streptococcus agalactiae
Definition
Gram Positive Cocci Facultative Anaerobe Found: Normal Flora (GI, GU tract) Culture: Beta-hemolysis on Blood Agar plates
Term
Streptococcus pneumoniae
Definition
Gram Positive Cocci Facultative Anaerobe Found: Normal Flora (Nasopharynx) Causes: PNEUMONIA, 2nd most common in Otitis media, meningitis. Mostly opportunistic!
Term
Streptococcus pyogenes
Definition
Gram Positive Cocci Found: Normal Flora (Throat) Causes: scarlet fever, Impetigo, pharyngitis, sepsis, toxic shock Culture: Group A hemolysis on blood agar
Term
Group D Strep
Definition
Bovis: Gram Positive Cocci. Found: Normal Flora (Colon). Cause: Endocarditis. Alpha/Gamma hemolysis.
Equinus:
Term
Treponema Pallidum
Definition
Gram Negative spirochete Found: Diagnose: Dark Field Illumination Cause: Syphilis, bejel, pinta, yaws??
Term
Vibrio Species
Definition
Gram Negative Curve-shaped Facultative Anaerobe Found: Contaminated water or undercooked seafood Causes: Watery diarrhea! Gastroenteritis, septicemia, cholera, etc. Small intestine. Treat with fluid.
Term
Yersinia enterocolitica
Definition
Gram Negative Bacillus Found: Nature (Intestines of mammals, avians, cold-blooded species, and terrestrial/aquatic niches. Causes: Enterocolitis, acute diarrhea, terminal ileitis, mesenteric lymphadenitis, pseudoappendicitis, fatal sepsis.
Term
Yersinia pestis
Definition
Gram Negative Bacillus Facultative anaerobe Found: Rodents Causes: Bubonic plague, septicemic plague, pneumonic plague Visualize: PCR Identified: Immunoflourescence or culture.
Term
Burkholderia cepacia
Definition
Gram Negative Causes: Pneumonia (in immunocompromised with underlying lung disease [CF or chronic granulomatous disease])
Term
Proprioibacterium acnes
Definition
Gram Positive Bacillus Anaerobe Causes: Acne, chronic blepharitis, endophthalmitis Found: Normal Flora (Skin)
Term
Salmonella enteritidis
Definition
Term
Salmonella Typhi
Definition
Systemic. Patient usually constipated.
Term
Salmonella typhimurium
Definition
Gram Negative Bacillus
Aerobic
Term
Streptococcus veridans
Definition
Gram Positive
Normal Flora: Mouth
Alpha hemolysis
Cause: Endocarditis
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