Term
|
Definition
| stratum basalis, spinosum, granulosum, corneum |
|
|
Term
|
Definition
| eczema; pruritic oozing rash with vesicles and edema; type I HSR |
|
|
Term
| with asthma and allergic rhinitis |
|
Definition
|
|
Term
| causes of contact dermatitis |
|
Definition
| poison ivy and nicely jewelry, irritant chemicals, drugs |
|
|
Term
| treatment of acne vulgaris |
|
Definition
| benzoyl peroxide and vitamin A derivatives (isotretinoin) |
|
|
Term
| salmon colored plaques with silvery scale |
|
Definition
|
|
Term
| excessive keratinocyte proliferation |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| acanthosis, parakeratosis, munro microabscesses |
|
|
Term
|
Definition
|
|
Term
|
Definition
| hyperkeratosis with retention of keratinocyte nuclei in stratum corneum |
|
|
Term
|
Definition
| collection of Nt in stratum corneum |
|
|
Term
|
Definition
| thinning of epidermis above elongated dermal papillae -> bleeding |
|
|
Term
| pruritic, planar, polygonal, purple papules |
|
Definition
|
|
Term
|
Definition
|
|
Term
| saw tough dermal-epidermal junction |
|
Definition
|
|
Term
| with chronic HCV infection |
|
Definition
|
|
Term
| pemphigous vulgaris mechanism |
|
Definition
| IgG agaisnt desmoglein (type II HSR) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| bullous pemphigoid mechanism |
|
Definition
| autoimmune destruction of hemidesmosomes between basal cells and underlying basement membrane |
|
|
Term
|
Definition
|
|
Term
| deposition of IgA in the dermal papillae |
|
Definition
|
|
Term
|
Definition
|
|
Term
| targetoid rash and bullae |
|
Definition
|
|
Term
| causes of erythema multiforme |
|
Definition
| HSV, mycoplasma, drugs (penicillin and sulfonamides), SLE and malignancy |
|
|
Term
| SJS vs toxic epidermal necrolysis |
|
Definition
SJS= erythema multiform with oral involvement and fever
TEN= diffuse sloughing of skin, resembling large burn |
|
|
Term
|
Definition
|
|
Term
|
Definition
| sudden onset of multiple seborrheic keratoses and suggests underlying carcinoma of GI tract |
|
|
Term
| velvet like skin of axilla or groin |
|
Definition
|
|
Term
| associated with insulin resistance or malignancy |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| peripheral palisading cells |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| precursor of SCC with hyperkeratotic scaly plaque |
|
|
Term
|
Definition
| SCC that develops rapidly and regress spontaneously |
|
|
Term
| mechanism of skin pigmentation |
|
Definition
| melanocytes synthesize melanin in melanosomes and pass them to keratinocytes |
|
|
Term
|
Definition
| localized loss of skin pigmentation; AI destruction |
|
|
Term
|
Definition
|
|
Term
|
Definition
| freckle, small tan to brown macule; inc number of melanosomes |
|
|
Term
|
Definition
| hyper pigmentation of cheeks; pregnancy and oral contraceptive |
|
|
Term
|
Definition
| begins as nests of melanoctes at dermal epidermal junction -> grows by extension into dermis (compound) -> junctional component lost = intradermal nevus |
|
|
Term
| risk factors for melanoma |
|
Definition
| UVB, albnism, xeroderma pigmentosum, dysplastic nevus syndrome |
|
|
Term
| two growth types of melanoma |
|
Definition
radial= horizontally
vertical= depth is breslow thickness most important prognostic factor |
|
|
Term
| superficial spreading melanoma |
|
Definition
| most common; dominant early radial growth results in good prognosis |
|
|
Term
|
Definition
| lentigious proliferation (radial growth), good prognosis |
|
|
Term
|
Definition
| early vertical growth; poor prognosis |
|
|
Term
| acral lentiginous melanoma |
|
Definition
| on palms or soles; in dark-skinned individuals, not related to UV |
|
|
Term
|
Definition
|
|
Term
| rupture of pustule results in erosions and dry crusted honey colored serum |
|
Definition
|
|
Term
| red tnder slowwen rash with fever |
|
Definition
|
|
Term
|
Definition
| necrosis of subcutaneous tissues due to infection with anaerobic 'flesh eating' bacteria |
|
|
Term
|
Definition
| S aureus; sloughing of skin with erythematous rash and fever |
|
|
Term
| exfoliative A and B toxins |
|
Definition
| epidermolysis of the stratum granulosum |
|
|
Term
|
Definition
TEN = dermal epidermal junction
SSS= stratum granulosum |
|
|
Term
|
Definition
|
|
Term
| firm, pink, umbilicated papules |
|
Definition
|
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