Term
| general incidence of primary carcinoma of the vagina |
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Definition
| extremely rare, often involved secondarily by cancer or infections arising in adjacent organs |
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Term
|
Definition
| Adenosis is the presence of glandular epithelium in the vaginal wall (which is normally lined by nonkeratinizing stratified squamous epithelium). |
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Term
| putative causative agent of adenosis |
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Definition
| developmental abnormality observed in female children who were exposed to diethylstilbestrol (DES) in-utero. |
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|
Term
| and explain the relationship of adenosis to carcinoma of the vagina |
|
Definition
| metaplasia, can lead to clear cell carcinoma |
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|
Term
| incidence of clear cell carcinoma of the vagina |
|
Definition
| very rare tumor (except upon exposure to DES) |
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|
Term
| clinical course of clear cell carcinoma of the vagina |
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Definition
| : exposure leads to small glandular or microcystic inclusions that appear on vaginal mucosa. Red granular-appearing foci lined by mucus secreting cells = adenosis --> clear cell carcinoma |
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|
Term
| incidence of squamous carcinoma of the vagina |
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Definition
| extremely rare, 60 years old +, |
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|
Term
| clinical symptoms of squamous carcinoma of the vagina |
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Definition
| Usually well-differentiated, associated with HPV infection |
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|
Term
| most common anatomic sites involved in squamous carcinoma of the vagina |
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Definition
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|
Term
| incidence of sarcoma botryoides |
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Definition
| embryonal rhabdomyosarcoma of the vagina of infants and children under age 5. |
|
|
Term
| gross features of sarcoma botryoides |
|
Definition
| the tumor protrudes like a bunch of grapes from the vagina |
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|
Term
| clinical course of sarcoma botryoides |
|
Definition
| can also occur in urinary bladder or bile ducts |
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