Term
| Sialadenitis (definition) |
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Definition
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Term
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Definition
| viral (mumps), bacterial, or autoimmune origin (Sjögren syndrome). |
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Term
| pathogenesis of Sialadenitis |
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Definition
| obstruction of excretory duct by stone which may result in secondary bacterial infection |
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Term
| Clinical significance of Sialadenitis |
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Definition
| bacterial infections are common |
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Term
| incidence of pleomorphic adenoma |
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Definition
| : 75 % of tumors of major salivary glands |
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Term
| clinical features of pleomorphic adenoma |
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Definition
| Contain epithelial elements in a background of gelatinous, mucoid, myxoid, and/or chondroid tissue. |
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Term
| course of disease of pleomorphic adenoma |
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Definition
| 90% are benign, but most are slow growing and well demarcated and located in superficial parotid, excision is difficult due to involvement of facial nerve, 10% recur after surgery |
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Term
| incidence of adenolymphoma |
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Definition
| 5-10% of salivary tumors (parotid gland) |
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Term
| clinical features of adenolymphoma |
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Definition
| : Consists of cyst or cleft-like spaces lined by tall columnar cells with granular, very eosinophilic (pink) cytoplasm, associated with abundant lymphoid tissue |
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Term
| course of disease of adenolymphoma |
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Definition
| Slow growing, benign tumor cured by excision |
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Term
| incidence of mucoepidermoid tumor |
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Definition
| 5-10% of salivary tumors, most often in the parotid glands |
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Term
| clinical features of mucoepidermoid tumor |
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Definition
| Composed of mixtures of squamous cells, mucus-secreting cells, and intermediate cells |
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Term
| course of disease of mucoepidermoid tumor |
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Definition
| Tumors range from benign to overtly malignant, biologic behavior may be difficult to predict from histology. Overtly malignant tumors metastasize to regional nodes and distant sites. Five year survival for well-differentiated tumors - 90%; poorly differentiated- 20-30% |
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Term
| incidence of adenoid cystic carcinoma |
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Definition
| uncommon, low-grade tumor of major salivary glands occurs more often in minor salivary glands |
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Term
| clinical features of adenoid cystic carcinoma |
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Definition
| : Composed of small dark cells with scant cytoplasm, forming cystic spaces that contain PAS-positive, mucinous or eosinophilic hyalinized material. |
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Term
| course of disease of adenoid cystic carcinoma |
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Definition
| as malignant tumors, tend to involve nerve, spread through the bloodstream and metastasize to distant sites. Five year survival rate is 60 to 70%; ten year survival drops to 30%; 15 year survival rate - 15%. |
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