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Pathology Unit II
Infarction
16
Pathology
Graduate
01/27/2013

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Term
Infarct
Definition
a localized area of ischemic necrosis in an organ or tissue resulting from sudden reduction of either its arterial supply or venous drainage
Term
General morphology of infarcted organs
Definition
classified on basis of color (reflecting amount of hemorrhage) and the presence or absence of microbial infection: Red or White, Septic or Bland
Term
Red Infarcts
Definition
occur with venous occlusions, loose tissues, tissues with duel circulation, previously congested tissues, and when flow is reestablished after infarction has occurred
Term
White Infarcts
Definition
occur with arterial occlusions in solid organs with end-arterial circulations, where tissue density limits the seepage of blood from adjoining patent vascular beds
Term
Septic Infarcts
Definition
infected cardiac valve vegetations embolize, or when microbes seed necrotic tissue, infarct becomes an abscess with a greater inflammatory response
Term
Bland infarcts
Definition
absence of bacterial involvement
Term
Factors affecting severity of injury due to infarction
Definition
general status of the blood and the cardiovascular system, the anatomic pattern of the vascular supply of the tissue involved (single versus dual/anastomosing blood supply), the rate of development of the occlusion, the vulnerability of the tissue to ischemia.
Term
clinical significance of infarcts as a cause of death
Definition
40% of all deaths in the US are a consequence of cardiovascular disease, with most of these deaths stemming from myocardial or cerebral infarction
Term
Shock is BEST defined as
Definition
cardiovascular collapse due to severe cardiogenic, hypovolemic or septic disease
Term
Causes of shock include all of the following EXCEPT
Definition
anemia
Term
Shock as a result of hypovolemia is LEAST likely to occur with
Definition
sepsis
Term
White infarcts are encountered in all EXCEPT
Definition
Ovary
Term
Red infarct is seen in all EXCEPT
Definition
Kidney
Term
3 causes of shock
Definition
cardiogenic, hypovolemic, and septic
Term
[image]
Definition
White Infarct
Term
[image]
Definition
Red Infarct
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