Term
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Definition
| Osteosarcoma, chondrosarcoma, Ewing sarcoma. |
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Term
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Definition
| bosselated, round-to-oval sessile tumor. skull or facial bones. Gardner syndrome. Composite of woven and lamellar bone |
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Term
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Definition
| benign, treated with radioablation. Osteoid osteoma if less than 2 cm. teens and early 20s. Men. nocturnal pain relieved by aspirin for <2cm, no pain relief when greater. Well-defined margins. Nidus surrounded by reactive bone formation. |
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Term
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Definition
| The tumor center of a osteoblastoma formation. |
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Term
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Definition
| Malignant mesenchymal tumor. Most commonly primary, solitary, intramedulary and poorly differentiated. Form bone, coarse, lace-like architecture. Triangular shadow on radiograph is Codman triangle. Genes: RB, p53, INK4a/p16 |
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Term
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Definition
| also exostosis. Benign cartilage-capped tumor with bony stalk. Associated with multiple hereditary exostosis syndrome. (EXT1/2). Knee and men common. |
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Term
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Definition
| benign hyeline cartilage. Also Ollier disease. gray-blue and translucent. C/O ring: unmineralized oval lucencies surrounded by thin rim of radiodense bone. Nodules scallop endosteum. |
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Term
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Definition
| chondromas in the medullary cavity |
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Term
| subperiosteal/juxtacortical chondroma |
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Definition
| chondroma on the surface of bone |
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Term
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Definition
| rare benign tumor. teens and men, knee. pedilection for epiphyses and apophyses. sheest of compact polyhedral chondroblasts. hyperlobulated nuclei. lace-like hyaline matric with chicken-wire mineralization. Effusions and joint dysmobility. Radiographic lucency |
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Term
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Definition
| Rarest of cartilage tumors. mistaken for sarcoma. Teens/20s, men, metaphysis of long bones. fibrous septae, areas of great cellularity at periphery of nodules. achy pain. Ecccentric lucency with sclerosis expanding overlying cortex. Simple curettage used with no risk of malignant transformation. |
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Term
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Definition
| Neolastic cartilage. Second most common malignant bone tumor. >40, men. thickens and erodes cortex. Rarely on distal exremities. Painful, progressively enlarging masses. Graded by cellularity. |
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Term
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Definition
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Term
| peripheral chondrosarcoma |
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Definition
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Term
| Conventional Chondrosarcoma |
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Definition
| Malignant hyaline and myxoid cartilage. More myxoid is more gelatinous |
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Term
| Chondroblastic Osteosarcoma |
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Definition
| Malignant cartilage is abundant in this osteosarcoma |
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Term
| Dedifferentiated Chondrosarcoma |
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Definition
| 10 of conventional that have second high-grade component |
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Term
| Clear cell chondrosarcoma |
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Definition
| osteoclast-type giant cells, sheets of large malignant chondrocytes. |
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Term
| Mesenchymal chondrosarcoma |
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Definition
| islands of well-differentiated hyline cartilage. Mimics ewing sarcoma. |
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Term
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Definition
| Fibrous cortical defects in children when smaller than 6cm. Eccentric in the metaphysis. Elongated, sharply demarcated radiolucencies with sclerosis. Storiform (pinwheel) patter of fibroblasts. |
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Term
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Definition
| Benign, localized developmental arrest. Monostotic, polyostotic, or polyostotic w/ cafe-au-lait. GNAS gene. McCune-Albright syndrome for polyostotic with cafe-au-lait. Trabeculae mimic Chinese letters. Ground glass on radiology. Bisphosphonates for pain. |
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Term
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Definition
| GNAS mutation. endocrinopathies with sexual precocity, hyperthyroidism, pituitary adenomas. Ipsilateral skin pigmentation. |
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Term
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Definition
| Collagen-producing sarcoma, also malignant fibrous histiocytoma. >=middle aged. malignant fibroblasts in herringbone storiform pattern. Permeative and lytic extending into adjacent soft tissue |
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Term
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Definition
| Similar to primitive neuroectodermal tumor PNET with less neural differentiation. translocation (11;22)(q24;q12). Clear, glycogen rich cells. Homer-Wright rosettes, diaphysis of long tubular bones. painful enlarging masses. inflammatory changes. onion-skin reactive bone. |
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Term
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Definition
| tumor cells arranged in a circle about a central fibrillary space indicative of neural differentiation. |
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Term
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Definition
| Also osteoclastoma. Monocuclear cells and multinucleated osteo-clast-type giant cells. Locally aggresive. 20-40. RANKL. limited to metaphyses in adolescents with epiphyses also in adults. Arthritis. |
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Term
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Definition
| 17p13 translocation with up-rgulated USP6. Plump uniform fibroblasts, osteoclasts, reactive woven bone (blue bone). Hemorrhagic cysts. <20, painful. Ecentric well-difined radiographically. |
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