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Pathogen/Pathogenesis
Pathogen/ (Disease, Transmission, Identification, Treatment)
37
Microbiology
Undergraduate 3
05/05/2011
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Term
Varicella Herpes Zoster
 Definition
dsDNA herpes virus. Infects respiratory epithelium first. Erupts after incubation. Production of antibodies and IgA and IgM
Term
Influenza
 Definition
-ssRNA herpesvirus. Neuraminidase and Hemagglutinin. Neuraminidase cleaves sialic acid bond between receptor/virion to release. Hemagglutinin facilitates receptor binding, internalization and release of virion content. Different H/A combination = different strain, antigenic drift/shift.
Term
Measles
 Definition
-ssRNA envelope. Enters respiratory tract/conjuctiva of eye. CD46, CD150 (B-cell, T-cell)
Term
West Nile
 Definition
West Nile Fever
Term
Yellow Fever
 Definition
Yellow Fever
Term
HIV
 Definition
+ssRNA enveloped. Direct contact. Common group M HIV1. gp120 attaches to CD4, with help from cell gp41. CD4 of T-cells. Dendritic cells possibly first infected. RNA -> DNA via RT. ssDNA -> dsDNA, translocated to nucleus and integrated via Integrase. Protease cleaves polypeptide. gag forms capsid.
Term
Rhinovirus
 Definition
Common Cold
Term
Mumps
 Definition
Mumps
Term
Rubella
 Definition
+ssRNA enveloped. Respiratory tract.
Term
Herpes Simplex 1 and 2
 Definition
Cold Sores
Term
Eppstein-Barr
 Definition
Mononucleosis (Mono,) Hepatidis
Term
Human papillomavirus
 Definition
Warts
Term
Rotavirus
 Definition
Gastroenteritis
Term
Adenovirus
 Definition
Gastroenteritis
Term
Astrovirus
 Definition
Gastroenteritis
Term
Calicivirus
 Definition
Gastroenteritis
Term
Hepatitis A
 Definition
Gastroenteritis
Term
Hepatitis E
 Definition
Gastroenteritis
Term
Polio
 Definition
Poliomyelitis
Term
Ebola
 Definition
Ebola Hemorrhagic Fever
Term
Lyssavirus (Genus)
 Definition
Rabies
Term
Corynebacterium Diphtheriae
 Definition
Airborne, gram positive bacteria. Resistant to dessication.
Infection - In respiratory tract.
Virulence - Prophage tox produces AB EXOTOXIN. Toxin circulation & absorption destroys cardiac/kidney/nervous tissue by inhibiting protein synthesis.
Term
Neisseria meningitidis
 Definition
Meningitis
Term
Bordetella pertussis
 Definition
Pertussis (Whooping Cough)
Term
Streptococcus pyogenes
 Definition
Scarlet Fever, Toxic Shock syndrome, Rheumatic Fever,
Term
Streptococcus pneumoniae
 Definition
Pneumonia, Otitis media, meningitis, bacteremia, osteomyelitis, septic arthritis
Term
Yersinia pestis
 Definition
Plague
Term
Borrelia burgdorferi
 Definition
Lyme Disease
Term
Bacillus anthracis
 Definition
Cutenaeous, Pulmonary and Gastrointestinal Anthrax
Term
Heliobacter pylori
 Definition
Gastric ulcers and stomach cancer
Term
Staphylococcus aureus
 Definition
pneumonia, toxic shock syndrome, meningitis, bacteremia
Term
Staphylococcus epidermidis
 Definition
Acne, myocarditis
Term
Vibrio cholera
 Definition
Cholera
Term
Listeria monocytogenes
 Definition
Listeriosis (meningitis, pneumonia, encephalitis)
Term
Clostridium botulinum
 Definition
Botulism
Term
Escherichia coli
 Definition
Entero problems
Term
Salmonella typhimurium
 Definition
Typhoid Fever
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