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Patho
Chapter 5
24
Nursing
Undergraduate 3
06/13/2010

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Cards

Term
What are the 3 biochemical barriers?
Definition
secretions, macromolecules, and normal bacteria flora
Term
What is the term that describes when the WBCs exit the blood vessel walls?
Definition
diapedesis, leukocyte extravation
Term
The redness in inflammation is caused by?
Definition
vasodialation and vasculare permeability
Term
What causes the heat symptom of inflammation?
Definition
increased blood flow due to vasidialation
Term
What causes swelling in inflammation?
Definition
extra fluid leakage from vascular permability
Term
What are some benefits of inflammation?
Definition
limit and control of tissue damage, prevents infection, initiates adaptive immunity, and initiates healing
Term
What isolates an infection by building a wall and confining injurious agents?
Definition
granulomatosus
Term
What molecules are released during mast cell degranulation?
Definition
histamine and chemotactic factors
Term
What are synthesized during mast cell activation?
Definition
leukotrienes, prostoglandins, platelet activating factor
Term
What does histamine do?
Definition
causes temporary, rapid constriction of smooth muscle and dilation of the post capillary venules
Term
Which histamine receptor promotes inflammation?
Definition
H1
Term
What are the 3 plasma protein systems?
Definition
complement, clotting, kinin
Term
What are the 4 functions of the products of the complement system?
Definition
opsonization, anaphylatoxic activity, chemotaxis, cell lysis
Term
What is the process by which a pathogen is marked for destruction?
Definition
opsonization
Term
What induced rapid degranulation of mast cells?
Definition
anaphylotoxins in anaphylatoxic activity
Term
What are the 4 effects of the clotting system?
Definition
stops bleeding, traps infectious organisms, localizes (traps) injurious agents to the site of inflammation, and aids in repair and healing
Term
What are both the clotting cascade and the kinin cascade activated by?
Definition
factor XII
Term
What is the final product of the kinin cascade?
Definition
bradykin
Term
What are the 4 types of inflammatory blood cells?
Definition
granulocytes (neutrophils, eosinophils, basophils), monocytes, platelets, lymphocytes
Term
How quickly do neutrophils appear at the site of inflammation?
Definition
6-12 hours
Term
What are the primary roles of neutrophils?
Definition
phagocytosis, removal of debris
Term
What products become a part of purulent exudates (pus) upon their death?
Definition
neutrophils
Term
what attracts macrophages?
Definition
chemokines released from neutrophils
Term
What are the 2 functions of eosinophils?
Definition
body's primary defense against parasites and degrades vasoactive amines (histamine)to end the inflammatory response
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