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Patho Vocab
Chapter 1,2
36
Other
Undergraduate 2
05/20/2016

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Term
Differentiation
Definition
Process by which cells become specialized.
Term
Nucleus
Definition
surrounded by the cytoplasm and generally located in the center of the cell; largest membrane-bound organelle
Term
lipids
Definition
basic component of the plasma bi-layer membrane. Responsible for the structural integrity of the membrane. Amphipathic, with a water loving and a water hating component
Term
protein
Definition
is made from a chain of amino acids, known as polypeptides. There are 20 different types of amino acids.
Term
cellular receptors
Definition
protein molecules on the plasma membrane, in the cytoplasm or in the nucleus that can recognize and bind with specific smaller molecules called ligands.
Term
plasma membrane receptors
Definition
protrude from or are exposed at the external surface of the membrane and are important for cellular uptake of ligands
Term
homeostasis
Definition
stable environment needed to regulate cellular growth and division.
Term
neurotransmitters
Definition
chemicals that allow neurons to communicate directly with the cells they innervate
Term
oxidative phosphorylation
Definition
occurs in mitochondria and is the mechanism by which the energy produced from carbohydrates, fats, and proteins is transferred to ATP
Term
passive transport
Definition
Process by which no energy is required to drive water and small, electrically uncharged particles can move easily through a semipermeable barrier; driven by osmosis, hydrostatic pressure and diffusion
Term
active transport
Definition
A process of moving large molecules into and out of the cell. Occurs across living membranes and use energy generated by cellular metabolism and have receptors that can recognize and bind with the substance to be transported
Term
solute
Definition
water and dissolved particles
Term
electrolytes
Definition
Composition of body fluids; electrically charged and dissociate into constituent ions
Term
cations
Definition
positively charged ion
Term
anion
Definition
negatively charged ion
Term
diffusion
Definition
movement of a solute molecule from area of great concentration to area of lower concentration
Term
concentration gradient
Definition
The difference between the area of higher concentration and area of lower concentration
Term
filtration
Definition
movement of water and solutes through a membrane because of a greater pushing pressure (force)on one side of the membrane than the other
Term
hydrostatic pressure
Definition
mechanical force of water pushing against cellular membrane. Partially balanced by osmotic pressure, whereby water moving out of the capillaries is partially balanced by osmotic forces that tend to pull water into the capillaries (blood pressure)
Term
osmosis
Definition
the movement of water down the concentration gradient, requiring that the membrane must be more permeable to water that to solutes and the the concentration of solutes on one side of the membrane must be greater than that on the other side so that water moves more easily
Term
osmolarity
Definition
measures the number of milliosmoles per liter of solution, or the concentration of molecules per volume of solution
Term
osmolality
Definition
measures the number of milliosmoes per kilogram of water, or the concertation of molecules per weight of water.
Term
oncotic pressure
Definition
the overall osmotic effect of colloids, such as plasma proteins
Term
tonicity
Definition
describes the effective osmolality of a solution
Term
hypotonic solution
Definition
has a lower concentration and is thus more dilute than body fluids (cell cells)
Term
hypertonic solution
Definition
has a higher concentration (cell shrinks)
Term
mediated transport
Definition
(passive and active) involves integral or transmembrane proteins with receptors that are highly specific for the substance being transported.
Term
facilitated diffusion
Definition
protein transporter moves solute molecules through cellular membranes without expending energy
Term
depolorization
Definition
the process of reversing the charge across a cell membrane (usually a NEURON), so causing an ACTION POTENTIAL. In depolarization, the inside of the membrane, which is normally negatively charged, becomes positive and the outside negative. This is brought about by positive sodium ions rapidly passing into the axon. The RESTING POTENTIAL is restored by the SODIUM PUMP mechanism.
Term
repolarization
Definition
A new action potential cannot take place until the proper electrical charge across the neuron's membrane is restored. This means that the inside of the cell needs to be negative, while the outside needs to be positive. A cell restores this state, or repolarizes itself, by turning on a protein pump in its membrane. This pump is called the sodium-potassium pump. For every three sodium ions it pumps out of a cell, it pumps in two potassium ions. The pumps do this until the proper charge inside of a cell is reached.
Term
chromosomes
Definition
A chromosome is a long, stringy aggregate of genes that carries heredity information (DNA) and is formed from condensed chromatin.
Term
mutation
Definition
Mutation is a natural process that changes a DNA sequence.
Term
tumor suppressor gene
Definition
A gene whose protein protein terminates cell proliferation, thereby inhibiting tumor formation
Term
phagocytosis
Definition
A type of endocytosis sometimes referred to as cell eating in which substances such as bacteria and cell particulates are incorporated into large vesicles or vacuoles and digested
Term
catabolism
Definition
Cellular process that provides energy by breaking down complex molecules into simpler molecules
Term
anabolism
Definition
A cellular process that uses energy to synthesize complex molecules from simpler molecules
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