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Patho Test 7- Ch. 23
n/a
26
Nursing
Undergraduate 3
07/18/2010

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Term
varicose vein
Definition
a vein in which blood has pooled
Term
chronic venous insufficiency (CVI)
Definition
inadequate venous return over a long period; this is related to varicose veins or valvular incompetence; you will get pooling of blood, hyperpigmented skin, and edema; can lead to venous stasis ulcers
Term
venous stasis ulcers
Definition
result of reduced delivery of oxygen, infection, and inflammation; cell death occurs and necrotic tissue develops into these
Term
venous thrombi
Definition
which are more common? venous or arterial thrombi?
Term
deep venous thrombosis
Definition
associated with varicose veins and CVI; may obstruct venous flow which causes increased venous pressure. you get accumulation of clotting factors/platelets and inflammation
Term
factors that promote DVT (triad of Virchow)
Definition
venous stasis (circulation not moving/static), venous endothelial damage (from trauma or medications), and hypercoagulable states (result of pregnancy or cancer)
Term
superior vena cava syndrome
Definition
progressive occlusion of the superior vena cava that leads to venous distention in the upper extremities and head; it prevents (or slows) venous return from the upper extremities and head. Usually caused by an obstruction (most commonly a tumor) pressing on SVC close to where it enters the RA
Term
hypertension
Definition
consistent elevation of arterial blood pressure
Term
primary hypertension
Definition
essential or idiopathic hypertension that's due to genetic and environmental factors; affects 92-95% of people with hypertension
Term
secondary hypertension
Definition
hypertension caused by an underlying disease process or medication that raises peripheral vascular resistance or cardiac output; ex: birth control pills, drugs
Term
isolated systolic hypertension
Definition
a sustained systolic BP that is >or=140mmHg and diastolic that's below 90mmHg; caused by increases in cardiac output, total peripheral vascular resistance, or both
Term
complicated hypertension
Definition
causes damage to walls of blood vessels; comprises the strucures and function of vessels, the heart, kidneys, eyes, and the brain; smooth muscle cells undergo hypertrophy and hyperplasia; you also get fibrosis of the tunica intima and media; Hypertrophy, angina, left heart failure, CAD, MI and sudden death
Term
malignant hypertension
Definition
rapidly progressive hypertension; diastolic pressure is usually >140mmHg; life threatening; disrupts cerebral functioning
Term
orthostatic (postural) hypotension
Definition
decrease in both systolic and diastolic blood pressure upon standing; your compensatory vasomotor response to standing is absent; you get pooling in muscle vasculature, splenic and renal beds
Term
aneurysm
Definition
localized dilation or outpouching of a vessel wall or cardiac chamber; the tension on the wall increasesaas the vessel becomes thinner, so the possiblility of rupture increases.
Term
true aneurysm
Definition
fusiform or circumferential in nature and involve all three layers of the arterial wall; you get weakening of the vessel wall
Term
false aneurysm
Definition
an extravascular hematoma that communicates with the intravascular space; usually the result of trauma; caused by a break in the wall or a dissection of the layers of the arterial wall; blood is contained at the
Term
thrombus
Definition
blood clot that remains attached to the vessel wall
Term
thromboembolus
Definition
detached thrombus that is moving in the circulation
Term
thrombophlebitis
Definition
clot attached causing an inflammatory response in a vein; inflammation of a vein accompanied by the formation of a clot
Term
embolism
Definition
bolus of matter that is circulating in the bloodstream that shouldn't be there; may be a dislodged thrombus, air bubble, amniotic fluid, aggregate of fat, bacteria, cancer cells, or a foreign substance; results in ischemia or infarction
Term
thromboangiitis obliterans (beurger disease)
Definition
immune/inflammatory disease of peripheral arteries; can eventually occlude and obliterate portions of small and medium sized arteries in the feet and sometimes in the hands; accompanied by thrombi and vasospasm of arterial segments
Term
raynaud phenomenon
Definition
characterized by attacks of vasospasm in the small areries and arterioles of teh fingers and less commonly, the toes; secondary to other systemic diseases or conditions such as collagen vascular disease (scleroderma), smoking, pulmonary hypertension, myxedema, environmental factors like cold or prolonged exposure to vibrating machinery
Term
raynaud disease
Definition
characterized by attacks of vasospasm in the small areries and arterioles of teh fingers and less commonly, the toes; primary vasospastic disease of unknown origin; endothelial damage= imbalance in vasodilators and vasoconstrictors; triggers are cold or emotional stress; maybe a genetic predisposition
Term
arteriosclerosis
Definition
chronic disease of the arterial system; abnormal thickening and hardening of the vessel walls; results in narrowing of lumen
Term
atherosclerosis
Definition
most common form of arteriosclerosis; thickening of vessel wall caused by accumulation of lipid-laden macrophages and plaque development. this is the leading cause of coronary artery disease and cerebrovascular disease
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