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Patho Flashcards Ch. 41 & 42
yeah!
96
Medical
Undergraduate 3
05/06/2008

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Term
What are the three cardinal manifestations of parkinson's disease?
Definition
Tremor, rigidity and bradykindesia
Term
What is another name for Lou Gherig's disease?
Definition
Amytropic Lateral Sclerosis
Term
What is the difference between cutaneous and deep somatic pain?
Definition
Cutaneous arises from the skin, and deep somatic arises from deep body structures like muscles, tendons, etc. Also the pain is more diffuse with deep somatic.
Term
What is usually the cause of acute pain?
Definition
Injury to body tissues.
Term
Is the pain from osteoarthritis acute or chronic?
Definition
It can be both.
Term
What is the most diabling of the cardinal symptoms of parkinson's?
Definition
Bradykinesia.
Term
What type of inherited trait is associated with migraines?
Definition
Autosomal dominant trait.
Term
What type of headach is usually misdiagnosed (self-diagnosis) as something other than a migraine?
Definition
A sinus headace.
Term
Which type of migraine is typically hereditary?
Definition
The ones with aura.
Term
What is a possible side effect of stimulation of the trigeminal nerve?
Definition
Migraine headace.
Term
What type of headaches can have remissions of months or longer only to return again?
Definition
Cluster headaches.
Term
What is the most common type of headache?
Definition
Tension headaches.
Term
What type of disease is myasthenia categorized as?
Definition
An autoimmune disease
Term
When is the peak incidence of myasthenia gravis?
Definition
Between 20 and 30 years.
Term
Is myasthenia more common in women or men? By how much?
Definition
It is 3 times more common in chicks. However, dudes have a second peak in later life.
Term
What is myasthenia thought to be attributed to?
Definition
An abnormal T-lymphocyte function. (75% have thymic abnormalities)
Term
What type of immunity is affected in myasthenia gravis?
Definition
Cell-mediated immunity
Term
What is an increased number of cells in the thymus known as?
Definition
Thymic hyperplasia
Term
What is destroyeed in myasthenia gravis?
Definition
Acetylcholine receptors, through an antibody-mediated pathway.
Term
What the heck is diplopia?
Definition
Double vision
Term
Which muscles are most affected in myasthenia gravis?
Definition
Periorbital muscles
Term
Why to patients with MG tend to steer toward soft food?
Definition
Because they have problems with chewing
Term
What might a client need during times of extreme stress like pregnancy or surgery?
Definition
Respiratory
Term
The nurse knows that during an anticholinesterase test, the doctor will administer a drug to the client. What is the drug and what is the outcome in a test that is positive for MG?
Definition
The physician will give tensilon. If they are positive for MG, there will be a dramatic improvement in weakness.
Term
How can acetylcholine antibodies be detected in the blood?
Definition
Using an immunoassay test.
Term
Is the incidence of back pain higher in men or women?
Definition
It affects both equally.
Term
What is the average age of onset for back pain?
Definition
between 30 and 50 years.
Term
What is the most critical component of the load bearing spine?
Definition
The intevertebral disc
Term
What is another word for intevertebral disc?
Definition
Nucleus pulposus.
Term
If nerve root L4 is damaged in the back, the client will feel pain on the _______ ____ ______ __ ___ ____ and numbness in the ____.
Definition
Side and front of the leg; knee
Term
If nerve root L5 is damaged in the back, the client will feel pain on the _______ ____ ______ __ ___ ____ and numbness in the ____ __ ___ ____.
Definition
Outer butt cheek and down the side of the leg; side of the calf
Term
If nerve root S1 is damaged in the back, the client will feel pain on the _______ ____ ______ __ ___ ____ and numbness in the ____ and ______ __ ___ ____.
Definition
down the middle of the butt cheek; calf and bottom of the foot.
Term
How the heck do you do a straight leg test?
Definition
Lay the patient supine and raise the leg 90 degrees. If they have pain around 60 degrees, they usually have a herniated disc.
Term
What is a defining characteristic of the limb weakness experienced with MG?
Definition
It is proximal to distal weakness.
Term
What are the major risk factors for acquiring back pain?
Definition
Heavy lifting, twisting, bodily vibration, obesity and poor conditioning
Term
What are the most commonly affected areas in terms of herniated disks?
Definition
Cervical and lumbar regions.
Term
Postencephalitic syndrome, side effect of antipsychotic drugs, toxic reaciton to chemical agent, and carbon monoxide poisoning are all causes of what disorder?
Definition
Parkinson Disease
Term
Weakness, spasticity/stiffness, impaired fine motor control, dysphagia, dysarthria and dysphonia are all symptoms of Lou Gherig's disease (ALS) occurring in which part of the brain?
Definition
UMN
Term
Fasciculations, weakness, muscle atrophy, hyporeflexia, progressive weakness/atrophy and muscle cramps are all symptoms of Lou Gherig's diseas occurring in which part of the brain?
Definition
LMN (Lateral horn)
Term
What is the most common cause of non-traumatic disability in young and middle adults?
Definition
Multiple sclerosis
Term
What is the most common cause of non-traumatic disability in young and middle adults?
Definition
Multiple sclerosis
Term
What demographic does MS affect the most?
Definition
Women of northern european descent.
Term
Presence of which allele substantially increases the risk of developing MS?
Definition
HLA-DR2
Term
In order for a diagnosis of Multiple sclerosis to be made, what must be present?
Definition
Cerebral lesion in different areas of the CNS with no other explanation, at least 3 months apart.
Term
Parashtesias, optic neuritis, doplopia, pain, abnormal gait, bladder/sex dysfunction, psychological problems and fatigue are clinical features of which condition?
Definition
Multiple sclerosis.
Term
When edema forms in the spinal cord and the tissue dies and is replaced by collagen, this is called what?
Definition
Dissolution
Term
Temporary complete loss of function below an injury is called what?
Definition
Spinal cord shock
Term
Damage to axons near the gray matter can cause what?
Definition
Central cord syndrome
Term
What sensations are affected/unaffected in anterior cord syndrome?
Definition
Motor functions are affected, but touch sensation is not.
Term
Which spinal cord injury involves the arms more than the legs and where does it occur?
Definition
Central cord injury. Occurs almost exclusively in the cervical cord. Elderly and congenital stenosis are causes.
Term
Damage to one side of the spinal cord causing loss of function on that side (flaccid paralysis), pain & temp and vibration & proprioception sensation loss from the other side is called what?
Definition
Brown sequard syndrome
Term
If there is a complete spinal cord injury at T12 or above, what will be the resulting symptoms?
Definition
Spinal reflexes will still work, but will no longer be modulated by the brain. Spastic paralysis will result.
Term
What is hypertonia?
Definition
A condition marked by an abnormal increase in the tightness of muscle tone and a recuced ability of a muscle to stretch.
Term
A client presents to the ER with a complete spinal injury at the cervical level. The nurse knows the extent of this clients injuries will probably leave him in a state known as:
Definition
Quadreplegia or tetraplegia
Term
A client presents to the ER with a complete spinal injury at the thoracic level. The nurse knows the extent of this clients injuries will probably leave him in a state known as:
Definition
Paraplegia
Term
A client presents to the ER with a complete spinal injury at the lumbar level. The nurse knows the extent of this clients injuries will probably leave him in a state known as:
Definition
Paraplegia
Term
What type of injury occurs at the time of mechanical injury and is irreversible?
Definition
Primary neurologic injury
Term
What type of injury occurs after the initial injury and promotes the spread of injury?
Definition
A secondary injury
Term
What is an exaggeraged sympathetic reflex symptom that occurs in people with T6 spinal injury at or above T6 and results in full bladder or fecal impaction?
Definition
Autonomic visceroplexia
Term
Why is nasal stuffiness an important sign to watch for in a client with a T6 or above spinal injury?
Definition
It is a cue that they could have autonomic visceroplexia. Other symptoms of this are extremely high blood pressure, headache, impaired thought process and changes in levels of consciousness.
Term
What part of brain matter does vasogenic cerebral edema affect?
Definition
White matter.
Term
What type of cerebral edema occurs when the BBB is disrupted?
Definition
Vasogenic. This disruption allows fluid to escape into the ECF that surrounds brain cells.
Term
This type of cerebral edema occurs with tumors, prolonged ischemia, hemorrhage, brain injury, and infectious processes that impair the function of the BBB and allow water and plasma proteins to leave the capillaries and move into the interstitium.
Definition
Vasogenic
Term
What type of cerebral edema affects the grey matter?
Definition
Cytotoxic edema
Term
What is the normal range of ICP?
Definition
0-15mmHg
Term
Above what level of ICP will you begin to see signs of swelling.
Definition
20mmHg
Term
Direct contact phenomenon is an example of which type of injury?
Definition
A primary injury.
Term
What is the name of the phenomenon that occurs when impact trauma occurs to the head and the brain slams up against the front of the skull, rebounds, and slams against the back of the skull?
Definition
Coup-Contacoup
Term
Contusions, lacerations and hemorrhage are examples of which category of primary injury?
Definition
Focal injuries
Term
Concussion and diffuse axonal injury are what type of primary injury?
Definition
Diffuse
Term
When are the signs of MG the worst?
Definition
With effort and as the day progresses.
Term
Enlargement of the CSF compartment occurs with which disorder?
Definition
Hydrocephalus
Term
This type of hematoma has a rapid onset.
Definition
Epidural hematoma
Term
The gelatinous center of the intevertebral disc is called what?
Definition
The nucleus propulsus
Term
The fibrinous ring surrounding the nucleus fibrosis is called what?
Definition
Annulus fibrosis
Term
How come in an epidural bleed the pupils will be affected on the same side, but the body is affected on the opposite side?
Definition
Because the cranial nerves to not cross over like the somatic nerves do.
Term
When is the prognosis excellent with an epidural bleed?
Definition
When it is caught before loss of consciousness occurs.
Term
When a client has changes in levels of consciousness and complains of headaches over a number of days, the nurse might suspect. . .
Definition
Subdural hematoma
Term
What is the most sensitive and important indicator of a patient's neurological status?
Definition
Level of consciousness
Term
What is a sign that a patient is beginning to go into cheyne-stokes's respirations?
Definition
Yawning and sighing
Term
Describe cheyne-stokes breathing.
Definition
an abnormal pattern of breathing characterized by oscillation of ventilation between apnea and hyperpnea, to compensate for changing serum partial pressures of oxygen and carbon dioxide.
Term
What is a stemic type of breathing characterized by sustained, regular, rapid breathing?
Definition
Neurogenic
Term
Which cranial nerve does doll's eye phenomenon assess?
Definition
Cranial nerve II
Term
Which type of posturing indicates a lesion of the cerebral hemisphere?
Definition
Decorticate
Term
Which type of pusturing indicates a midbrain or upper brainstem?
Definition
Decerebrate posturing
Term
If a person is in decorticate posturing when you leave them, and you return and they are in decerebrate posturing, what does this indicate?
Definition
That they are worse off.
Term
What is the most common type of stroke and what is the prevalence?
Definition
Ischemic stroke. It accounts for 80% of strokes.
Term
What is the most common cause of secondary brain injury?
Definition
Ischemia
Term
What is the clinical term for a central core of dead or dying cells in the brain, surrounded by and ischemic band of minimally perfused cells?
Definition
Penumbra
Term
What are Focal ischemic cerebral neurologic deficits that last for less than 24 hours (usually less than 1 to 2 hours).
Definition
Transient eschemic attacks
Term
What is a zone of penumbra without centaral infarction?
Definition
Transient ischemic attack
Term
Atherosclerotic disease of cerebral vessels and cmboli are risk factors for what conditions?
Definition
TIA and stroke
Term
Which age group is more at risk for epidural hematoma?
Definition
Young persons, because the brain is not sufficiently attached to the dura.
Term
Rupture of an aneurism results in which type of brain hemmorhage?
Definition
A subarachnoid hemorrhage
Term
What is a scale for assessing level of consciousness in a person with brain injury?
Definition
Glasgow scale
Term
What is the most frequently fatal stroke?
Definition
A spontaneous hemorrhage into the brain substance
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