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Patho Ch. 25
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58
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Undergraduate 4
04/22/2012

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Term
What are conducting airways lined with?
Definition
pseudostratified ciliated columnar epithelium
Term
What's pseudostratified ciliated columnar epithelium contain?
Definition
serous glands and mucus-secreting goblet cells
Term
What's special about the pharynx?
Definition
only opening between the nasal and mouth openings and the lungs
Term
What's the larynx do?
Definition
connects pharynx with trachea
Term
What's the epiglottis?
Definition
thin, leaf-shaped structure that aids in covering the larynx during swallowing to prevent food and fluids from entering the larynx
Term
What are the functions of the epiglottis?
Definition
associated with speech
associated with protecting the lung by preventing the entrance of substances other than air
Term
What's the trachea?
Definition
continuous tube that connects larynx and major bronchi of lungs
walls are supported by cartilage
Term
What is formed when the trachea divides?
Definition
right and left primary bronchi, which enters the lung through a slit called the hilus
Term
What are bronchioles encircled with?
Definition
a spiraling layer of smooth muscle fiberes
Term
What causes bronchoconstriction?
Definition
parasympathetic
Term
What causes relaxation of muscle?
Definition
sympathetic
Term
What are lobules?
Definition
functional units where gas exchange takes place
Term
What is each lobule supplied with?
Definition
structures that provide for both gas exchange and circulation of blood
Term
What do gas exchange structures consist of?
Definition
respiratory bronchiole, alveolar duct, and alveoli sacs
Term
What are alveolar sacs?
Definition
cup-shaped, thin-walled structures seperated from each other by alveolar septa
Term
What are alveolar structures composed of?
Definition
three types of cells: type 1 alveolar cells, type 2 alveolar cells, and alveolar macrophages
Term
What are type 1 alveolar cells?
Definition
flat, squamous, epithelial cells, across which gas exchange takes place
Term
What are type 2 alveolar cells?
Definition
produce surfactant, a lipoprotein substance that decreases the surface tension within the alveoli
allows for greater ease of lung inflation and helps prevent collapse of smaller airways
Term
What do alveolar macrophages do?
Definition
responsible for removal of offending matter from alveolar epithelium
Term
What's ventilation?
Definition
mechanical movement of gas or air into and out of lungs
Term
When measuring respiratory pressure, what is the value of atmospheric pressure?
Definition
zero
Term
What's Boyle's law state?
Definition
pressure of a gas will vary inversely with the volume of the container, provided the temperature is kept constant
Term
How do gases move?
Definition
from an area of greater pressure to one of lesser pressure
Term
What's the law of partial pressures?
Definition
total pressure of mixture of gases is equal to the sum of the partial pressures of the seperate gases in the mixture
Term
What is water vapor pressure?
Definition
air in lungs is completely saturated
Term
What's the pressure of water vapor at normal body temperature (98.6)?
Definition
47 mm Hg
Term
What must be included in the sum of the total pressure of the gases in the alveoli?
Definition
water pressure
Term
What's lung compliance?
Definition
describes ease with which lungs can be inflated
refers to change in lung volume that occurs with a given change in respiratory pressures
Term
What's used to measure respiratory volumes?
Definition
spirometer
Term
What's tidal volume(TV)?
Definition
500 ml
amount of air that moves in and out of lungs during normal breathing
Term
What's inspiratory reserve(IRV)?
Definition
3000
maximum amount of air that can be inspired in excess of normal tidal volume
Term
What's expiratory reserve(ERV)?
Definition
1200 ml
maximum amount that can be exhaled in excess of normal tidal volume
Term
What's vital capacity(VC)?
Definition
4700 ml
measure of respiratory reserve, amount of air that can be inhaled and forcibly exhaled in a single breath
Term
What's the vital capacity equation?
Definition
VC = TC+ERV+IRV
Term
What's residual volume(RV)?
Definition
1200 ml
amount of air always remaining in lungs
Term
What's minute volume?
Definition
amount of air that is exchanged in 1 minute
Term
What's minute volume determined by?
Definition
metablolic needs of body
Term
What's minute volume equal to?
Definition
tidal volume multiplied by the respiratory rate
500 ml (TV) X 12 breaths/min (respiratory rate) = 6000 ml (minute volume)
Term
What's tidal volume and rate of breathing determined by?
Definition
ease of lung expansion (compliance) and the effort needed to move air through the conducting airways
Term
What's dead air space?
Definition
air moved with each breath but doesn't participate in gas exchange
Term
What are the two types of dead air space?
Definition
that contained in the conducting airways (anatomic)
that contained in the respiratory portion of the lung (physiological dead space)
Term
What's the volume of dead air space?
Definition
fixed
approximately 150-200 ml
Term
What's diffusion?
Definition
alveoli gases diffuse across alveolar-capillary membrane, moving from an area of high concentration to one of lower concentration
Term
What four factors is the diffusion of gasses in lung influenced by?
Definition
surface area available for diffusion
thickness of alveolar-capillary membrane through which gases diffuse
characteristics of the gas
difference between partial pressure of gas on either side of the membrane
Term
What is the dual blood supply of lungs?
Definition
bronchial and pulmonary circulations
Term
What's the pulmonary circulation do?
Definition
provides for gas exchange function of the lungs
Term
What's the bronchial circulation do?
Definition
provides lung with blood to meet its nutritional needs
Term
What's the function of the pulmonary circulation?
Definition
facilitate gas exchange
there must be a continuous flow of blood through the respiratory portion of the lungs
Term
What are the pulmonary vessels?
Definition
thinner and more compliant that those in the systemic circulation, and the pressures in the pulmonary systems are much lower
Term
What's the gas exchange properties of the lung?
Definition
dependent upon the matching of ventilation and perfusion, so there are equal amount of air and blood entering the respiratory portion of the lungs
Term
What are the two factors that may interfere with matching of ventilation and perfusion?
Definition
hypoventilation and shunt
Term
What's shunt?
Definition
refers to blood that moves from the venous to the arterial system without going through the ventilated portion of the lung
Term
What's respiratory shunting of the blood result from?
Definition
destructive lung disease, which impairs ventilation or from heart failure in which there is interference with the movement of blood through sections of the lungs
Term
What's the control of respiration?
Definition
movement of muscles controlling respiration requires continuous input from the nervous system
Term
What's the activity of the respiratory center regulated by?
Definition
input from other neural centers and by blood gases and blood pH
Term
What do chemoreceptors monitor?
Definition
tissue needs for oxygen delivery and removal of carbon dioxide
respond to changes in these blood gases and pH
Term
Where are the chemoreceptors for monitoring changes in carbon dioxide located?
Definition
medulla, near the respiratory center
Term
What are arterial oxygen levels monitored by?
Definition
peripheral chemoreceptors located in the carotid and aortic bodies
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