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Patho 312: Alterations in Immunity and Inflammation
Overview of how immune system operates, and immune dsyfunction including allergic reactions, autoimmunity, and foreign tissue attack
18
Science
Undergraduate 3
09/26/2009

Additional Science Flashcards

 


 

Cards

Term

 

 

 

Hypersensitivity

Definition

 

  • An unfavorable response to antigen-antibody complex.
  • Usually follow family genetic lines
Term

 

 

Four types of immune response

Definition
  1. Type I- IgE mediated reactions
  2. Type II-Tissue specific reaction
  3. Type III-Immune complex-mediated
  4. Type IV-Cell-Mediated, not antibody (delayed)
Term

 

 

Allergies

Definition

 

 

 

A type of exaggerated response

Term

 

 

 

Autoimmunity

Definition

 

 

 

A misdirected response against the host

Term

 

 

 

 Alloimmunity

Definition

 

 

Attacks on beneficial foreign tissues like transplants or transfusions

Term

 

 

Anaphylaxis

Definition

 

 

A type of allergic reaction that is severe and rapid. Can be systemic or cutaneous. Symptoms-itching, vomiting, diarrhea, respiratory stress, shock or death.

Term

 

 

Allergen

Definition

 

 

A type of environmental antigen

Term

 

 

People who have severe allergies typically produce more ______ antibodies and is usually genetic.

Definition

 

 

IgE

Term

 

 

Review: Name the five antibody isotypes with known functions.

Definition

 

 

 

IgA, IgD, IgE, IgG, IgM

Term

 

 

Review:The "Ig" prefix in IgA stands for ________, another name for antibody.

Definition

 

 

Immunoglobulin

Term

 

 

 

Name four types of IgE-mediated reactions

 

 

 

 

Definition
  1. Allergic asthma
  2. Hives
  3. Hay fever
  4. anaphylactic shock
Term

 

 

Epinephrine

Definition

 

Hormone that acts as the primary control mechanism for the inflammatory response (by binding to receptor sites on the mast cells-targeting cells of inflammation and controlling the release of inflammatory mediators.)

Term

 

 

Review: Where is epinephrine manufactured in the body?

Definition

 

 

 

Adrenal Cortex-The term epinephrine is derived from the Greek roots epi- and nephros, and literally means on the kidney.

Term

 

 

 

H1 (Histamine 1)

Definition

 

 

These are a type of receptor on host cells that cause bronchial constriction, increased vascular permeability, vasodilation and edema.

Term

 

 

 

H2 (Histamine 2)

Definition

 

 

Type of receptor on some cells that create a system that stops degranulation like on Regulatory T cells.

Term

Review: Regulatory T cells: What do they do?

Definition

 

(sometimes known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self-antigens.

Term

 

Exposure to large amount of antigens releases what type of antibody?

a. IgA

b. IgB

c. IgE

d. IgM

Definition

 

 

 

c. IgE

Term
Mast cells become sensitized when:
Definition
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