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Patho 2 test- HF & Hyperlipide
drug description
7
Medical
Undergraduate 3
10/15/2008

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Cards

Term
Fibric acid derivatives
Definition

Gemfibrozil DECREASES: high triglycerides, LDL's, cholesterol productin, sysnthesis of triglycerides. INCREAES: Cholesterol excretion AE's: thromocytopenia, blurred vision, rash

 

Hyperlipidemia  

Term
Nicotinic acid
Definition

Niacin B vitamin-water souble, decreases triglycerides, increases HDLS, used with other meds AES: vasodilation + flushing lrg doses are toxic, epigastric discomfort, TAKE ASPRIN 1/2 HR BEOFRE TO DETER FLUSHING

 

Hyperlipidemia  

Term
Nitates
Definition
Nitroglycerine
venous & aterial vasodilators decrease afterload,
USES: hf pt with ischemic heart dieases
AE's: Hypo, head ache
Term
Digitalis
Definition
Digoxin
INCREASES: cardiac contractility, force and strength
DECREASES: HR
NARROW WINDOW .5-2 TOXIC ABOVE 2
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Dig toxicity: EARLY nauease, annorexia, confusion. LATER cardiac dysrthimas, brady tachy, AV block, visual distrubances.

MONITOR AES-60 sec apical hold if below 60 greather then 120
Term
Diuretics
Definition
Decreases preload, loop diuretics contain sulfa and work on loop of henle.(lasix)

Potassium sparing diurtics-act on distal tubing-(spironlactone)
Term
Statins
Definition

Lovastatin DECREASES: lipid lvls-interfers with lipid sythesis. inhibits enzymes, lowvers LDL and totalt blood CHOlesterol AES: liver function, myalgia, photosensitvoty, myopathy(esp wit niacin). check liver and kidney function

 

Hyperlipidemia  

Term
Bile Acid binding resin
Definition

Cholestyramine (questran) Lower LDL release in bowels-drug of choice when lifestyle not enough--mix with beverage AES-GI EFFECTS (fecal impactment, diarrhea, vommiting)

 

Hyperlipidemia 

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