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Patho 2 test- Antibiotics
antibiotics used and info
10
Medical
Undergraduate 3
10/15/2008

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Term
Penicillins
Definition
Beta lactrim ring
Broad spectrum (gram +, -)
Bactericiadal
Uses: RESP, GI, GU, SKIN INFECTIONS

AE'S: Fatal anaphylaxis- observe for min 30

Drug interactions- increased with PROBENICID- synergestic effect blocks pcn excretion

may increase NA and K

Give 1 hr before or 2hr after meals

PCN G Im, Iv
Term
General Antibiotics
Definition
Superinfection-vaginities,thrush, colitis-overgrowth in GI supression of normal flora- treated with vancoymicin

Nausea/Vomitting/Diarrhea/Nephrotoxicity (ceph and mycins)/Neurotixicty (confusuin, hallunations)/Serum sickness (hives, fever, myalagia)
Term
Metronidazole (Flagyn)
Definition
Treatment of Bacteria GI infections

Given with colon surgery or treat C.DIFF
Term
Cephalosporins
Definition
"cef or Ceph"
Bacteriacidal-broad
beta lactrim ring
Gram +, - 4 generations 1st + 4th more -

USES: Surgical prophlaxis-resp, skin, gu, bone, jin, blood infections

AE's: Hypersensitivity-hives rash increased bleeding

Nursing Im (NI)-realted to PCN-with food or milk, increased risk of clotits and nephrotoxicity
Term
Aminoglycosides
Definition
"mycin"-Gentamycin
NO MORE THEN 10 DAYS
Bacteriacidal-broad
IM/IV serious systemic gram -
PO to sterilize GI tract (not absorbed)

BIG GUN

AE's serious--neph, oto neurtoxicity, be careful with renal impaired therapeutic close to toxic

Peak 30-60min
Trough before dose
Term
Fluroquinolones
Definition
"___Floxacin"- Ciprfloxacin
Bacterialcidal-broad

Uses: UTI,URI,Gonorrhea

NI: by po, encourage fluids, avoid sun, NOT FOR KIDS-join damage
Term
tetracyclines
Definition
"___cycline"
BacteriSTAIC-broad

USES: unusual disease- cholera, typus, rocky mt spotted fever, stds-ancne prevention

DO NOT give to- renal impaired, pregnet, and children, leaves stains teeth and bones

Give with food NO DAIRY!!!(prevents absoption)

avoid sun and throw away when done
Term
Sulfanomides
Definition
Bactrim
1st synthetic-not widely used
Bateriastsic-broad
UTI's and Burns

Not for: Renal impaired pregnet, children

ASK ALLERGIES

Cross sensitivity with thiazide and anti-diabetic drugs

give on EMPTY STOMACH
FLUIDS OR CRYSTAL FORMATION
Term
Macrolides
Definition
Thromycin-Erthromycin
Bacteriacidal/static-broad

Uses: resp, skin, legionnaires disease, staph, group A strep

excreted by liver-- no liver diesase

AE's Gi distress

NI-hepatoxicty- EMPTY STOMACH

Z PACK!!! 5 days
Term
Vancomycin
Definition
Misc. Antimicrobial agent
Bactericidal GRAM +, SERIOUS INFECTIONS ONLY MRSA

Usally IV-slow 1-2 hr avoid REDMAN SYNDROM

hep,oto toxic
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