Term
| non-endocrine, from Rathke’s pouch, causes compression sx→panhypopituitism |
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Definition
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|
Term
| Most common pituitary adenoma |
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Definition
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Term
| stress overwhelms glands→glucocort withdrawal, inadequate dose during stress, shock or DIC (blood clotting), waterhouse-friederichsen syndrome (bacteremia from meningococcal) |
|
Definition
| Acute Adrenal Cortical Insufficiency |
|
|
Term
| iatrogenic, autoimmune, TB, ACTH deficiency |
|
Definition
| Chronic Adrenal Cortical Insufficiency (Addison's) |
|
|
Term
| 1) iatrogenic, 2) adrenal tumor, 3) ectopic ACTH-secreting tumor |
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Definition
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|
Term
| aldosterone-secreting adenoma; hypertension, hypokalemia, low renin |
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Definition
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Term
| catecholamine secreting tumor of adrenal medulla; dx by urinary catecholamines and metanephrines; tx with adrenergic blockers, metyrosine (synthesis inhibitor) |
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Definition
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Term
| geographically variable; due to iodine deficiency, goitrogens (cruciferous vegs, soy), inborn errors of metabolism; causes compressive sx but euthyroid state; variably sized follicles filled with colloid |
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Definition
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Term
| cold or hot; few mature follicles that are oxyphilic (acidophilic) |
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Definition
|
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Term
| most common, best prognosis; spreads lymphatically; radiation is significant risk factors; diagnosed by cytology→psammoma body and ‘orphan annie’ nuclei |
|
Definition
| PTC (Papillary Thyroid Carcinoma) |
|
|
Term
| good prognosis; spreads via vasculature; diagnosed by histology→small follicles with little colloid and requires invasion of |
|
Definition
| Follicular Thyroid Carcinoma (FTC) |
|
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Term
| neuroendocrine carcinoma of C-cells; can be hereditary (RET mutation); produce amyloid which deposits in the gland; metastasizes via lymphatics and vascular |
|
Definition
| Medullary Thyroid Carcinoma (MTC) |
|
|
Term
| very aggressive→kills by invasion of airway; cellular necrosis |
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Definition
| Thyroid Anaplastic Carcinoma |
|
|
Term
| better prognosis than anaplastic; flow cytometry to rule out anaplastic |
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Definition
|
|
Term
| histo shows tall columnar cells and decreased follicle size with ‘scalloping’ pattern |
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Definition
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|
Term
| autoimmune, increased risk of developing thyroid lymphoma, Auto-Abs to peroxidase, thyroglobulin, TSH receptor; histo shows lymphoid infiltrate of lymphoid and plasma cells |
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Definition
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|
Term
| post-infectious inflammation, presents painful with fever, no auto-Abs; histo shows granulomatous inflammation (multi-nucleated massive cells), disruption of follicular epithelium & loss of colloid |
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Definition
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|
Term
| high Ca, high PTH, low phosphous; usually asymptomatic; “painful bones, renal stones, abdominal groans, and psychic moans” |
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Definition
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