Term
| _________, which is chemically related to the pesticide DDT, is selectively and severely toxic to the adrenal cortex. |
|
Definition
|
|
Term
| Mitotane is used in the treatment of which type of cancer? |
|
Definition
| adrenocortical carcinoma (which is inoperable) |
|
|
Term
| _________ catalyzes the hydrolysis of circulating asparagine to aspartic acid and ammonia, which deprives cells of the asparagine necessary for protein synthesis...leading to cell death. |
|
Definition
|
|
Term
| L-Asparaginase is used in the treatment of which type of cancer? |
|
Definition
| acute lymphocytic leukemia |
|
|
Term
| What is photodynamic therapy (PDT)? |
|
Definition
| Treatment that involved the administration of a photosensitizing chemical, usually a porphyrin, with subsequent exposure to light. Cellular damage occurs due to the production of free radicals. |
|
|
Term
| Which agent is the only PDT approved drug that's used in treatment of esophageal cancer and non-small cell lung cancer? |
|
Definition
| porfimer sodium (Photofrin) |
|
|
Term
| What wavelength and type of light is used in PDT? |
|
Definition
| 630 nm wavelength laser light |
|
|
Term
| A __________ is a proteinase complex responsible for the degredation of most intracellular proteins, including proteins crucial to cell cycle regulation and apoptosis. |
|
Definition
|
|
Term
| _________ is an organoboron compound and the first proteasome inhibitor to undergo clinical trials in the treatment of multiple myelomas who have received at least 2 prior regimens. |
|
Definition
|
|
Term
| The effects of bortezomib can be blocked by what? |
|
Definition
|
|
Term
| What is arsenic trioxide (Trisenox) used for? |
|
Definition
| acute promyelocytic leukemia |
|
|
