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Part 2: Chapter 17
Upper Motor Neuron Control of the Brainstem & Spinal Cord
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Undergraduate 2
10/20/2014

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Term
Where is the primary motor cortex located?
Definition
in the precentral gyrus & the paracentral lobule
Term
What is the difference between the corticobulbar tract and the corticospinal tract?
Definition
corticobulbar: axons terminate in the brainstem
corticospinal: axons terminate in the spinal cord
Term
decussate
Definition
to cross the midline
Term
lateral corticospinal tract
Definition
the tract where a large majority of the axons in the pyramidal tract cross the midline at the caudal end of the medulla to enter the lateral columns of the spinal cord on the opposite side
Term
ventral corticospinal tract/anterior corticospinal tract
Definition
the 10% of axons in the pyramidal tract that enter the spinal cord without crossing the midline; axons terminate either ipsilaterally or bilaterally
Term
2 aspects of muscle use correlated with the activity of primary motor neurons
Definition
1. the magnitude of the force produced by muscles
2. the direction of the force produced by muscles
Term
The activity of a number of different muscles is directly facilitated by _____
Definition
the discharges of a given upper motor neuron
Term
muscle field
Definition
the peripheral muscle group controlled by a specific upper motor neuron
Term
The activity of the upper motor neurons in the cortex controls _____, rather than individual muscles
Definition
movements
Term
How does the premotor cortex influence motor behavior indirectly?
Definition
through extensive reciprocal connections with the primary motor cortex
Term
How does the premotor cortex influence motor behavior directly?
Definition
via axons that project through the corticobulbar & corticospinal pathways to influence local circuit & lower motor neurons of the brainstem & spinal cord
Term
Rather than directly commanding the initiation of a movement, the premotor neurons appear to encode the _____
Definition
intention to perform a particular movement
Term
mirror motor neurons
Definition
a subset of neurons that respond not just in preparation for the execution of particular movements, but also when the same action is being observed
Term
Is there a difference in the response of mirror motor neurons when an action is being pantomimed versus being legitimately carried out?
Definition
mirror motor neurons respond much less well when actions are pantomimed without the presence of a behavioral goal
Term
Broca's area
Definition
critical for the production of speech; a rostral division of the lateral premotor cortex; has a special role in organizing vocal tract articulators that are involved in the production of speech sounds
Term
How is the medial premotor cortex different from the lateral area?
Definition
medial: specialized in selection of movements with an internal cue ("spontaneous movements")
lateral: specializes in selecting movements with an external cue
Term
upper motor neuron syndrome
Definition
damage to the descending motor pathways anywhere along the trajectory of the upper motor neurons from the cerebral cortex to the lower end of the spinal cord
Term
signs & symptoms of upper motor neuron syndrome
Definition
weakness, spasticity, increased tone, hyperactive reflexes, Babinski's sign, loss of fine voluntary movements
Term
signs & symptoms of lower motor neuron syndrome
Definition
weakness, paralysis, decreased reflexes, hypoactive reflexes, decreased tone, fasciculations, fibrillations, severe muscle atrophy
Term
spinal shock
Definition
the initial period of hypotonia after upper motor neuron injury; reflects the decreased activity of spinal circuits suddenly deprived of input from the motor cortex & brainstem
Term
Babinski sign
Definition
extension of the big toe/fanning of the other toes in response to stroking the sole of the foot; normal individuals should curl their toes as a response
Term
Why is the Babinski sign apparent in normal human infants?
Definition
their corticospinal pathway is not totally formed yet
Term
What is the spasticity symptom of upper motor neuron syndrome?
Definition
increased muscle tone, hyperactive stretch reflexes, & oscillatory contractions/relaxations of muscles in response to muscle stretching
Term
decerebrate rigidity
Definition
extensive upper motor neuron lesions may be accompanied by rigidity of the extensor muscles of the leg & the flexor muscles of the arm
Term
Spasticity represents an abnormal increase in the _____ of the spinal cord stretch reflexes due to loss of descending suppression
Definition
gain
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