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Parasitology I and II
Intro and Intestinal parasites
46
Medical
Professional
04/27/2009

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Term
2 important characteristics of parasitic taxonomy
Definition
ALL are eukaryotes and significant diversity
Term
2 major imported parasitic infections
Definition
Malaria (plasmodium) and Schistosomiasis
Term
3 minor imported parasitic infections
Definition
Leishmaniasis (troops from middle east), trypanosomiasis, filariasis
Term
2 parasites that can penetrate the skin
Definition
both helminths: schistosomes, hookworms
Term
definitive host
Definition
harbors adult helminth or sexual protozoan (Eugene's mom)
Term
intermediate host
Definition
harbors larval helminth or asexual protozoan
Term
reservoir host
Definition
different species that harbors parasite
Term
zoonosis
Definition
lower vertebrate disease transmissible to humans
Term
diagnostic method for vast majority of parasite infections
Definition
microscopy
Term
Ova and parasite exam of poop
Definition
intestinal parasites, examine w/in 30 min-2 hours, wet mounts, try to separate eggs from feces, can do stains
Term
perianal specimens
Definition
dx for pinworms, use scotch tape on the hole
Term
sigmoidoscopy
Definition
useful for entamoeba histolytica
Term
UG specimens
Definition
trichomonas vaginalis and schistosomes
Term
blood films
Definition
dx of malaria, trypanosomiasis, fliariasis, and leishmaniasis
Term
thin film
Definition
small drop of blood near one end, do the slide thingy and then fix with methanol
Term
thick film
Definition
3-5 small drops of blood together then spread
Term
dx by examining CSF
Definition
Naegleria, toxoplasma
Term
liver abcess biopsy
Definition
entamoeba
Term
lymph node biopsy
Definition
toxoplasma leishmania
Term
muscle biopsy
Definition
trichinella
Term
problems with antiparasitic drug treatments
Definition
parasites are eukaryotic, too much diversity, resistance common, and limited spectrum of available agents --> prophylaxis is important to do
Term
intestinal protozoa are characterized by 2 things:
Definition
trophozoite (pathologic) and cyst(transmission)stages
Term
intestinal protozoan parasite transmission
Definition
fecal-oral route typically via contaminated water
Term
life cycle for intestinal protozoan parasites
Definition
ingest cyst, excystation in stomach/bowel releases trophozoites, trophs divide by binary fusion, eventually form cysts and are contagious
Term
fecal-oral; bloody diarrhea; w/ localized necrosis of large intestine
Definition
entamoeba histolytica
Term
bloody diarrhea w/ a liver abcess
Definition
extraintestinal amebiasis
Term
rounded trophozoites that look like an eye and are destroyed by preservatives
Definition
entamoeba histolytica
Term
treatment for entamoeba infection
Definition
Metronidazole (or tinidazole) but NOT for preggers, and shoudl treat asymptomatic carriers with iodoquinol or paromomycin
Term
Entamoeba dispar
Definition
morphologically indistinguishable from E. histolytica so IMPORTANT
Term
fecal-oral, flagellated; malodorous watery diarrhea with 10 day incubation period
Definition
giardia lamblia
Term
went camping but treated water with chlorine still got sick
Definition
giardia lamblia
Term
trophozoites stain turqoise, can swim and look like a face
Definition
giardia
Term
treatment of giardia
Definition
Metronidazole or tinidazole; remember, dont give metro to pregnant women
Term
child under 5; profuse watery diarrhea with cramping; one week incubation; did a modified acid-fast stain
Definition
cryptosporidium
Term
AIDS patient with up to 50 stools per day
Definition
cryptosporidium
Term
tx for cryptosporidium
Definition
ORT but can give nitazoxanide to children, AIDS patients need retroviral therapy
Term
Most common cryptosporidium species
Definition
C. parvum
Term
Isospora belli and Cyclospora cayetanensis
Definition
similar to Crypto life cycle, transmission and symptoms; even do a modified acid-fast stain; cyclospora (round, 8-10 micros), isospora (oval, 15-25 micros) and NO person-person transmission
Term
tx for isospora and cyclospora
Definition
trimethoprim sulfoxide (bactrim)
Term
oocysts resemble normal fecal yeasts on modified acid-fast stain
Definition
cryptosporidium
Term
ciliate, pig reservoir, institutional outbreaks; huge macronucleus in large cysts
Definition
Balantidium coli
Term
tx of balantidium coli
Definition
tetracycline
Term
UG parasite, symptomatic especially in females, acquired by sex; homogenous watery vaginal discharge
Definition
Trichomonas vaginalis
Term
colpitis macularis = strawberry cervix = patchy erythmatous lesions of cervix
Definition
trichomonas vaginalis
Term
detection of mobile trophozoites in pap smears or vaginal discharge
Definition
T. vaginalis
Term
tx of trichomonas vaginalis
Definition
metronidazole or tinidazole; treat both partners
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