Term
|
Definition
Cervical cancer
Anal cancer
Head and neck cancer
Nasopharyngeal cancer
Not smoking predisposed |
|
|
Term
|
Definition
NHL – Burkitts, immunoblastic and primary CNS
High grade lymphomas
Die within weeks to months
Kaposi’s sarcoma
Cervical cancer
Above all are AIDs defining illnesses
Increased incidence of Hodgkin’s lymphoma |
|
|
Term
Human Herpesvirus-8
(KS-associated herpesvirus |
|
Definition
Kaposi's sarcoma (Mediterranean and African men)
rare B-cell Lymphoma |
|
|
Term
|
Definition
adult T-cell leukemia
(Caribbean) |
|
|
Term
|
Definition
| hepatocellular carcinoma (HCC) |
|
|
Term
|
Definition
Burkitt’s lymphoma in Africans
Anaplastic nasopharyngeal carcinoma in Chinese people
Hodgkin’s Lymphoma in US, South Americans and Europeans
Oral hairy leukoplakia (wart like tongue lesion) |
|
|
Term
|
Definition
| myelodysplastic syndrome, leukemia |
|
|
Term
| heterocyclic aromatic amines |
|
Definition
overcooking meat
associated with breast and colon CA
tobacco and mine workers: bladder CA |
|
|
Term
| smoked, pickled and salted foods. rubber industry |
|
Definition
|
|
Term
Aluminum production
Coal gasification
Hematite mining
Paint
Tobacco, arsenic, asbestos, crystalline silica, benzo (a) pyrine, beryllium, bis (chloro) methyl ether, 1,3-butadiene, chromium VI compounds, coal tar and pitch, nickel compounds, soots and mustard gas |
|
Definition
|
|
Term
| chemicals assoc with colon CA |
|
Definition
Asbestos
Heterocyclic amines |
|
|
Term
| chemicals associated with hepatocellular carcinoma |
|
Definition
Aflatoxin
Vinyl chloride
Tobacco
Alcoholic beverages
Thorium dioxide |
|
|
Term
| chemical associated with prostate CA |
|
Definition
|
|
Term
|
Definition
| in presence of EtOH is associated with oral cavity, liver, and breast CA |
|
|
Term
|
Definition
| with EtOH and tobacco, is associated with lung CA |
|
|
Term
| Nitroquinone oxoreductase |
|
Definition
| linked to leukemia when combined with benzene |
|
|
Term
| CAs associated with tobacco |
|
Definition
Oropharyngeal
Laryngeal
Esophageal
Lung
Stomach
Pancreatic
Kidney
Bladder |
|
|
Term
| prostate specific antigen (PSA) |
|
Definition
| screening test for prostate CA, monitor response to prostate CA tx |
|
|
Term
| Prostatic Acid Phosphatase (PAP) |
|
Definition
| ID's advanced prostate CA,not elevated in early dz, and monitors response to tx |
|
|
Term
| Lactate Dehydrogenase (LDH) |
|
Definition
| non-specific monitoring of inflammation |
|
|
Term
|
Definition
| monitoring patients with neuroblastoma, carcinoid, pancreatic islet cell tumor, pheochromocytoma, and medullary carcinoma of the thyroid. Seminoma, GI tract, and Wilm’s tumor |
|
|
Term
|
Definition
| Disorders of cholestasis and bone disease; commonly checked |
|
|
Term
| Gamma-Glutamyl Transferase (GGT) |
|
Definition
liver disease, helps identify with concomitant bone disease or pregnancy
Cancer – Melanoma, renal cell carcinoma, breast and lung |
|
|
Term
|
Definition
| Monitoring SCC of Head and neck, cervical, esophageal, lung, skin, and anus. Also present in ovarian cancer |
|
|
Term
| Carcinoembryonic Antigen (CEA) |
|
Definition
Use – monitoring for persistent , recurrent, or metastatic colon cancer
Elevated in smokers |
|
|
Term
| HUMAN CHORIONIC GONADOTROPIN (beta-HCG |
|
Definition
Diagnosis, monitoring and prognosis of gestational trophoblastic tumors (non seminomatous testicular cancer)
Diagnoses pregnancy, pre-natal screening for Down syndrome |
|
|
Term
|
Definition
| Use – Medullary thyroid carcinoma |
|
|
Term
|
Definition
Monitoring ovarian carcinoma, screening for familial ovarian carcinoma
Increased in all peritoneal stimulating conditions including endometriosis, hepatitis, ovarian cysts and GI disease |
|
|
Term
|
Definition
| associated with pancreatic and colorectal CA |
|
|
Term
|
Definition
monitoring of breast cancer
controversial |
|
|
Term
|
Definition
| screening for hepatoma, germ cell tumor prognosis and monitoring |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| – pancreatic and colorectal cancer marker, |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Increased in CLL, multiple myeloma, b-cell disorders, lung cancer, hepatoma and breast cancer |
|
|
Term
|
Definition
| CNS dysgerminomas, meningeal carcinomas |
|
|
Term
| carcinoembryonic Ag (CEA) in CSF |
|
Definition
| Meningeal carcinomatosis, brain metastasis from adenocarcinoma (esp squamous cell carcinomas) |
|
|
Term
| beta-glucoronidase in CSF |
|
Definition
| Meningeal carcinomatosis, brain metastasis from adenocarcinoma (esp squamous cell carcinomas) |
|
|
Term
| human chorionic gonadotropin (hCG) in CSF |
|
Definition
| CNS dysgerminomas, meningeal carinomatosis |
|
|
Term
| lysozyme (muramidase) in CSF |
|
Definition
| CNS tumors, especially myoclonal and monocytic leukemias |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| pancreatic and colon CA markers |
|
Definition
|
|
