Giotto di Bondone, Interior and Lamentation Fresco of the Arena Chapel (Cappella Scrovegni), fresco, Padua, 1305-1306. (Middle Age Period) naturalistic

Duccio di Buoninsegna, Maestà altarpiece, Siena cathedral, Siena, 1308-1311, tempera o/wood (Middle Age period) Italo-Byzantine Art

Simone Martini and Lippo Memmi (?), Annunciation, 1333, tempera o/wood (middle age period)

Ambrogio Lorenzetti, Peaceful City, from Effects of Good Government in the City and in the Country, Sala della Pace, Palazzo, Pubblicco, Siena, 1338-1339, fresco (middle ages, located in Siena's town hall)

Gentile da Fabriano, Adoration of the Magi, Altarpiece for Santa Trinità, Florence, 1423, tempera o/wood (Renaissance Period)

Massacio, Tribute Money, Brancacci Chapel, Santa Maria del  Carmine, Florence, c. 1427, fresco (Renaissance Period)

Massacio, Expulsion of Adam and Eve from Eden, Brancacci Chapel, Santa Maria del Carmine, Florence, c. 1425, fresco (Renaissance Period)

Massacio, Holy Trinity, Santa Maria Novella, Florence, c. 1428, fresco (Renaissance Period)

Fra Angelico, Annunciation, San Marco Monastery, Florence, c. 1440-1445, fresco (Renaissance Period)

Andrea del Castagno, Last Supper, Refectory of the Monastery of Sant’Apollonia, Florence, 1447, fresco (Renaissance Period)

Perugino, Christ Delivering the Keys of the Kingdom to Saint Peter, Sistine Chapel, Vatican, Rome, 1481-1483, fresco (Renaissance Period) 

Andrea Mantegna, Camera degli Sposi (Room for the Newlyweds), Palazzo Ducale, Mantua, 1474, fresco (Renaissance Period) Extreme Illusionism

Andrea Mantegna, Dead Christ, c. 1501, Tempera o/canvas (foreshortening)

Lorenzo Ghiberti, Sacrifice of Isaac, Competition Panel for East Doors, Baptistery of Florence Cathedral, Florence, 1401-1402, gilded bronze relief

Nanni di Banco, Four Crowned Saints, Or San Michele, Florence, c. 1408-1414, marble Donatello, David, late 1420s-late 1450s, bronze

Andrea del Verocchio, David, c. 1465-1470, bronze

Fillippo Brunelleschi, Dome of Florence Cathedral, South View, Florence, 1420-1436

Michelozzo di Bartolommeo, Palazzo Medici-Riccardi, Florence, begun 1445

Jan Van Eyck, Ghent Altarpiece, Saint Bavo Cathedral, Ghent, completed 1432, oil o/wood

Jan Van Eyck, Man in a Red Turban, 1433, oil o/wood

Jan van Eyck, Giovanni Arnolfini and His Bride, oil o/wood, 1434

Rogier van der Weyden, Deposition, for Church of Notre-Dame-hors-les-Murs, Louvain (Belgium), c. 1435, oil o/wood

Hugo van der Goes, Portinari Altarpiece (open), Church of San’Egidio, Florence, c. 1476, tempera and oil o/wood

Robert Campin (Master of Flémalle), Mérode Altarpiece, c. 1425-1428, oil o/wood

Hieronymous Bosch, Garden of Earthly Delights, 1505-1510, oil o/wood