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        | The continued use of a substance/drug despite known detrimental or harmful effects is best defined as: |  
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        | The presentation of aberrant drug taking behaviors in a patient with pain which ceases upon increasing the use of the drug is defined as: |  
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        | The gradual decrease in the analgesic effectiveness of a drug is defined as: |  
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        Term 
        
        | Upon the repetitive firing and depolarization of primary afferent 1st order neurons, the failure of the cells to completely repolarize for physiological reasons is defined as: |  
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        Definition 
        
        | The process is which the nervous system changes inappropriately due to ongoing, long-term noxious stimulus |  
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        Term 
        
        | As a result of direct damage or demyelination of a nerve, this results: |  
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        | Refers to afferent nerves being "cut off" from communication further up the nervous system |  
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        Definition 
        
        | A Heightened response to a normally painful stimuli |  
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        Definition 
        
        Perceiving a normally non-noxious, or painful, stimuli as a noxious or painfaul stimuli 
Ex: pts with diabetic neuropathy have pain with putting on a dress, socks, shoes, bed sheets, etc.  |  
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