Shared Flashcard Set

Details

PAD
Chesson PAD
12
Pharmacology
Graduate
04/07/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
What are risk factors for PAD?
Definition
Major: Smoking, HTN, lipids, DM2
Minor: CAD, age, homocysteine, GFR<60ml/min
Term
What are the two most common signs of PAD?
Definition
- Intermittent Claudication - primary indicator. During exercise, resolves with rest.
- Pain at rest in lower extremities later in the disease due to ischemia.
Term
What presents on a physical exam for PAD?
Definition
- Decreased lower pulse
- Cool, Shiny, hairless skin
- sores, ulcers, or thickened toenails
Term
How is a PAD firmly diagnosed?
Definition
Ankle-brachial index
1 - 1.4 = normal
0.91 - 0.99 = borderlone
0.71 - 0.90 = mild
0.41 - 0.70 = moderate
0.00 - 0.40 = severe
Term
Which patients may have non-compressible arteries?
Definition
- Diabetic, elderly, and dialysis patients
Term
What are the goals of treatment of PAD?
Definition
- increase maximum walking distance and duration of pain free walking
- improve quality of life
- control risk factors
Term
What risk factor goals exist for PAD patients?
Definition
<140/90 BP
Lipids <100
A1C < 7%
Quit smoking
Term
What is the first line of treatment for PAD?
Definition
Aspirin 81-325 mg po daily
Use Plavix in patients who cannot tolerate ASA
Term
What other drug therapy options are there for PAD?
Definition
- Cilostazol 100 mg BID for nonsurgical patients who have failed lifestyle modifications. Avoid in CHF.
- Pentoxifylline 400 TID - last line
Term
What kind of exercise program is recommended in PAD?
Definition
Minimum of 30 minutes supervised training 3x/week x12 weeks to produce symptoms of IC within 5 minutes and then allow to resolve.
Term
What is Raynaud's Phenomenon?
Definition
A vascular response to cold and stress, usually in women. Secondary is autoimmune.
Primary is in young women, no pain.
Term
Where does Raynaud's appear?
How is it treated?
Definition
in the hands. White --> Blue --> Red
Must have history for at least 2 years
Avoid cold temperatures and stress, stop smoking.
Tx with Nifedipine or Amlodipine, sometimes topical NTG
Supporting users have an ad free experience!