Term
Oddball Paradigm:
-Uses at least ___ stimuli
-One stimuli presented ____
-Another stimuli presented ___ (aka the odball stimulus) |
|
Definition
| two; frequently; infrequently |
|
|
Term
Standard:
-The ___ signal in the stimulus paradigm
-___
-Accounting for about ___% of stimuli presented |
|
Definition
| frequent; Predictable; 80 |
|
|
Term
Target:
-The ___, unpredictable and rare stimulus
-Sometimes referred to as ___ stimuli
-Presented in a ___-___ fashion
-Account for about ___% of stimuli presented |
|
Definition
| infrequent; deviant; pseudo-random; 20 |
|
|
Term
Novel:
-Novel stimuli are highly ___ and usually presented along with target and standard stimuli in a ___-stimulus paradigm
-Even without subject ___ to the novel stimuli, novel stimuli generate a P300 response |
|
Definition
| deviant; three; attention |
|
|
Term
| The P300 response elicited by the highly deviant stimuli |
|
Definition
|
|
Term
| Shorter latency P3 wave that is evoked independent of attention to the rare stimuli; waveform changes with attention |
|
Definition
|
|
Term
| Conventional wave in the P300 response |
|
Definition
|
|
Term
| P3b appears at about ___ msec post presentation of rare stimulis in the tradition oddball paradigm (attention to the rare stimulus) |
|
Definition
|
|
Term
| List the 5 most prominent cortical structures from which the response is generated |
|
Definition
-Area 8=Superior frontal gyrus of frontal lobe
-Area 10=Inferior frontal gyrus in frontal lobe
-Area 32=Cingulate gyrus of limbic lobe
-Area 39=Middle temporal gyrus in temporal lobe and angular gyrus of parietal lobe |
|
|
Term
| List 4 functional areas which are associated with the response |
|
Definition
| Working memory, context updating, target recognition, and novelty/salience detection |
|
|
Term
| List 8 potential clinical uses for P300 |
|
Definition
-Schizophrenia
-Bipolar disorder
-Obsessive Compulsive disorder
-Major depressive disorder
-Anxious-depressive tendencies
-Attention deficit hyperactivity disorder
-Parkinson’s disease
-Addiction |
|
|
Term
A study on Schizophrenia showed:
-Standard late ___ frequency power significantly discriminated schizophrenia from healthy population
-Reduced amplitude ___ component
-___ latency P300 |
|
Definition
|
|
Term
Bipolar Disorder study showed:
-Reduced ___ amplitude and ___ latency |
|
Definition
|
|
Term
OCD Study:
-No ___ difference of P300 amplitude
-Latency significantly ___ in frontal leads correlating well with neuro-imaging and neuropsychological studies that implicated the frontal lobe involvement in OCD |
|
Definition
|
|
Term
Major Depressive Disorder Study Showed:
-___ (novelty P3) significantly affected
-“indicative of a deficit in orienting of ___ and evaluation of novel ___ sounds” |
|
Definition
| P3a; attention; environmental |
|
|
Term
Anxious-Depressive Tendencies Study:
-Only the ___ P300 showed a difference between groups
-___ ___ in response time or P300 latencies in two groups when detecting deviant stimuli |
|
Definition
|
|
Term
ADHD Study:
-___ in latency of visual P300, but no significant difference in ___ P300 |
|
Definition
|
|
Term
Addiction Study:
-Possible ___ ___ to track changes in subjective MA craving among abstinent MA dependent patients |
|
Definition
|
|
