| Term 
 | Definition 
 
        | Produced from cell metabolism.  About 65% carried inside RBC's.  About 30% combines with hemoglobin.  About 5% transported in solution in plasma. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   As cells consume O² partial pressure in tissue drops, causing O² at arterial end of the capillary to diffuse into cells.  When cells consume more O², stress/excerise, the pressure gradient & diffuse are enhanced.  |  | 
        |  | 
        
        | Term 
 
        |   Systemtic Diffusion (CO²) |  | Definition 
 
        |   CO² from metabolic processes accumulates in tissues & diffuses into capillaries where partial pressure is lower. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Healthy bodies are driven to breathe by high CO² levels not low O² levels. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | A chemosensitive center in the medulla oblongata is highly responsive to high CO² in the blood.  This center influences other respiratory centers & increases activity of respirations, rate & depth.  Also nueral receptors outside the CNS in the carotid bodies & aortic bodies above & below the aortic arch are sensitive to a decrease in O². |  | 
        |  | 
        
        | Term 
 
        |   Factors causing O² to be main drive to breathe   |  | Definition 
 
        | Some chronic lung ailments such as emphysema, cause low O² to be the main drive to breathe.  Here chronically high CO² "desensities" the chemoreceptors.  Sometimes called the hypoxic drive.  So increasing the O² concentration depresses breathing.  O² must be administered with caution. |  | 
        |  |