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OTC
lectures 1 and 2
67
Other
Graduate
04/12/2010

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Cards

Term
What are the top two recommendation from pharmacists in vitamins or minerals?
Definition
Ca = 1,200,000
multivitamin 950,000
Term
What are the top two recommendation from pharmacists in herbals?
Definition
omega 3's 678,000
fiber 565,000
Term
what is the RDA?
Definition
recommended daily allowence
-avg daily dietary intake that will meet 97-87% of healthy people
-renewed every 10 years
Term
what is DRI
Definition
dietary reference intakes
-RDA/AI and Tul/ul +EAR
Term
what is AI
Definition
average intake
-made when the RDA cannot be eastablished, based on healthy persons intake
Term
what is Tul/ul?
Definition
tolerable upper intake levels
-maximum nutrient daily nutrients that pose no adverse effects or toxicity
Term
what is the definition for a vitamin?
Definition
an organic substance that is essential for maintaing metabolism that is not made in the body
Term
people with allergies that cannot eat certain foods may have an ___
Definition
inadequate intake
Term
what is intestinal sprew?
Definition
distrubance of absorption
-malabsorption disease
-IBS, diarrhea, hyperthyroidism
Term
what is megavitamin therapy or orthomolecular psychology?
Definition
gave massive doses of vitamins to treat disease - failed, no science or cure
Term
What are the 2 important laws set in 2007?
Definition
GMP - good manufacturing practices
AERs adverse event reporting
-responsible to report adverse events
Term
what is vitamin B1?
Definition
thiamine or thiamin (T HCL)
Term
every vitamin for the most part has ___ status
Definition
cofactor
Term
vitamin B1 deficieny is called ___
Definition
Beriberi disease
Term
lacking vitamin B1 would see
Definition
-higher blood pressure
-if in childhood = may not grow
-memory loss
*thiamine does not improve memory loss
Term
Thiamine toxicities are extensive, and they are ___
Definition
*hypersensitivity
*nervousness and weakness
*convulsion and trembling
-increased enzyme turnover
*HA, neuromuscular paralysis
*arrhythmias, HTN
*shock, dilation, edema
Term
there is study that high vitamin B1 can help reverse ___ disease in ___
Definition
renal disease in diabetics
Term
what is vitamin B2
Definition
riboflavin
Term
B2 has a natural color, and makes urine ___
Definition
bright yellow or amber-ish
Term
common sources of B1 is ___/___/___
Definition
sunflower seeds/beans/corn
Term
we absorb B2 as FMN, which is ___
Definition
riboflavin phosphate
-so you can absorb in skin if its in a shampoo etc
Term
With a deficiency in B2, you will start to see ___
Definition
seborrhea dermatitis
-whole body dandruff
Term
what are the 3 types of dry flakey skin associated with B2 deficiency?
Definition
Stomatitis - of the mouth
Glossitis - of the tongue
Cheilosis - cracking of lips
Term
It is very hard to have a life threatening deficiency in ___
Definition
riboflavin
Term
many hormones are activated/helped by B2, what are 2?
Definition
thyroxine and insulin
Term
B2 toxicity, it will inhibit ___ in neoplastic cells, so this is not necessarily good to take in ___
Definition
methotrexate
cancer patients
-best not to avoid in diets though
Term
What is vitamin B3
Definition
nicotinic acid
nicitinamide
niacin
*in NAD/NADPH etc
Term
what is the only vitamin that can be supplemented by non-vitamin taking?
Definition
B3 - niacin
*tryptophan turns into B3
Term
what is the B3 deficiency?
Definition
Pellagra
-tongue erythema, a darkening of this
Term
deficiency in B3 is from not having enough
Definition
protein in the diet
Term
Niacin toxicity is usually found at ___ grams
Definition
1-4
Term
There are many niacin toxicities, and they are
Definition
FFH - flushing, fainting, hypoTN
rash -pruritus
HB, NVD - avoid in IBS
ulcer
liver -jaundice
hyperglycemia, atrial fib
pigmented hyperkeratosis
-found in orthomolecular psychiatry
Term
A myth about B3 is that excessive amounts of this will ___
Definition
mask drug testing
Term
What is vitamin B7 (2 names)
Definition
also known as vitamin H AND biotin
Term
Biotin is produced from ___
Definition
the flora in the GIT
-so its impossible to have a deficiency
Term
people having a deficiency problem in B7 are on ___
Definition
total parenteral nutrition
Term
A deficiency in B7, you would normally see ___
(important fact on the back)
Definition
loss of hair on the face and body
*shampoos market biotin = false
*no B vitamins are absorbed through the skin
Term
The bacteria responsible for making biotin in the gut are called ___
Definition
Strept Avidin
Term
What is vitamin B6?
Definition
pyridoxine -base
pyridoxal -aldehyde
pyridoxamine -amine group
Term
B6 is highly found in ___
Definition
meats, cereals, nuts
Term
B6 is involved in the maintenance in the adrenal cortex hormones such as ___
Definition
FSH/LH/cortical/testosterone
Term
B6 helps protect against ___ and is this vitamin can single-ly be termed the ___ vitamin
Definition
dental carries
stress vitamin
Term
There are extensive ___ associated with B6, in which is will reduce ___/___ and keep ___
Definition
myths/PMS/hangovers/mosquitoes away
Term
One woman took excessive amounts of B6, 5 grams/day, and she had many problems such as ___
Definition
loss of touch, no limb reflexes, needed 2 canes to walk
Term
B6 may decrease ___ risk but don't push this, and it can have a minor help with ___
Definition
colorectal/carpal tunnel
Term
What is vitamin B5?
Definition
Pantothenic acid
Term
B5 is in everything we eat just about, and has a major part in ___
Definition
acetylCoA
Term
There is not to much know about vitamin B5, not scientifically proven to heal ___. Also, there are no ___
Definition
broken skin
deficiencies known
Term
Vitamin C is an ___, and it can convert ___ to ___ for collagen
Definition
antioxidant
proline to hydroxyproline
Term
Vitamin C deficiency is known as ___
Definition
scurvy
Term
Scurvy symptoms are many...
Definition
teeth fall out
bruises/scrapes do not heal
internal/external ulcers form
no iron absorption
poor WBCs and lack of RBC function
Term
The major metabolite of vitamin C is ___, which this can form ___
Definition
oxalic acid (COOH-Ca-HOOC)
Raphides -sharp crystal-like stones
Term
It is more common to die from ___ than lacking vitamin C in malnutrition
Definition
infection
Term
Three are three types of people that will require higher than normal amounts of vitamin C
Definition
hyperthyroidism
pregnant females
Cancer patients
Term
There are many toxicities associated with vitamin C
Definition
diarrhea - vitamin C squirts
cysteine/oxalate stones in urinary tract
rebound scurvy in neonates
Decreases prothrombin time (clotting)
megablastic anemia
Term
mixing in vitamin ___ with vitamin C will cause vitamin C to degrade, but not seen in the body
Definition
vitamin B6
Term
Taking vitamin C at the ___ of a cold can shorten the severity and duration, so its better in prophylaxis
Definition
12 hour onset
*decreased by one day
Term
Being predisposed to ___ would be a poor patient to recommend vitamin C to.
Definition
stones
Term
It is recommended to take ___ of vitamin C a day if you are not eating fresh fruits/tomatoes
Definition
one gram
Term
Taking one gram of vitamin C is similar to having ___ before bed
Definition
a cup of coffee
Term
People with strokes should not increase
Definition
vitamin C intake
Term
What is vitamin B9?
Definition
folic acid
folate
Term
Folic acid may reduce ___ in women and protect women against ___ (but a low does B12 is better)
Definition
HTN
cervical cancer
Term
A combination of ___ and ___ can help fight against colorectal cancer
Definition
vitamin B6 and folate
Term
B9 may* help reduce ___ and it will give* healthier ___
Definition
Alzheimer's
sperm
Term
Main problem in lacking folic acid is having
Definition
RBC problems
Term
What is EAR?
Definition
estimated average requirement
-amount of nutrients to meet 50% of healthy people
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