Term
| compared to "young, normal" adults of same sex |
|
Definition
|
|
Term
| compared to expected normals of patient's age and sex |
|
Definition
|
|
Term
| antacid/calcium supplement; 40% elemental iron |
|
Definition
|
|
Term
|
Definition
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|
Term
| binds to bone hydroxyapatite and inhibits osteoclast-mediated bone resorption |
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Definition
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|
Term
| acts by reducing bone resorption and increasing bone mineral density |
|
Definition
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|
Term
| reduces the number of osteoclast and prevents resorptive activity of the bone resulting in a reduced bone turnover rate. It also temporarily improves bone formation by increasing osteoblastic activity |
|
Definition
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|
Term
| stimulates new bone formation on trabecular and cortical bone surfaces by preferential stimulation of osteoblastic activity over osteoclastic activity |
|
Definition
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|
Term
| receptor activator of nuclear factor kappa-B ligand (RANKL) inhibitor. Binding to the transmembrane or soluble protein RANKL inhibits the formation, function, and survival of osteoclasts resulting in decreased bone resorption and increased bone mass and strength |
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| may be sacrificed to maintain target intra and extracellular concentrations (in elderly) |
|
|
Term
| increased risk of osteoporosis |
|
Definition
| on glucocorticoids or have decreased gastric acid production |
|
|
Term
| required to ensure adequate calcium and phosphorus absorption by small bowel |
|
Definition
|
|
Term
| decreases vitamin D absorption |
|
Definition
| anticonvulsants/glucocorticoids |
|
|
Term
| alendronate, ibandronate, risedronate, zoledronic acid |
|
Definition
|
|
Term
|
Definition
| calcium and vitamin d levels should be corrected; prevents BMD loss/potentially increase BMD, decrease ris kfo vertebral and nonvertebral fractures; can cause GI upset and long-term safety is unknown |
|
|
Term
| monoclonal antibody against RANKL |
|
Definition
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|
Term
|
Definition
| diarrhea, N/V; musculoskeletal pain; fatigue; skin infections; hypocalcemia must be corrected prior to starting therapy; ONJ has been reported |
|
|
Term
|
Definition
|
|
Term
| Raloxifene Contraindications |
|
Definition
| nursing mothers; pregnancy; VTE |
|
|
Term
| inhibits osteoclast activity, stimulates osteoblast activity |
|
Definition
|
|
Term
| acts on osteoclasts, resulting in decreased resorption and bone turnover |
|
Definition
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