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Osteoarthritis
Therapy Final
22
Pharmacology
Professional
12/08/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
osteroarthritis definition
Definition
wearing down of joints, especially cartilage; does not involve the immune system so you don't need to give something for inflammation
Term
topical NSAID
Definition
Voltaren gel
Term
salicylate topical
Definition
aspercream
Term
methanol/ salicylate
Definition
Bengay, Icy-Hot
Term
capsacin
Definition
inhibits substance P involved in pain signaling, does not block pathway, might take few weeks to see improvement
Term
Voltaren gel
Definition
recommended over oral NSAIDs with reduced risk for side effects, epensive
Term
Salonpas
Definition
salicylate
Term
lidoderm patch; lidocane topical
Definition
might be useful for specific pain (ie. back pain); expensive and might not be covered
Term
extra strength tylenol
Definition
500mg X 6 tabs/day = 3000mg limit
Term
regular strength tylenol
Definition
325 X 10 tabs/day = 3250mg limit
Term
extended release tylenol
Definition
650mg X 6 tabs/day = 3900mg limit
Term
tylenol limit
Definition
4000mg
Term
NSAIDs
Definition
inhibits Cox1 (housekeeping) and Cox2 (inflammation)
Term
Cox1
Definition
housekeeping; involved in mucus layer production in stomach, ulceration occurs from systemic effect
Term
Cox2
Definition
inhibition of prostaglandins periferally; decreasing inflammation
Term
Salsalate, choline-magnesium salicylates
Definition
non-acetylated salicylates; weaker than some NSAIDs but better SE profile
Term
glucosamine, chondroitin
Definition
used to help re-build cartilage; takes time (4-6wks)
Term
chondroitin SE
Definition
similar to heparin, may increase risk of bleeding
Term
glucosamine SE
Definition
may increase glucose in blood, debated
Term
opioid use
Definition
for severe cases and can acquire tolerance, causes CONSTIPATION
Term
sodium Haluronate
Definition
used to lubricate the joint, used in knee as injection (medical device rather than drug)
Term
hydrocortisone shots
Definition
may be useful for acute pain, helpful for patients with local inflammation and joint effusion; no more than every three months
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