Shared Flashcard Set

Details

Oral Pathology
Chp.1, 2, 3, 5, 6, 8
244
Pathology
Undergraduate 3
02/24/2010

Additional Pathology Flashcards

 


 

Cards

Term
Ankyloglossia
Definition
extensive adhesion of the tongue to the floor of the mouth or lingual aspect of the ant. portion of the mandible
Term
Ankylosed teeth
Definition
teeth that are fused to the alveolar bone; a condition esp. common with retained deciduous teeth.
Term
Anodontia
Definition
congential lack of teeth
Term
anomaly
Definition
marked deviation from normal, esp. as a result of congenital or hereditary defects.
Term
Concrescence
Definition
In dentistry a condition in which two adjacent teeth become united by cementum
Term
congenital
Definition
present at time of birth
Term
dens in dente
Definition
"a tooth within a tooth" a developemental anomaly that results when the enamel organ invaginates into the crown of a tooth before mineralization
Term
dilaceration
Definition
an abnormal bend or curve, as in the root of a tooth
Term
fusion
Definition
union of two adjacent tooth germs
Term
gemination
Definition
"twinning"; a single tooth germ attempts to divide, resulting in the incomplete formation of two teeth; the tooth usually has a single root and root canal
Term
hypodontia
Definition
partial anodontia; the lack of one or more teeth
Term
impacted teeth
Definition
teeth that cannot erupt into the oral cavity because of a physical obstruction
Term
macrodontia
Definition
abnormally large teeth
Term
microdontia
Definition
abnormally small teeth
Term
multilocular
Definition
a radiographic appearance in which many circular radiolucencies exist; these can appear "soap bubble" or "honeycomb" like
Term
nodule
Definition
a small solid mass that can be detected through touch
Term
predilection
Definition
a disposition in favor of something; preference
Term
proliferation
Definition
the multiplication of cells
Term
stomodeum
Definition
the embryonic invagination that becomes the oral cavity
Term
supernumerary
Definition
in excess of the normal or regular number, as in teeth
Term
acantholysis
Definition
dissolution of the intercellular bridges of the prickle cell layer of the epithelium
Term
acquired immune response
Definition
a response of the body to injury that has memory of past exposure to a foreign substance and responds more quickly to a foreign substance when encountered a 2nd time
Term
allergy
Definition
a hypersensitive state acquired through exposure to a particular allergen; reexposure to the same allergen elicits an exaggerated reation
Term
anaphylaxis
Definition
a sever type of hypersensitivity or allergic reaction in which the exaggerated immunologic reaction results from the release of vasoactive substances such as histamine; the reaction occures on the reexposure to a foreign protein or other substance after sensitization
Term
antibody
Definition
a protein molecule, aslo called an immunoglobulin, which is produced by plasma cells and reacts with a specific antigen
Term
antigen
Definition
any substance able to indue a specific immune response
Term
autoantibody
Definition
an antibody that reacts against an antigenic constituent of the person's own tissues
Term
autoimmune disease
Definition
a disease characterized by tissue injury caused by a humoral or cell-mediated immune response against constituents of teh body's own tissues
Term
B lymphocyte (b cells)
Definition
a lymphocyte that matures without passing through the thymus; the b cell can later develop into a plasma cell that produces antibodies
Term
cell-mediated immunity
Definition
immunity in which the predominant role is played by T lymphocytes
Term
cytokine
Definition
cell product produced by the cells involved in the immune response
Term
Humoral Immunity
Definition
immunity in which B lymphocytes and anitbodies play the predominant role
Term
hypersensitivity
Definition
a state of altered reactivity in which the body reacts to a foreign agent with an exaggerated immune response
Term
immune complex
Definition
a combination of antibody and antigen
Term
immunodeficiency
Definition
a deficiency of the immune response resulting from hypoactivity or decreased numbers of lymphoid cells
Term
immunoglobulin
Definition
a protein, also called an antibody, synthesized by plasma cells in response to a specific antigen
Term
LE cell
Definition
a cell that is characteristic of lupus erythematosus and other autoimmune diseases; it is a mature neutraphil that has phagocytized a spherical inclusion derived from another neutrophil
Term
lymphoid tissue
Definition
tissue composed of lymphocytes supported by a meshwork of connective tissue
Term
macrophage
Definition
a large tissue-bound mononuclear phagocyte derived from monocytes circulating in blood; macrophages become mobile when stimulated by inflammation and interact with lymphocytes in an immune response
Term
mucositis
Definition
mucosal inflammation
Term
Natural Killer Cell
Definition
a lymphocyte that is part of the body's initial innate immunity, which by unknown mechanisms is able to directly destroy cells recognized as foreign.
Term
Nikolsky's sign
Definition
in some bullous diseases such as pemphigus vulgaris and bullous pemphigus the superficial epithelium separates easily from the basal layer on exertion of firm, sliding manual pressure
Term
Rheumatoid factor
Definition
a protein, immunoglobulin M (IgM), found in serum and detectable on laboratory tests; it is associated with rheumatoid arthritis and other autoimmune diseases
Term
T lymphocyte
Definition
a lymphocyte that matures in the thymus before migrating to tissues; responsible for cell mediated immunity and may modulate the humoral immune response
Term
Thymus
Definition
a lymphoid organ located high in the chest, which is large in an infant and gradually shrinks in size.
Term
Xerophthalmia
Definition
abnormal dryness of the eyes
Term
alleles
Definition
genes that are located at the same level or locus in the two chromosomes of a pair and that determine the same functions or characteristics
Term
amino acid
Definition
organic compound containing the amino group NH2; main component of proteins
Term
autosomes
Definition
nonsex chromosomes, identical for men and women
Term
Barr body
Definition
condensed chromatin of the inactivated X chromosome, which is found at the periphery of the nucleus of cells in women
Term
carrier
Definition
in genetics a heterozygous individual who is clinically normal but who can transmit a recessive trait or characteristic
Term
centromere
Definition
constricted portion of the chromosome that divides the short arms from the long arms
Term
chromatid
Definition
either two vertical halves of a chromosome that are joined at the centromere
Term
chromatin
Definition
general term referring to the material (DNA) that forms the chromosomes
Term
codon
Definition
vertical sequence of 3 bases in DNA that codes for an amino acid
Term
consanguinity
Definition
blood relationship; describes a mating or marriage between close relatives
Term
deoxyribonucleic acid
Definition
substance composed of double chain of polynucleotides; both chains coiled around a central acid form a double helix; it is the basic genetic code or template for amino acid formation
Term
diploid
Definition
having two sets of chromosomes; the normal constitution of somatic cells.
Term
dominant
Definition
a trait that is manifested when it is carried by only one of a pair of homologous chromosomes
Term
expressivity
Definition
degree of clinical manifestation of a trait
Term
facies
Definition
appearance of the face
Term
gamete
Definition
spermatozoon or ovum
Term
genetic heterogeneity
Definition
having more than one inheritance pattern
Term
haploid
Definition
cell with a single set of chromosomes; a gamete is an example
Term
heterozygote
Definition
individual with 2 different genes at the allele loci
Term
homozygote
Definition
individual having identical genes at the allele loci
Term
hypohidrosis
Definition
abnormally diminished secretion of sweat
Term
hypotrichosis
Definition
presence of less than normal amount of hair
Term
karyotype
Definition
photomicrographic representation of a person's chromosomal constitution arranged according tot he Denver classification
Term
locus
Definition
position occupied by a gene on a chromosome
Term
meiosis
Definition
two step cellular division of the original germ cells, which reduces the chromosomes from 4nDNA to 1nDNA
Term
metaphase
Definition
phase of cellular division in which the chromosomes are lined up evenly along the equitorial plane of the cell and in which they are most visible
Term
mitochondria
Definition
cytoplasmic organelles that have their own DNA in a circular chromosome
Term
mitochondrial DNA
Definition
unique DNA that is maternally inherited
Term
mitosis
Definition
way in which somatic cells divide so that the two daughter cells receive the same number of identical chromosomes
Term
mutation
Definition
permanent change in the arrangement of genetic material
Term
oogenesis
Definition
process of formation of female germ cells (ova)
Term
ovum
Definition
egg; mature feminine germ cell
Term
penetrance
Definition
frequency with which a heritable trait is exhibited by individuals carrying the gene or genes that determine that trait
Term
phenotype
Definition
entire physical, biochemical, and physiologic makeup of an individual; genotype is the genetic composition, and _________ is its observable appearance
Term
recessive
Definition
trait that shows clinically when a double-gene dose (homozygous) exists in autosomic chromosomes or a single-gene dose exists in males if the trait is X linked
Term
Ribonucleic Acid (RNA)
Definition
single strands of plynucleotides found in all cells; different types of RNA have different functions in the production of proteins by the cell
Term
Ribosomes
Definition
cytoplasmic organelles in which proteins are formed on the basis of the genetic code provided by RNA
Term
spermatogenesis
Definition
process of formation of spermatozoa
Term
spermatozoon
Definition
mature male germ cell
Term
syndrome
Definition
set of signs or symptoms (or both) occurring together
Term
translocation
Definition
portion of a chromosome attached to another chromosome
Term
trisomy
Definition
pair of chromosomes with an identical extra chromosome.
Term
Cyclic Neutropenia
Definition
autosomal dominant; cyclic decrease in number of circulating neutrophils; oral manifestations include severe ulceration of gingiva which can also occur on tongue and mucosa, w/ very painful with bleeding base.
Term
Papillon-Lefevre syndrome
Definition
autosomal recessive; hyperkeratosis of the palms of the hands and soles of the feet; destruction of PDL of both dentitions w/ premature loss of teeth. age 1 1/2 to 2: gingivoperiodontal inflammation & edema, bleeding, alveolar bone resportion, tooth mobility, exfoliation (in sequence in which they erupted). neutrophil chemotaxis decreased.
Term
Cherubism
Definition
ausosomal dominant; penetrance in males, incomplete penetrance in females, facial swelling age 1 1/2 - 4 yrs. displacement of eyes, Rads show "soap bubble" appearance, which are occupied by fibrous connective tissue. jaw size increases til puberty.
Term
Ellis-van Creveld syndrome
Definition
autosomal recessive; affected individuals are dwarfs. shortening of extremities, hands polydactyly on ulnar side. fusion of anterior of maxillary gingiva to upper lip from canine to canine. central incisors lacking replaced by centrally located abnormal tooth. enamel hypoplasia
Term
mandibulofacial dysostosis (Treacher Collins syndrome)
Definition
autosomal dominant; mouth appears fishlike, downward sloping commissures, ears exhibit tags, hypoplastic mandible, teeth malposed, malocclusion with open bite, high palate, cleft in 30%
Term
Osteogenesis imperfecta
Definition
autosomal-dominant; defect involves collagen, presents w/ abnormally formed bones that fracture easy, bowing of legs, oral:primary teeth more affected, crown,root,pulp smaller than normal. teeth opalescent/translucent @ eruption, abnormal dentin, enamel lost bc no adequate support.
Term
hereditary hemorrhagic telangiectasia (Osler-Rendu-Parkes Weber syndrome)
Definition
autosomal dominant; multiple capillary dilations of skin and mucous membranes. frequent nosebleeds, spiderlike lesions esp. on tip and anterior dorsum of tongue, lesions hemorrhage.
Term
Peutz-Jeghers syndrome
Definition
autosomal dominant; multiple melanotic macular pigmentations of kind and mucosa, associated with gastrointestinal polyposis. intestinal polyps mostly in small intestine; rarely malignant
Term
white sponge nevus (Cannon disease)
Definition
autosomal dominant; complete penetrance, mutation in mucosal keratin, white corrugated soft folding oral muscosa. buccal mucosa always affected. not on free gingiva
Term
hypohidrotic ectodermal dysplasia
Definition
X linked recessive trait / autosomal recessive trait. ectodermal dysplasia, hypodontia, hypotrichoisis, hypohidrosis. some patients die of hyperthermia. small conical crowns. partial lack of minor salivary glands
Term
hypophosphatasia
Definition
autosomal recessive; decrease in serum alkaline phosphatase levels which participates in calcification of bone and cementum, tissues altered. teeth exfoliated w/out evidence of disease. total lack of cementum in exfoliated teeth implies lack of PDL attatchment
Term
hypophosphatemic vit.D-resistant rickets
Definition
X linked dominant; low phosphorus serum levels. individuals are short stature, bowlegs, large pupl chambers, long pulp horns, dentin has cracks extend to DEJ, induce fracture of enamel, microexposure of pulp
Term
Gardner Syndrome
Definition
autosomal dominant; osteomas in mand & maxilla. odontomas in jawbones, teeth exhibit hypercementosis & fail to erupt. intestinal polyps, malignant @ age 30 affecting colon and rectum, develop before puberty
Term
Nevoid basal cell carcinoma syndrome ( Gorlin syndrome)
Definition
autosomal dominant; hypertelorism (increased distance between eyes), basal cell carcinomas appear all over, multiple cysts of jaws (odontogenic keratocysts), ameloblastoma arises in these cysts
Term
multiple mucosal neuromas
Definition
autosomal dominant; thick large lips, overeverted upper eyelids, mucosal neuromas on lips and ant. dorsal of tongue. also on buccal mucosa. look like multiple mobile firm lumps.
Term
medullary carcinoma of the thyroid gland
Definition
dev. in 2nd decade of life, seen in multiple mucosal neuroma syndrome, 20% of patients die from metastatic lesions. produces calcitonin
Term
neurofibromatosis of von Recklinghausen
Definition
autosomal dominant; disorder of neural crest origin. multiple neurofibromas appear as papules. oral: single or multiple occur anywhere in mouth, mostly lat. of tongue. cafe au lait pigmentation
Term
Ameleogenesis imperfecta TYPE 1, hypoplastic type
Definition
type of ameleogenesis imperfecta, toothe enamel does not develop to normal thickness bc failure of ameloblasts to lay enamel matrix properly
Term
Ameleogenesis imperfecta TYPE 2, hypocalcified
Definition
type of Ameleogenesis imperfecta, can be autosomal dominant or recessive, enamel of normal thickness that is poorly calcified. on rads, moth eaten appearance, less radiopaque then dentin.
Term
Ameleogenesis imperfecta TYPE 3, hypomaturation
Definition
type of Ameleogenesis imperfecta, "snow capped teeth",enamel mottled appearance but normal thickness. composed of large amounts of enamel matrix, enamel softer than normal, defect in enamel rod sheath
Term
Ameleogenesis imperfecta TYPE 4, hypoplastic-hypomaturation
Definition
type of Ameleogenesis imperfecta associated with taurodontic teeth. thin enamel, pitted, large pulp chambers.
Term
dentinogenesis imperfecta
Definition
defect in odontoblasts which lay down abnormal matrix then degenerate. dentin very soft, chipping of enamel, radiographically no pulp chambers or root canals are seen
Term
dentin dysplasia
Definition
autosomal dominant; can be radicular or coronal, radicular:normal crowns, abnormal roots, disturbance in hertwig's epithelial root sheath. coronal: primary teeth mostly, lack of pulp chambers, small root canals.
Term
trisomy 21
Definition
down syndrome, result of nondisjunction, associated with late maternal age, hypodontia, abnormally shaped teeth, perio in 90%
Term
trisomy 13
Definition
disorder, multiple abnormatlities in various organs, 70% infants die in first 7 months. bilateral cleft lip and palate, microphthalmia or anophthalmia,polydactyly.
Term
Turner syndrome
Definition
syndrome affecting females. only 1 X chromosome present instead of 2. nondisjunction of X in paternal gamete. webbing of neck, edema of hands and feet, lack of Barr bodies
Term
Klinefelter Syndrome
Definition
syndrome affecting males, ovum carrying 2 X's fertilized by sperm with Y. presence of one Barr body. karyotype can be XXXY/XXXXY
Term
Cri du chat (cat cry)
Definition
syndrome caused by deletion. catlike cry at birth, mentally retarded
Term
wolf-hirschhorn syndrome
Definition
syndrome caused by deletion, cleft palate and intelligence quotients less than 30
Term
lyon hypothesis
Definition
X chromosome in the female is genetically canceled, variation in classic hemophilia is an example, female has normal and abnormal X, cancellation is random
Term
dentigerous cyst (follicular cyst)
Definition
around crown of unerupted or developing tooth *mostly mand. 3rd molars and man. canines.
Term
eruption cyst
Definition
cyst in soft tissue, around crown of erupting tooth. *mand. 1st molars and incisors
Term
primordial cyst
Definition
cyst develops in place of tooth, originates from remnants or degenerations of enamel organ. *luman lined by strat. squamous epithelium.
Term
odontogenic keratocyst (OKC)
Definition
cyst, frequent recurrence, lumen lined by epithelium 8-10 cell layers thick. surfaced by parakeratin* usually extend beyond borders on rad. between trabeculae.
Term
calcifying odontogenic cyst (COC)
Definition
cyst. lined by odontogenic epithelium, resembles odontogenic tumor. associated with ghost cells
Term
lateral periodontal cyst
Definition
cyst, named for location, lateral to root, *mostly mand. canine & PM, thin strat. squamous epi.
Term
odontogenic
Definition
related to tooth developement, describes cysts
Term
nasopalatine canal cyst
Definition
cyst, mostly adults 40-60, males, small bulge between roots of max. centrals, radiographically heart shaped.
Term
globulomaxillary cyst
Definition
cyst roots of lateral incisors and canines, pear shaped
Term
dermoid cyst
Definition
cyst. present at birth, usually floor of mouth involved, doughlike when palpated, may cause displacement of tongue
Term
static bone cyst, simple bone cyst, aneurysmal bone cyst
Definition
what are the three kinds of pseudocysts
Term
aneurysmal bone cyst
Definition
pseudocyst, blood filled space, surrounded by multinucleated giant cells and fibrous connective tissue. *soap bubble appearance*
Term
dens evaginatus
Definition
accessory enamel cusp on occlusal surface, tuberculated premolars, proliferation and outpouching of enamel epithelium during development
Term
regional odontodysplasia
Definition
"ghost teeth" reduction in radiodensity, thin enamel & dentin, large pulp chambers, typically nonfunctional and malformed
Term
impacted teeth
Definition
teeth that dont erupt due to physical obstruction
Term
embedded teeth
Definition
teeth that dont erupt due to lack of eruptive force
Term
enamel hypoplasia
Definition
incomplete/defective formation of enamel. due to disturbance or damage to ameloblasts during enamel matrix formation.
Term
turner tooth
Definition
enamel hypoplasia, type caused by local infection, nickname for teeth is:
Term
mulberry molars, hutchinson incisors
Definition
enamel hypoplasia, type caused by syphilis, teeth called:
Term
epidermal cyst
Definition
nodule on face/neck lined by keratinizing tissue that resembles skin, *lumen filled with keratin scales, thought to originate from hair follicles
Term
passive natural
Definition
type of immunity when your mother passes antibodies through placenta to you
Term
active natural
Definition
type of immunity when you get sick and make your own antibodies
Term
passive aquired
Definition
when you dont make your own antibodies and get injected with someone elses
Term
active aquired
Definition
type of immunity from a vaccine when you are injected with antigens and make your own antibodies
Term
innate immunity
Definition
immunity with no memory
Term
IgA
Definition
antibodies, involved in blood and secretions. defense againsts microorganisms in body fluids
Term
IgD
Definition
antibody that activates B lymphocytes
Term
IgE
Definition
antibody involved in hypersensitivity reactions. binds to mast cells, cause release of biochemical mediators (histamine)
Term
IgG
Definition
antibody in blood serum & can pass placenta. form first passive immunity for newborn
Term
IgM
Definition
antibody involved in early immune responses bc involvement with IgD & B lymphocyte activation
Term
Type 1 Hypersensitivity
Definition
which type of hypersensitivity reaction involves asthma, hayfever, anaphylaxis
Term
Hypersensitivity Type 2
Definition
which type of hypersensitivity reaction involves hemolytic anemia and cytotoxicity
Term
Hypersensitivity type 3
Definition
which type of hypersensitivity reaction involves autoimmune diseases such as systemic lupus erythematosus
Term
Hypersensitivity type 4
Definition
which type of hypersensitivity reaction involves cell mediated immunity, delayed hypersensitivity, and granulomatous diseases such as TB
Term
Penicillin, and type 3
Definition
what is the single most common cause of serum sickness and what type of hypersensitivity reaction is this?
Term
minor aphthous ulcer
Definition
type of aphthous ulcer less than 1cm, usually in anterior of oral cavity, movable mucosa
Term
major aphthous ulcer
Definition
type of aphthous ulcer found on movable mucosa, larger than 1cm, usually found in posterior of oral cavity
Term
herpetiform aphthous ulcer
Definition
which type of aphthous ulcer can be found anywhere in the mouth on movable mucosa and is usually 1-2mm in size. generally in groups
Term
Urticaria
Definition
multiple areas of well demarcated swelling of skin, usually accompanied by pruritus (itching). caused by localized areas of vascular permeability in superficial CT
Term
Angioedema
Definition
diffuse swelling of tissue caused by permeability of deep blood vessels. skin covering appears normal. usually not accompanied by pruitus.
Term
Erythema multiforme
Definition
acute, self limited disease affecting skin and mucous membranes. skin lesions called target, iris, or bulls eye. concentric rings of erythema alternating with normal skin color
Term
arthritis, urethritis, and conjunctivitis
Definition
what is the classic triad of reactive arthritis (Reiter syndrome)?
Term
Langerhan's Cell Disease
Definition
disease, combination of a specific type of macrophage and eosinophils. involved with cell mediated immunity
Term
Sjogren Syndrome
Definition
autoimmune disease which causes extreme xerostomia and affects salivary and lacrimal glands. 90% of patients have positive reaction to rheumatoid factor
Term
systemic lupus erythematosus
Definition
autoimmune disease , causes white erosive lesions on the oral mucosa w/ white striae radiating from center of lesion, and signature butterfly lesion on skin.
Term
pemphigus vulgaris
Definition
autoimmune disease involving breakdown of cellular adhesion and acantholysis. higher the titer of antibodies, greater epithelial destruction. nikolsky's sign in mucusa
Term
mucous membrane / bullous pemphigoid
Definition
oral lesions that heal with scarring due to an autoimmune disease, which can be called one of two things. one: autoantibodies have no correlation with disease, other they do.
Term
Behcet Syndrome
Definition
autoimmune disease consisting of oral ulcers, genital ulcers, ocular inflammation. onset at 30. occurs in individuals from mediterranean region
Term
genotype / phenotype
Definition
the genetic composition vs. the observable appearance, physical, biochemical, and physiologic traits
Term
Alleles
Definition
genes located at the same level (locus) in homologous chromosomes and that dictate the same functions or characteristics
Term
structural
Definition
alterations in ________ proteins are inherited as a dominant trait
Term
enzymatic
Definition
alterations in ________proteins are inherited as a recessive trait
Term
oligogenic inheritance
Definition
characteristics of traits that are inherited by the participation of several genes involves what kind of inheritance
Term
laband syndrome
Definition
autosomal dominant; gingival fibromatosis, dysplastic or absent nails and malformed nose and ears. enlarged liver adn spleen
Term
gingival fibromatosis
Definition
a component of several inherited syndromes. gingival hypertrophy, within a few years teeth are completely covered. involves very firm grandular corrugated surface.
Term
benign fibro-osseous lesion
Definition
benign lesion of bone characterized histologically by cellular fibrous connective tissue admixed with irregularly shaped bone trabeculae or cementoid material
Term
dysplasia
Definition
disordered growth
Term
periapical cemento-osseous dysplasia
Definition
type of benign fibro-osseous lesion which is usually located in the anterior mandible, in black females older than 30. it is associated with vital teeth and involves fibrous connective tissue with numerous calcifications
Term
focal cemento-osseous dysplasia
Definition
a type of benign fibro-osseous lesion which is usually located in the posterior mandible and found in white females age 30-50. its histological findings show several gritty pieces of fibrous connective tissue with bone trabeculae and cementum-like material
Term
Florid cemento-osseous dysplasia
Definition
a type of benign fibro-osseous lesion that can be found anywhere in the oral cavity & usually affects multiple quadrants. its mostly found in black and asian females over 40. composed of masses of irregular opacifications composed of sclerotic bone and cementum & is also prone to osteomylitis
Term
fibrous dysplasia
Definition
a disease characterized by the breakdown and replacement of bone with abnormal fibrous connective tissue interspersed with varying amounts of calcification. thought to be caused by abnormal mesenchymal cell function. characterized by swelling
Term
monostotic fibrous dysplasia
Definition
the most common type of fibrous dysplasia, and involves a single bone, which is usually the maxilla. usually found in children and young adults
Term
polystotic fibrous dysplasia
Definition
type of fibrous dysplasia that involves more than one bone, mostly in female children. also presents cafe au lait lesions with jagged edges. presents a "ground glass appearance"
Term
craniofacial fibrous dysplasia
Definition
a type of polystotic fibrous dysplasia that involves the maxilla with extensions into the maxillary sinuses & adjacent zygoma, sphenoid and occipital bones
Term
jaffe type fibrous dysplasia
Definition
a type of polyostotic fibrous dysplasia that involves multiple bones and cafe au lait lesions. no endocrine abnormalities present
Term
Allbright Syndrome
Definition
a type of polyostotic fibrous dysplasia which involves many bones and is the most severe. also associated with endocrine disturbances, stunted growth, early puberty onset, cafe au lait lesions, and may involve diabetes and/or hyperthyroidism
Term
radiation treatment, because it causes malignant transformation
Definition
what type of treatment is contraindicated for fibrous dysplasia, and why
Term
Paget Disease of bone
Definition
a chronic metabolic bone disease characterized by resorption, osteoblastic repair, and remineralization, enlargement of bone involved and a "cotton wool appearance" on radiographs. typically involves maxilla. the histological findings show "mosaic bone"(prominant reversal lines from resportion and deposition). can form osteosarcomas
Term
bodansky unit
Definition
unit used to measure pagets disease of bone by testing the serum alkaline phosphate levels. the normal range of this unit is 1.5-5, and in disease can be as high as 250
Term
king armstrong unit
Definition
unit used to measure pagets disease of bone by testing the serum alkaline phosphate levels. the normal range of this unit is 5-10, and in disease can be as high as 200
Term
central giant cell granuloma (giant cell reparative granuloma)
Definition
this lesion is composed of well vasularized connective tissue containing many multinucleated giant cells, RBC's, and chronic inflammatory cells. occurs both peripherally (gingival or alveolar mucosa) or centrally (within the bone). has illdefined borders and causes divergence of roots on adjacent teeth to lesion.
Term
brown tumor
Definition
this lesion is identical to a central giant cell granuloma & occurs in patients with hyperparathyroidism. these are not surgically removed and resolve when underlying disease is treated
Term
osteomalacia
Definition
a disease of bone which develops over a long period of time from calcium deficiency or vitamin D deficiency in children. associated with rickets. may be related to chronic use of antacids, or liver and kidney disease. treatment includes nutritional supplements and dietary calcium
Term
bulla
Definition
a circumscribed, elecated lesion that is more than 5 mm in diameter, usually contains serous fluid, and looks liek a blister
Term
lobule
Definition
a segment of lob thats part of the whole; sometimes appear fused together
Term
macule
Definition
different color from surrounding tissue, flat, does not protrude above surface of normal tissue. freckle is an example
Term
papule
Definition
small circumscribed lesion usually less than 1 cm in diameter that is elevated or protrudes above the surface of normal surrounding tissue
Term
pedunculated
Definition
attached by stemlike base similar to mushroom
Term
pustules
Definition
variously sized circumscribed elevations containing pus
Term
sessile
Definition
describing the base of a lesion that is flat or broad instead of stemlike
Term
vesicle
Definition
a small elevated lesion less than 1 cm in diameter that contains serous fluid
Term
nodule
Definition
a palpable solid lesion up to 1 cm in diameter found in soft tissue; it can occue above, level with, or beneath the skin surface
Term
palpation
Definition
evaluation of lesion by feeling it with fingers to determine texture
Term
erythema
Definition
an abnormal redness of the mucosa or gingive
Term
pallor
Definition
paleness of skin or mucosa
Term
corrugated
Definition
wrinkled
Term
fissure
Definition
a cleft or groove showing prominent depth
Term
papillary
Definition
resembling small, nipple shaped projections found in clusters
Term
coalescence
Definition
parts of a whole join together or fuse to make one
Term
diffuse
Definition
describes a lesion with borders that are not well defined
Term
multiocular
Definition
defined as many lobes or parts that are somewhat fused together, resembles soap bubbles
Term
unilocular
Definition
having one compartment or unit that is well defined or outlined
Term
abscess
Definition
a collection of pus that has accumulated in a cavity formed by the tissue
Term
atrophy
Definition
the decrease in size and function of a cell, tissue, organ, or whole body
Term
chemotaxis
Definition
the directed movement of white blood cells to the area of injury by biochemical mediators
Term
c-reactive protein
Definition
a protein produced in the liver that becomes elevated during episodes of acute inflammation or infection
Term
edema
Definition
excess plasma or exudate in the interstitial space of the tissues that causes swelling
Term
emigration
Definition
the passage of white blood cells through the endothelium and wall of the microcirculation into the injured tissue
Term
exudate
Definition
inflammatory fluid formed as a reaction to injury of tissues and blood vessels
Term
hyperemia
Definition
excess of blood in a part of the body
Term
hyperplasia
Definition
an enlargement of a tissue or organ resulting from an increase in the number of normal cells
Term
hypertrophy
Definition
an enlargement of a tissue or organ resulting from an increase in size but not in number of cells
Term
lymphadenopathy
Definition
a condition associated with various disease processes that affect lymph nodes such that they become enlarged
Term
lymphadenopathy
Definition
a condition associated with various disease processes that affect lymph nodes such that they become enlarged
Term
macrophage
Definition
the second white blood cell to arrive at the site of injury; is involved in phagocytosis and also the immune response
Term
margination
Definition
a process during inflammation in which white blood cells tend to move to the periphery of the blood vessel wall
Term
microcirculation
Definition
small blood vessels, including arterioles, capillaries, and venules, all of which can be affected by local changes as the result of inflammation
Term
necrosis
Definition
the pathologic death of one or more cells or a portion of tissue or organ resulting from irreversible damage
Term
neutrophil
Definition
the first white blood cell to arrive at the site of injury; the primary cell involved in acute inflammation; one of the white blood cells with a multilobed nucleus
Term
pavementing
Definition
adherence of white blood cells to the walls of blood vessels during inflammation
Term
phagocytosis
Definition
a process of ingestion and digestion by cells
Term
leukocytosis
Definition
a temporary increase in the number of white blood cells circulating in blood
Term
purulent
Definition
containing or forming pus
Term
regeneration
Definition
the process by which injured tissue is replaced with tissue identical to that present before the injury
Term
serous
Definition
having a watery consistency relating to serum
Term
wheal
Definition
a localized swelling of tissue because of edema during inflammation, often accompanied by severe itching
Term
differential diagnosis
Definition
point in the diagnostic process when you have 2 possible diasnoses andthe biopsy and microscopic examinations provide conclusive info to narrow it down
Term
fordyce granules
Definition
clusters of ectopic sebaceous glands most commonly in buccal mucosa
Term
retrocuspid papilla
Definition
sessile nodule on the gingival margin of the lingual aspect of the mandibular cuspids
Term
leukoedema
Definition
generalized opalescence is imparted to the buccal mucosa. clinically seen as a white film diffused throughout mucosa and is more pronounced in smokers
Term
median rhomboid glossitis
Definition
flat or slightly raised oval or rectangular erythematous area in midline of dorsal surface of tongue. may be associated with chronic fungal infection by candida albicans
Term
redness, heat, swelling, pain, loss of normal tissue function
Definition
the 5 classic signs of inflammation
Term
attrition
Definition
wearing away of tooth structure during mastication, happens normally as a person ages
Term
traumatic neuroma
Definition
injury to a peripheral nerve. proximal end proliferates into a mass of nerve and schwann cells mixed with dense fibrous scar tissue
Term
necrotizing sialometaplasia
Definition
moderately painful swelling and ulceration of the salivary glands
Term
sialolith
Definition
a salivary gland stone formed by the precipitation of calcium salts around a central core
Supporting users have an ad free experience!