Term
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Definition
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Term
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Definition
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Term
| What does SABA stand for? |
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Definition
| Short Acting Beta Agonist |
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Term
| What does LABA stand for? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| What is ipratropium bromide? |
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Definition
| inhaled slow onset drug that prevents airway smooth muscle contraction and mucus secretion. Athma tx. |
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Term
| What asthma drugs are used only in poorly controlled dz and are always used with other drugs? |
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Definition
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Term
| What is DOC for moderate-severe asthma? |
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Definition
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Term
| What are glucocorticoids paired with in asthma tx? |
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Definition
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Term
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Definition
| inhaled glucocorticoid for moderate to severe asthma |
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Term
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Definition
| inhaled glucocorticoid for moderate to severe asthma |
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Term
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Definition
| inhaled glucocorticoid for moderate to severe asthma |
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Term
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Definition
| inhaled glucocorticoid for moderate to severe asthma |
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Term
| What is mometasone furoate? |
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Definition
| dry powder glucocorticoids used q.d. |
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Term
| Why is mometasone furoate easier to administer? |
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Definition
| Does not require hand-breath to be coordinated |
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Term
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Definition
| leukotriene inhibitor to decrease inflammation response in asthma |
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Term
|
Definition
| leukotriene inhibitor to decrease inflammation response in asthma |
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Term
|
Definition
| leukotriene inhibitor to decrease inflammation response in asthma |
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Term
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Definition
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Term
|
Definition
| monoclonal Ab that binds IgE --> decreased mast cell activation |
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Term
| How is omalizumab administered? |
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Definition
| subQ injection q 2-4 weeks |
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Term
|
Definition
| bronchodilator with very low therapeutic index which makes it risky to use |
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Term
| What are SE of theophylline? |
|
Definition
more toxic
seizures
arrythmias |
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Term
| What immunization is useful for chronic bronchitis tx? |
|
Definition
| influenza vaccine reduces morbidity and mortality |
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Term
| What is an enzyme inhibiting potential tx for chronic bronchitis? |
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Definition
| Phosphodiesterase (PDE-4) inhibitors |
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Term
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Definition
| Cystic fibrosis tx that makes sputum less viscous and easier to clear |
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Term
| What are SE of dornase alpha? |
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Definition
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Term
| What is an oral antibiotic for cystic fibrosis tx? |
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Definition
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Term
| What is the mechanism for azithromycin in CF tx? |
|
Definition
| unknown but anti bacterial and anti inflammatory effects suspected |
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Term
| What inhaled AB's are used in CF tx? |
|
Definition
high dose tobramycin and aztreonam
$25k/yr cost |
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Term
| What is a cheap and effective way to treat CF? |
|
Definition
| 7% NaCl inhalation tx. Improves lung fxn and reduces exacerbations |
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Term
| What CF tx risks kidney damage and GI bleeding? |
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Definition
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Term
| What CF drug is specifically useful in younger individuals? |
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Definition
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Term
| What are the major drug classes for treatment of Major Depressive Disorder? |
|
Definition
SSRI
SNRI
TCA
MAO inhibitors
St John's Wort |
|
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Term
| What is a tx option for mild major depressive disorder? |
|
Definition
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Term
| What are drug tx classes for Dysthymic disorder? |
|
Definition
SSRI is primary
TCA and MAOI are secondary |
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Term
| What are drug tx classes for Bipolar disorder? |
|
Definition
mood stabilizers
anti-psychotics
anti-convulsants
anti-depressants |
|
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Term
| What is crucial for proper tx of bipolar disorder? |
|
Definition
never give anti depressants alone
combo a mood stabilizer with an anti-psychotic or SSRI |
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Term
| What drug class do melancholia pt's respond best to? |
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Definition
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Term
| What drug classes are used to treat melancholia? |
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Definition
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Term
|
Definition
full spectrum light therapy
SSRI/SNRI |
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Term
| What drug is not very effective for PMDD? |
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Definition
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Term
| What drugs are used to treat PMDD? |
|
Definition
SSRI (most effective)
Benzodiazepines |
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Term
| What drugs are used to treat GAD? |
|
Definition
SSRI
SNRI
TCA
Benzodiazepines |
|
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Term
| What are best for short term and bridge therapy in GAD? |
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Definition
|
|
Term
| What drugs are used for PTSD and ASD tx? |
|
Definition
SSRI/SNRI/TCA
Benzodiazepines |
|
|
Term
| What drug class is used to treat OCD? |
|
Definition
|
|
Term
| What drug class is used to treat Phobia disorder (PD)? |
|
Definition
| SSRI/SNRI/Benzodiazepines |
|
|
Term
| What drug classes are used to treat symptomatic sarcoidosis? |
|
Definition
| anti-inflammatory medications and immune modulating meds |
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Term
| What anti-inflammatory meds are used in sarcoidosis tx? |
|
Definition
oral corticosteroids: used 12 months with taper
steroid inhalers |
|
|
Term
| What drugs are used to treat severe symptomatic sarcoidosis? |
|
Definition
methotrexate
azathioprine
hydroxychoroquine
cyclosporine |
|
|
Term
| What is DOC for latent TB? |
|
Definition
|
|
Term
| What is the most potent TB drug? |
|
Definition
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|
Term
| How long is Isoniazid taken for? |
|
Definition
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|
Term
| What is the main SE of isoniazid? |
|
Definition
|
|
Term
| What are SE of isoniazid use? |
|
Definition
hepatotoxic
GI
peripheral neuropathy
subepithelial corneal infiltrates
optic neuritis
visual field defects
EOM paresis |
|
|
Term
| What is pyridoxine (Vit B6) used for? |
|
Definition
TB tx
Used in pregant, DM, alcoholics and malnourished pt's |
|
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Term
| What is the advantage of pyridoxine over isoniazid? |
|
Definition
| less risk of peripheral neuropathy |
|
|
Term
| What is the preferred TB tx schedule? |
|
Definition
Isoniazid, Rifampin, Pyrazinamide, Ethambutatol and pyridoxine every day for 8 weeks
THEN Isoniazid and Rifampin with Pyridoxine twice per week for another 18 weeks |
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Term
| Why is TB tx hard on the liver? |
|
Definition
| All of the drugs used are metabolized in the liver |
|
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Term
| What is an IV drug used to treat Histoplasmosis? |
|
Definition
|
|
Term
| What are oral drugs used to treat Histoplasmosis? |
|
Definition
Anti fungals ketoconazole and itraconazole
Lots of SE including N&V, anemia, nephrotoxicity and liver toxicity |
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Term
| If a pt with histplasmosis is immunocompromised, how long must anti-fungals be taken? |
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Definition
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