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Opportunistic Yeasts
Section 8
28
Microbiology
Professional
05/18/2012

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Term
Candida albicans
Definition
world wide
normal HUMAN flora (GI, skin, oropharyngeal, vagina)
person-person, nosocomial, fomites
Term
Candida albicans
Definition
GELATINOUS LESIONS when masses of yeast cause mucoid degeneration, making emboli in brain, spleen, kidneys
Term
Candida albicans
Definition
GRANULOMAS contain yeast cells in leukocyte packed tissue.
Term
Candida albicans
Definition
causes mucocutaneous candidiasis (aka thrush)
presents with glossitis, stomatitis, cheilitis, perleche, vaginitis, balanitis, gastroenteritis, bronchitis
Term
Candida albicans
Definition
Cutaneous ______ causes paronychia, diaper rash, onychomycosis, or candidal granulomas.
Term
Candida albicans
Definition
systemic ________: fever, headache, myalgia, anorexia, arthralgia, uti, heart murmur, hepatosplenomegaly, hematuria, endocarditis, heart valve replacement, and meninigitis produced iatrogenically following prolonged use of antibiotics. associated with narcotic addiction.
Term
Candida albicans
Definition
exudates of infected blood/tissues: chains of OVAL-TO-GLOBOSE BUDDING YEAST CELLS or PSEUDOHYPHAE
Term
Rhodotorulosis (Candida, Rhodotorula, Saccharomyces, and Schizosaccharomyces)
Definition
worldwide AIRBORNE CONTAMINANTS of skin, lungs, urine, and feces as normals HUMAN flora.
person-person,, contaminated needles, catheters, dialysis
Term
Rhodotorulosis (Candida, Rhodotorula, Saccharomyces, and Schizosaccharomyces)
Definition
yeasts seeded into the blood = fungemia with toxic rxns from fermentation by-products
Term
Rhodotorulosis (Candida, Rhodotorula, Saccharomyces, and Schizosaccharomyces)
Definition
FUNGAL PERITONITIS in patients with continuous ambulatory peritoneal dialysis
Term
Rhodotorulosis (Candida, Rhodotorula, Saccharomyces, and Schizosaccharomyces)
Definition
shock with fungemia.
fever, hypotension, tachycardia, endocarditis, meningitis, chills
Fatal infections with lungs, kidneys, heart, CNS
Term
Rhodotorulosis (Candida, Rhodotorula, Saccharomyces, and Schizosaccharomyces)
Definition
PAS shows individual sperical to elongate, budding, non-encapsulated yeast-like cells
Term
Pneumocystis jiroveci
Definition
causes pneumocystosis: fever, chills, non-productive cough, chest pain, congestion, anorexia, sob, weight loss, interstitial plasma cell pneumonia
Term
Pneumocystis jiroveci
Definition
worldwide
normal HUMAN flora and RODENTS
person-person and inhalation of aerosols
Term
Pneumocystis jiroveci
Definition
thick walled, crescent shaped cysts with many internal bodies
Term
Pneumocystis jiroveci
Definition
multily in lung tissue evokes mononuclear cell infiltrate in alveolar septa. reduces oxygen exchange.
consolidation of the lungs
Term
Pneumocystis jiroveci
Definition
Protective immunity (cell-mediated) in immunocompetent
Term
Cryptococcus neoformans and gattii
Definition
worldwide in pigeon dung
inhalation of blastospores from soil and bird droppings
Term
Cryptococcus neoformans and gattii
Definition
CSF/exudate: globose yeast cells with thick, polysaccharide capsules forming halos around cells.
Term
Cryptococcus neoformans and gattii
Definition
partial protective immunity
Term
Cryptococcus neoformans and gattii
Definition
CAPSULAR POLYSACCHARIDES inhibit development of cell-mediated immunity. Activate complement results in depletion of complement.
Term
Cryptococcus neoformans and gattii
Definition
slow resolution, ending with walled-off granuloma remaining in tissue
Term
Cryptococcus neoformans and gattii
Definition
CNS (meningoencephalitis) is most frequently diagnosed form. Gradual onset head ache, fever, n/v, lethargy, nuchal rigidity, photophobia, neck tenderness
Term
cutaneous cryptococcosis
Definition
presents as papules, pustules, ulcers, and abscesses
Term
osseous cryptococcosis
Definition
swelling and pain in bones
Term
Cryptococcus neoformans and gattii
Definition
can cause mucocutaneous lesions, disseminated disease, osseous cryptococcosis, and cutaneous crytpococcosis
Term
Cryptococcus neoformans
Definition
opportunistic and infects immunocompromised
Term
Cryptococcus gattii
Definition
true pathogen associated with flowering eucalyptus tree
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