class: strong agonist

CNS effects: analgesia, euphoria, sedation, antitussive, respiratory depression(death), miosis, emetic, trucal rigidity

Peripheral: constipation

Use: pain, pulmonary edema (DING)

class: strong agonist

enhanced ability to enter CNS

VERY ADDICTIVE

(derp)

class: strong agonist

atropine like effect

NO MIOSIS

do not mix w/ MAOI

class: strong agonist

longer duration w/ lower kinetic activity

used at rehab to get off heroin

class: strong agonist

extremely potent(50x morphine), short duration

use- colonoscopy

does not cause cardio depression

class: strong agonist

used in hospital for pain

not a controlled substance

class: moderate agonist

better bioavailability

use- antitussive

SIZZURP aka PUPRLE DRANK

oxydocone

hydrocodone

class: moderate agonist

use: analgesia

drug seekers choice

class: weak agonist

potency similar to aspirin

can mix w/ etOH to die!!

class: mixed agonist/antagonist

orally effecatious

moderate pain relief, highly sedative

can precipitate withdral in addict

bupenorphine

butorphanol

nalbuphine

class: mixed agonist/antagonist

given by injection

little abuse liability

can precipitate withdrawl in addict

class: antagonist

given IV, reverse opioid overdose

will not cause problem if person turns out ot be not opioid intoxicated

DING- benzo antagonists will cause seizure in a non-benzo intox

class: antagonist

orally effective

can precipitate withdrawal

can use to curb etOH or opioid cravings

liver toxic

class: antagonist

long-acting insectable

loperamide

diphenoxylate

class: antidiarrheal

low abuse potential

class: antitussive

use similar to codeine however no CNS activity

therefore less abuse potential