Opiate Agonists-Antagonists

-          For patients with an addiction

-          Also with liver failure

-          Butorphanol (Stadol)

o   3-5 times more potent than morphine

o   Use to treat moderate to severe pain

o   Use on labor and delivery

o   Do not give with MAOI, risk of hypertensive crisis

-          Naluphine (Nubain)

o   Equal strength

o   No reference to compare

o   VERY POTENT

o   Side effects: NV, cramping, respirator depression, confusion, dizziness, fever, lightheadedness, constipation, decreased GI motility

o   Wean off, don’t adbruptly withdram

o   Lots of fluid for constipation

o    30 times more powerful than morphine

talwin

o   really no comparison to morphine

o   side effects for all- dizziness, decreased GI motility

o    fluid or fiber need to be in the diet to decrease constipation