Term
|
Definition
Naloxone
Naltrexone
Nalmefine
All are said to have no intrinsic action |
|
|
Term
| How do Meperidine differ from others? |
|
Definition
Long term use may accumulate normeperidine: seizures
Atropine-like action, LA action
Moderate to severe pain |
|
|
Term
|
Definition
| Drug seeking behavior 2rd inadequate pain relief |
|
|
Term
| What is cox-2 inhibitor MOA? |
|
Definition
Pain, inflammation, fever, suppression PGI2 without affecting thromboxane A2,
Increased MI, stroke |
|
|
Term
| What is cox-1 inhibitor MOA? |
|
Definition
Inhibit of platelet aggregation
Gastric Ulceration
Renal dysfunction
Hepatocellular injury
Asthma exacerbation
Allergic reactions |
|
|
Term
| What is NSAID characteristics? |
|
Definition
No cognitive effects
No pupillary changes
May decrease GI, breast Ca
May decrease Alzheimer's |
|
|
Term
| What is the effect of Acetaminophen? |
|
Definition
Main action is CNS inhibition of PG synthesis
Analgesic, antipyretic but no antiinflammatory action
Liver toxic but no Reye's |
|
|
Term
|
Definition
|
|
Term
| What is the only IV NSAID in US? |
|
Definition
| Aryl Acetic Acid derivatives |
|
|
Term
| What is Proprionic Acid derivatives? |
|
Definition
|
|
Term
|
Definition
| Tricyclics increase CNS catecholamines |
|
|
Term
|
Definition
| Selective serotonin reuptake inhibitors |
|
|
