| Term 
 
        | what are the adverse effects of First generation H1 blockers |  | Definition 
 
        | Sedative, Anticholinergic(dryMouth), alpha block(lightheaded) |  | 
        |  | 
        
        | Term 
 
        | What are the adverse effects of the 2nd generation anti-histamines |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the first generation anti-histamines And which are associated with anticholinergic, sedative properties, and used in motion sickness |  | Definition 
 
        | Diphenhydramine: chol, sed, motion Dimenhydrinate: chol, sed, motion Tripelenamine: Sedative Hydroxyzine: Sedative Meclizine: Motion Chlorpheniramine Promethazine |  | 
        |  | 
        
        | Term 
 
        | What are the Second Generation Anti-histamines and what are their advantages |  | Definition 
 
        | Loratadine Fexofenadine Cetirizine Terfenadine Less side effects and last 12 hrs |  | 
        |  | 
        
        | Term 
 
        | What is the half life of the first generation Anti-histamines |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What organs have H2 receptors |  | Definition 
 
        | Blood Vessels Heart Myocardium Secretory Tissues |  | 
        |  | 
        
        | Term 
 
        | What organs have H1 receptors, H3 |  | Definition 
 
        | Blood vessels Capillaries Brochioles Uterus Nerve H3 brain |  | 
        |  | 
        
        | Term 
 
        | Drugs that cause histamine release |  | Definition 
 
        | Morphines, Penicillin, NSAID, Polymyxins, Tubocuraine |  | 
        |  |