Term
| Which Vasulitities affect Large vessels, Medium Vessels, and Small vessels |
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Definition
Large: Takayasu's, Giant Cell
Medium: Polyarteritis Nodosa, Kawasaki's
Small: SLE IgA, Good Pasture's, Microscopic Polyangiitis, Wegner's Granulomatosis, Churg-Strauss |
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Term
| Most common systemic vasculitis in adults |
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Definition
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Term
| Leading cause of acquired heart disease in Children? |
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Definition
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Term
| What patient's get Giant cell arteritis and what are the presenting symptoms? |
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Definition
Older Adults
Headache, Painful Pulseless temporal Artery, Optic Disc Hemorrhage |
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Term
| What are the complications and treatment for temporal arteritis and what would a biopsy show |
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Definition
Blindness, Ischemia
Rx: Steroids
Biopsy:Giant cells in Media, Fragmented elastic lamina |
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Term
| Who typically gets takayasu's Arteritis and what are the presenting signs |
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Definition
Young Women
Weak Pulses, Fever, Arthralgia |
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Term
| What arteries are affected by Takayasu's and how is it diagnosed |
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Definition
Aorta and main branches
Dx: Angiography shows narrowing is aortic branches |
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Term
| Who is likely to get Kawasaki's disease and how may it present? |
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Definition
Children <4
Mucocutaneous Lymph Node Syndrome: Fever Conjunctivitis, Oral Erosions, Palm/Plantar Erythema, Lymphadenopathy
Cardiovascular Complications |
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Term
| What vessels are typically affected by kawasaki's disease and how is it diagnosed |
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Definition
Coronary Arteries
Angiography of Coronaries |
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Term
| Who gets polyangitis Nodosa and how does it typically present |
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Definition
Young Adults
Systemic: Weightloss, malais, HPTN
GI Bleeds, Renal Microaneurysms |
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Term
| What vessels does Polyarteritis nodosa affect and how does it progress |
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Definition
Medium vessels (Heart, Renal, Visceral, Not lung)
Transmural Fibrinoid Necrosis-> Non-homogeneous Fibrosis |
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Term
| What people get Microscopic Polyangiitis and what are the signs |
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Definition
Anyone
Palpable Purpura, GN, Weight Loss
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Term
| What vessels are affected by Microscopic Polyangiitis and what does the biopsy show |
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Definition
Pulmonary and Renal arterioles
Diffuse Fibrinoid Necrosis |
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Term
| What people get Wegener's Granulomatosis and what are the sign's |
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Definition
Young/Mid-aged more males
Triad: Necrotizing Vasculitis, URT/LRT Granulomas, Glomerulitis(cresents)
Nasal bridge collapse |
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Term
| What patients get churg-strauss Syndrome and what are the signs and how does it progress |
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Definition
Mid-age with worsening or New asthma
Signs: Sinusitis with Polyps, GN, Mononeuritis Multiplex
Progression: Asthma->Eosinophilia->Vasculitis |
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Term
| Who gets Thromboangiitis Obliterans and how does it present |
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Definition
Young Male Smokers
Raynaud's, Claudication, Gangrene(digital Ulcers)
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Term
| What arteries are typically affected by Thromboangitis obliterans(Beurger's disease) |
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Definition
| Radial and Tibial Arteries |
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