Term
| What is the pathophysiology of Osetoporosis |
|
Definition
Thinning and shrinkage of the bone spicules
Senile: processed caused by hormone imbalance |
|
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Term
| How is osteoporosis treate dand what are the drawbacks |
|
Definition
Estrogen, Calcium, Calcitonin
Estrogen can cause Endometrial Carcinoma |
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|
Term
| What are some identified causes of osteoporosis |
|
Definition
Heparin
Steroids
White
Small Bones
Amenorrhea
Low Exercise
Hereditary
OI
|
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Term
| How do you diagnose Osteoporosis |
|
Definition
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Term
| What is Osteomalacia how does it manifest and how is it diagnosed |
|
Definition
Vit D deficiency
Leg Bowing
Dx: Biopsy or widened seams
Low phosphorous, low calcium
High Alkaline Phosphatase
|
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Term
| Who gets Paget's disease and how does it manifest |
|
Definition
Elderly
Monostotic: tibia
Polystotis: Spine and Pelvis
Eventually can lead to Osteogenic Sarcoma |
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Term
| What is the Pathogenesis of Paget's Disease |
|
Definition
Paramyxovirus Infection of osteoclast leads to oseteolysis and angiogenesis (possible Heart Failure)
Then Oseteolytis and Osteoblastic leads to Mosaic Pattern of of bone growth (Pathognomonic)
Increased osteoblastic activity can cause osteogenic sarcoma |
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Term
| What is a comminuted fracture? |
|
Definition
| Splintered spicules in the bone |
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Term
| what are the most common organisms causing Osteomyelitis |
|
Definition
| S. aureus>Strep pyo>Coliforms |
|
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Term
| What organism is usually associated with osteomyelitis in a patient with Sickle cell |
|
Definition
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Term
| What is a Brodie's Abcess |
|
Definition
| Walling off of an osteomyelitis infection forming an abcess |
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Term
| What is the most common organism causing osteomyitis in an IV Drug User, and a child under 20? |
|
Definition
<20: H.Influenzae
IV: Pseudomonas |
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|
Term
| What is a pseudoarthrosis and what causes it? |
|
Definition
| Improper healing of a fracture forms a new joint space without cartilage or bone |
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